Automated cancer therapy apparatus and method of use thereof

Patent metadata

Field	Value
Publication number	US-10993680-B2
Application number	US-201816131015-A
Country	US
Kind code	B2
Filing date	Sep 13, 2018
Priority date	Apr 16, 2010
Publication date	May 4, 2021
Grant date	May 4, 2021

Abstract

The invention comprises a method and apparatus for treating a tumor, comprising the steps of: (1) a main controller sequentially delivering charged particles from a synchrotron along a first beam transport line, through a nozzle system, and to the tumor according to a current version of the radiation treatment plan; (2) concurrent with the step of delivering, generating an image of the tumor using an imaging system; (3) the main controller automatically generating an updated version of the radiation treatment plan using the image, the updated version of the radiation treatment plan becoming the current version of the radiation treatment plan; and (4) repeating the steps of: delivering grouped bunches of the charged particles, generating an image of the tumor, and automatically generating the updated or current version of the radiation treatment plan with optional intervening doctor approval.

First claim

The invention claimed is:

1. A method for treating a tumor treatment position in a treatment room with positively charged particles, comprising the steps of:
sequentially delivering, via said cancer treatment system, grouped bunches of the positively charged particles from an accelerator along a first beam transport line, through a nozzle system, and to a tumor treatment position;
after treatment of at least one perimeter position of the tumor treatment position generating, with an imaging system, an updated image of the tumor treatment position;
directing the positively charged particles though an extraction foil, reducing speed of the positively charged particles, in an extraction step of the positively charged particles from said accelerator, said accelerator comprising a synchrotron; and
repeating said steps of: (1) delivering grouped bunches of the positively charged particles, (2) generating the updated image of the tumor treatment position, and (3) directing.

2. The method of claim 1 , further comprising the step of:
temporarily slowing but not stopping the process of treating the tumor treatment position by more than fifty percent.

3. The method of claim 1 , further comprising the step of:
after at least one instance of said step of repeating, providing a representation of applied voxel dosage to the tumor treatment position and formulated future voxel dosage relative to the updated image of the tumor treatment position.

4. The method of claim 1 , further comprising the step of:
intermittently verifying an observance of the method of treating the tumor treatment position in a time period of at least three back-to-back iterations of said step of repeating said steps of: (1) delivering grouped bunches of the positively charged particles and (2) generating the updated image of the tumor treatment position.

5. The method of claim 4 , said step of generating the image further comprising the step of:
imaging the tumor treatment position with a second grouped bunch of the positively charged particles and a scintillation detector after treating the tumor treatment position with a first grouped bunch of the positively charged particles and prior to treating the tumor treatment position with a third grouped bunch of the positively charged particles.

6. A method for treating a tumor treatment position in a treatment room with positively charged particles, comprising the steps of:
sequentially delivering, under direction of a cancer therapy system, bunches of the positively charged particles from an accelerator along a first beam transport line, through a nozzle system, and to the tumor treatment position;
after treatment of at least one perimeter position of the tumor treatment position, generating an updated image of the tumor treatment position with an imaging system;
determining, from said updated image of the tumor treatment position, an unpredicted tumor distortion upon treatment;
directing the positively charged particles though an extraction foil, reducing speed of the positively charged particles, in an extraction step of the positively charged particles from said accelerator, said accelerator comprising a synchrotron; and
repeating said steps of: (1) delivering grouped bunches of the positively charged particles, (2) generating an updated image of the tumor treatment position, and (3) directing.

7. The method of claim 6 , further comprising the step of:
during a treatment period, automatically determining a shifted tumor position of a remaining portion of the tumor relative an original position of the tumor.

8. The method of claim 7 , further comprising the step of:
automatically adjusting to the shifted tumor position at least one of: (1) energy of the positively charged particles and (2) direction of the positively charged particles.

9. The method of claim 8 , further comprising the steps of:
calibrating a path of the positively charged particles; and
adjusting the path of the positively charged particles, via an adjustment to compensate for an observed output of at least one fiducial detector linked to at least one fiducial marker linked to a patient positioning system.

10. The method of claim 6 , further comprising the step of:
determining presence of an unplanned for object, with a sensor, in a treatment beam bath of the positively charged particles;
said cancer therapy system automatically adjusting treatment; and
said cancer therapy system automatically continuing treatment of the tumor.

11. The method of claim 10 , further comprising the step of:
determining, with a set of fiducial indicators, relative position of the object, an output zone of the positively charged particles from said nozzle system, and an input zone of the positively charged particles into a patient treatment position, wherein the charged particle beam traverses a linear path from the output zone to the input zone.

Assignees

• Ruebel Nick
• Amato Mark R
• Michaud Susan L
• Bennett James P
• Reno Jillian
• Lee W Davis

Inventors

• Ruebel Nick
• Amato Mark R
• Michaud Susan L
• Bennett James P
• Reno Jillian
• Lee W Davis

Classifications

• A61N5/1069

  Target adjustment, e.g. moving the patient support · CPC title

• G21K5/04

  with beam-forming means · CPC title

• G21K1/08

  Deviation, concentration or focusing of the beam by electric or magnetic means (electron-optical arrangements in electric discharge tubes H01J29/46; {details, e.g. electric or magnetic deviating means for direct voltage accelerators or in accelerators using single pulses H05H5/02; arrangements for injecting particles into orbits H05H7/08; arrangements for ejecting particles from orbits H05H7/10}) · CPC title

• A61N2005/1097

  Means for immobilizing the patient · CPC title

• A61N2005/1095

  Elements inserted into the radiation path within the system, e.g. filters or wedges · CPC title