N-azaspirocycloalkane substituted N-heteroaryl compounds and compositions for inhibiting the activity of SHP2
US-10336774-B2 · Jul 2, 2019 · US
N-azaspirocycloalkane substituted N-heteroaryl compounds and compositions for inhibiting the activity of SHP2
US10968235B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10968235-B2 |
| Application number | US-201916418978-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 21, 2019 |
| Priority date | Jan 17, 2014 |
| Publication date | Apr 6, 2021 |
| Grant date | Apr 6, 2021 |
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- Title
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- Abstract
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Abstract
Official abstract text for this publication.
The present invention relates to compounds of formula I: in which p, q, Y 1 , Y 2 , R 1 , R 2a , R 2b , R 3a , R 3b , R 4a , R 4b , R 5a , R 5b , R 7 and R 8 are defined in the Summary of the Invention; capable of inhibiting the activity of SHP2. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds and compositions in the management of diseases or disorders associated with the aberrant activity of SHP2.
First claim
Opening claim text (preview).
We claim: 1. A compound, or a pharmaceutically acceptable salt thereof, selected from: 2. A compound which is 3. A compound which is
Assignees
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Classifications
containing further heterocyclic rings · CPC title
Spiro-condensed systems · CPC title
with only one oxygen atom as ring hetero atom in the oxygen-containing ring · CPC title
linked by a carbon chain containing aromatic rings · CPC title
directly linked by a ring-member-to-ring-member bond · CPC title
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- What does patent US10968235B2 cover?
- The present invention relates to compounds of formula I: in which p, q, Y 1 , Y 2 , R 1 , R 2a , R 2b , R 3a , R 3b , R 4a , R 4b , R 5a , R 5b , R 7 and R 8 are defined in the Summary of the Invention; capable of inhibiting the activity of SHP2. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations c…
- Who is the assignee on this patent?
- Novartis Ag
- What technology area does this patent fall under?
- Primary CPC classification C07D401/14. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Apr 06 2021 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 6 related publications on this page (citations in our corpus or others sharing the same primary CPC).