Modular blood treatment systems, units, and methods

Patent metadata

Field	Value
Publication number	US-10984903-B2
Application number	US-201916568528-A
Country	US
Kind code	B2
Filing date	Sep 12, 2019
Priority date	Dec 21, 2015
Publication date	Apr 20, 2021
Grant date	Apr 20, 2021

Abstract

A portable adapter is provided that can include a closure system configured to control the flow of blood and/or dialysate between the adapter and a blood treatment apparatus. Modular systems are also provided that include the portable adapter engaged with various units such as a portable blood processing module, a non-portable base module, and/or a remote module. Methods of conducting blood treatments such as blood circulation, hemodialysis, and hemofiltration, hemodiafiltration, using the modular systems are also provided. The systems, units, and methods enable the engagement and disengagement of the adapter from the various units to conduct, interrupt, and resume blood treatments without disconnecting the adapter from the vasculature of a patient. Modular systems including interchangeable portable and base modules configured for various blood treatments are also provided that can be engaged and disengaged with each other without disconnecting the portable module from the vasculature of a patient.

First claim

What is claimed is:

1. A modular system comprising:
a first base module comprising a dock and configured to dock a portable extracorporeal blood circuit module, the first base module comprising a base module housing, a primary dialysate circuit comprising a primary dialysate pump, a primary dialysate line, and a first inter-module connector; and
a first portable module configured to dock to the first base module to form a docked configuration, and configured to be undocked from the first base module in an undocked configuration and to operate independently of the first base module in the undocked configuration, the first portable module comprising a first portable module housing, a blood pump mounted in or on the first portable module housing, a first extracorporeal blood circuit tubing set, and a second inter-module connector complementary to the first inter-module connector and configured to connect to the first inter-module connector in the docked configuration, the first portable module configured to circulate blood through the first extracorporeal blood circuit tubing set in the docked configuration and configured to circulate blood through the first extracorporeal blood circuit tubing set in the undocked configuration, independent of the first base module or any other base module, wherein the blood pump is configured to releasably engage the first extracorporeal blood circuit tubing set.

2. The modular system of claim 1 , wherein the primary dialysate circuit further comprises a blood filter in fluid communication with the primary dialysate line, the first inter-module connector is in fluid communication with the blood filter, and the second inter-module connector is in fluid communication with the first extracorporeal blood circuit tubing set.

3. The modular system of claim 2 , wherein the blood filter comprises a dialyzer, and the primary dialysate circuit further comprises a primary heater, a sorbent cartridge, a temperature sensor configured for sensing a temperature of dialysate in the dialysate circuit, a conductivity sensor configured for sensing a conductivity of dialysate in the dialysate circuit, a weighing subsystem configured for weighing dialysate in the dialysate circuit, and a secondary heater.

4. The modular system of claim 1 , wherein the first extracorporeal blood circuit tubing set comprises a blood filter, the blood filter comprises a membrane that separates the blood filter into a blood side of the blood filter and a dialysate side of the blood filter, the dialysate side of the blood filter is in fluid communication with the second inter-module connector, and the primary dialysate line is in fluid communication with the first inter-module connector.

5. The modular system of claim 4 , wherein the first extracorporeal blood circuit tubing set comprises an arterial line, the blood filter, and a venous line, and both the arterial line and the venous line are in fluid communication with the blood side of the blood filter.

6. The modular system of claim 1 , further comprising a central control subsystem comprising a central control user interface and being configured to control the first portable module, wherein the first base module further comprises a primary user interface, and the first portable module further comprises a secondary user interface.

7. The modular system of claim 1 , further comprising a mobile communications device comprising a mobile communications device user interface and being configured to control the first portable module.

8. The modular system of claim 1 , wherein the first base module housing comprises a receptacle at least partially defining the first inter-module connector and being configured to receive and secure at least a portion of the first portable module housing including the second inter-module connector.

9. The modular system of claim 1 , wherein the first portable module comprises a cart, a set of wheels, a wheeled bag, a belt, a waist pack, a neck strap, a shoulder strap, a shoulder harness, a backpack, a chest pack, or any combination thereof.

10. The modular system of claim 1 , wherein the first inter-module connector comprises one or more valves that are configured to be in an open state in the docked configuration and to be in a closed state in the undocked configuration, and wherein the first portable module housing is configured to engage the base module housing at an interface between the first and second inter-module connectors by a hook and loop combination connector, a latch, a lock, a snap-fit connector, a frictional engagement, a magnetic coupling connector, or any combination thereof.

11. The modular system of claim 1 , wherein the first extracorporeal blood circuit tubing set comprises a blood filter, the blood filter comprises a membrane that separates the blood filter into a blood side of the blood filter and a dialysate side of the blood filter, the first portable module further comprises a secondary dialysate circuit comprising a secondary dialysate pump, and the secondary dialysate circuit is in fluid communication with the dialysate side of the blood filter.

12. The modular system of claim 11 , wherein the secondary dialysate circuit further comprises a dialysate reservoir, the second inter-module connector is in fluid communication with the dialysate reservoir, and the secondary dialysate pump is located along the secondary dialysate circuit between the blood filter and the dialysate reservoir.

13. The modular system of claim 1 , wherein the first inter-module connector further comprises a first electrical connector, the second inter-module connector further comprises a second electrical connector that is complementary to the first electrical connector, and the first portable module further comprises a battery-operated auxiliary power source.

14. The modular system of claim 1 , further comprising an engagement verification subsystem configured to generate a detectable signal when the first portable module is securely engaged with the first base module in the docked configuration, wherein the detectable signal comprises a visual signal, an audible signal, a haptic signal, or any combination thereof.

15. The modular system of claim 14 , wherein the engagement verification subsystem is configured to generate a second detectable signal when the first portable module is disengaged from the first base module in the undocked configuration, and the second detectable signal comprises a visual signal, an audible signal, a haptic signal, or any combination thereof.

16. The modular system of claim 1 , further comprising a second portable module configured to dock to the first base module to form a docked configuration, and configured to be undocked from the first base module in an undocked configuration and to operate independently of the first base module in the undocked configuration, the second portable module comprising a second portable module housing, a second blood pump mounted in or on the second portable module housing, a second extracorporeal blood circuit tubing set, and a third inter-module connector complementary to the first inter-module connector and configured to connect to the first inter-module connector, wherein the second blood pump is configured to releasably engage the second extracorporeal blood circuit tubing set.

17. The modular system of claim 16 , wherein the second portable module differs from the first portable module and is configured to perform a different blood treatment on a patient than is the first portable module.

18. The modular system of claim 1 , further comprising a sec

Assignees

• Fresenius Medical Care Holdings Inc

Inventors

• Doyle Matthew
• Tanenbaum Lee
• Halliburton Donovan
• Hoffstetter Eric

Classifications

• A61M2039/1077

  Adapters, e.g. couplings adapting a connector to one or several other connectors · CPC title

• A61M39/1011

  Locking means for securing connection; Additional tamper safeties (A61M39/16 takes precedence) · CPC title

• A61M2205/3337

  Controlling, regulating pressure or flow by means of a valve by-passing a pump · CPC title

• A61M2205/3561

  local, e.g. within room or hospital · CPC title

• G16H20/40 Primary

  relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture · CPC title