Analyte sensor

Patent metadata

Field	Value
Publication number	US-10980452-B2
Application number	US-202017088396-A
Country	US
Kind code	B2
Filing date	Nov 3, 2020
Priority date	Jul 13, 2004
Publication date	Apr 20, 2021
Grant date	Apr 20, 2021

Abstract

The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

First claim

What is claimed is:

1. A system for measuring an analyte concentration in a host, the system comprising:
a transcutaneous analyte sensor;
sensor electronics configured to operatively connect to the transcutaneous analyte sensor;
an electrical contact comprising a first material, wherein the first material is associated with a first durometer hardness, wherein the electrical contact is configured to operably connect the transcutaneous analyte sensor to the sensor electronics;
a sealing member comprising a second material, wherein the second material is associated with a second durometer hardness, wherein the sealing member at least partially surrounds the electrical contact and at least a portion of the transcutaneous analyte sensor when the transcutaneous analyte sensor is operably connected to the sensor electronics, wherein the sealing member substantially seals at least a portion of the electrical contact from moisture;
a contact holder over which the sealing member and the transcutaneous analyte sensor are at least partially located; and
wherein the first durometer hardness is higher than the second durometer hardness.

2. The system of claim 1 , wherein the first durometer hardness is from about 5 Shore A to about 80 Shore A.

3. The system of claim 2 , wherein the second durometer hardness is from about 5 Shore A to about 80 Shore A.

4. The system of claim 2 , wherein the second durometer hardness is from about 20 Shore A to about 50 shore A.

5. The system of claim 1 , wherein the first durometer hardness is from about 5 Shore A to about 80 Shore A and the second durometer hardness is from about 5 Shore A to about 80 Shore A.

6. The system of claim 1 , wherein the first durometer hardness is from about 5 Shore A to about 80 Shore A and the second durometer hardness is from about 10 Shore A to about 50 Shore A.

7. The system of claim 1 , wherein the contact holder is connected to a mounting unit.

8. The system of claim 1 , wherein the contact holder comprises means for maintaining the sealing member on the contact holder.

9. The system of claim 1 , wherein the contact holder and sealing member comprises means for maintaining the sealing member substantially in place on the contact holder.

10. The system of claim 1 , wherein the sealing member is held at least in part on the contact holder by mating male-female mechanical structures on the contact holder and on the sealing member.

11. The system of claim 1 , wherein the sealing member comprises a raised ridge to improve a seal around the electrical contact.

12. The system of claim 1 , wherein the sealing member is held on the contact holder at least in part by protrusions on the contact holder that are configured to mate with recesses on the sealing member.

13. The system of claim 1 , wherein the sealing member is held on the contact holder at least in part by a chemical to maintain the sealing member substantially stationary without substantial translation or deformation during sensor insertion.

14. The system of claim 1 , wherein the sealing member comprises an upper portion and a lower portion, wherein an ex vivo portion of the transcutaneous analyte sensor is sandwiched between the upper portion and the lower portion.

15. The assembly of claim 14 , wherein the upper portion is connected to the lower portion.

16. The system of claim 1 , wherein the sealing member comprises an upper portion and a lower portion, wherein the upper portion comprises an inner face and an outer face, wherein the lower portion comprises an inner face and an outer face, wherein an ex vivo portion of the transcutaneous analyte sensor is positioned between the inner face of the upper portion and the inner face of the lower portion.

17. The assembly of claim 16 , wherein the upper portion is connected to the lower portion.

18. The system of claim 1 , further comprising a memory storing calibration information for the transcutaneous analyte sensor, wherein the calibration information is derived at least in part from a predictive relationship between in vitro sensor sensitivity to the analyte and in vivo sensor sensitivity to the analyte.

19. A system for measuring a glucose concentration in a host, the system comprising:
a transcutaneous glucose sensor;
sensor electronics configured to operably connect to the transcutaneous glucose sensor;
an electrical contact configured to operably connect the transcutaneous glucose sensor to the sensor electronics;
a sealing member comprising a sealing member upper portion and a sealing member lower portion, wherein the sealing member at least partially surrounds the electrical contact and at least a portion of the transcutaneous glucose sensor when the transcutaneous glucose sensor is operably connected to the sensor electronics, wherein the sealing member substantially seals at least a portion of the electrical contact from moisture, and wherein an ex vivo portion of the transcutaneous glucose sensor is sandwiched between the sealing member upper portion and the sealing member lower portion; and
a contact holder over which the sealing member and the transcutaneous glucose sensor are at least partially located.

20. The system of claim 19 , wherein the electrical contact is formed from a material associated with a durometer hardness of from about 5 Shore A to about 80 Shore A.

21. The system of claim 20 , wherein the sealing member is formed from a material associated with a durometer hardness of from about 5 Shore A to about 80 Shore A.

22. The system of claim 20 , wherein the sealing member is formed from a material associated with a durometer hardness of from about 20 Shore A to about 50 shore A.

23. The system of claim 19 , wherein the contact holder is connected to a mounting unit.

24. The system of claim 19 , wherein the contact holder comprises means for maintaining the sealing member on the contact holder.

25. The system of claim 19 , wherein the contact holder and sealing member comprises means for maintaining the sealing member substantially in place on the contact holder.

26. The system of claim 19 , wherein the sealing member is held at least in part on the contact holder by mating male-female mechanical structures on the contact holder and on the sealing member.

27. The system of claim 19 , wherein the sealing member comprises a raised ridge to improve a seal around the electrical contact.

28. The system of claim 19 , wherein the sealing member is held on the contact holder at least in part by protrusions on the contact holder that are configured to mate with recesses on the sealing member.

29. The system of claim 19 , wherein the sealing member is held on the contact holder at least in part by a chemical to maintain the sealing member substantially stationary without substantial translation or deformation during sensor insertion.

30. A system for measuring a glucose concentration in a host, the system comprising:
a transcutaneous glucose sensor;
sensor electronics configured to operably connect to the transcutaneous glucose sensor;
an electrical contact configured to operably connect the transcutaneous glucose sensor to the sensor electronics;
a sealing member comprising a sealing member upper portion and a sealing member lower portion;
wherein the sealing member upper portion comprises an inner face and an outer face, wherein the

Assignees

• Dexcom Inc

Inventors

• Simpson Peter C
• Brauker James H
• Brister Mark C
• Goode Jr Paul V
• Kamath Apurv Ullas
• Masterson Steve
• Mahalingam Aarthi
• Nolting John
• Petisce James R
• Pryor Jack
• Saint Sean
• Swanson Vance
• Wightlin Matthew D

Classifications

• A61B2560/063

  Devices specially adapted for delivering implantable medical measuring apparatus · CPC title

• A61B5/1451

  for interstitial fluid · CPC title

• A61B5/0031

  Implanted circuitry · CPC title

• A61B5/68335

  including release sheets or liners · CPC title

• A61B5/14546

  for measuring analytes not otherwise provided for, e.g. ions, cytochromes · CPC title