Mitral valve spacer device

Patent metadata

Field	Value
Publication number	US-10959846-B2
Application number	US-201815973892-A
Country	US
Kind code	B2
Filing date	May 8, 2018
Priority date	May 10, 2017
Publication date	Mar 30, 2021
Grant date	Mar 30, 2021

Abstract

An implantable prosthetic device can include a spacer member, a plurality of anchors, and a plurality of clasps. The spacer member can be configured to be disposed between native leaflets of a heart. The anchors can be coupled to the spacer member and configured to secure the native leaflets against the spacer member. The clasps can be coupled to a respective anchor and configured to secure the native leaflets to the anchors. The clasps can be independently movable between an open configuration and a closed configuration.

First claim

The invention claimed is:

1. An implantable prosthetic device, comprising:
a spacer member configured to be disposed between native leaflets of a heart;
a plurality of anchors coupled to the spacer member and configured to secure the native leaflets against the spacer member; and
a plurality of clasps, wherein the clasps are coupled to a respective anchor and are configured to secure the native leaflets to the anchors, and wherein the clasps are independently movable between an open configuration and a closed configuration;
wherein the prosthetic device is movable between a first configuration, in which the spacer member is axially spaced relative to at least a portion of the anchors, and a second configuration, in which the spacer member overlaps the at least a portion of the anchors.

2. The prosthetic device of claim 1 , wherein the first configuration is a compressed configuration, in which the spacer member is radially compressed as well as axially spaced relative to at least a portion of the anchors, and the second configuration is an expanded configuration, in which the spacer member expands radially outwardly relative to the compressed configuration as well as overlapping the at least a portion of the anchors.

3. The prosthetic device of claim 1 , wherein the anchors are pivotable relative to the spacer member between the first configuration and the second configuration, wherein an angle between first portions of the anchors and the spacer member is greater than approximately 120 degrees when the anchors are in the first configuration.

4. The prosthetic device of claim 1 , wherein the anchors have first portions, second portions, and joint portions disposed between the first portions and the second portions, and wherein the first portions are coupled to the spacer member.

5. The prosthetic device of claim 4 , wherein the first portions are spaced relative to the second portions in the compressed configuration and overlap with the second portions in the expanded configuration.

6. The prosthetic device of claim 1 , wherein the at least a portion of the anchors is a second portion of the anchors.

7. The prosthetic device of claim 1 , wherein the clasps comprise attachment portions and arm portions, the attachment portions are coupled to the anchors, and the arm portions are pivotable relative to the attachment portions between the open configuration and the closed configuration.

8. The prosthetic device of claim 7 , wherein the clasps are configured to capture the native leaflets between the attachment portions and the arm portions.

9. The prosthetic device of claim 1 , wherein the clasps are configured to be biased to the closed configuration.

10. The prosthetic device of claim 1 , wherein the clasps are configured to have a preload when the clasps are in the closed configuration.

11. The prosthetic device of claim 1 , wherein the clasps comprise barbs configured to engage tissue of the native leaflets.

12. An implantable prosthetic device, comprising:
a spacer member configured to be disposed between native leaflets of a heart;
a plurality of anchors coupled to the spacer member and configured to secure the native leaflets against the spacer member, wherein the anchors are pivotable relative to the spacer member between a first configuration and a second configuration, and wherein an angle between at least a portion of the anchors and the spacer member is approximately 180 degrees when the anchors are in the first configuration, and the angle between the at least a portion of the anchors and the spacer member is approximately 0 degrees when the anchors are in the second configuration; and
a plurality of clasps, wherein the clasps are coupled to a respective anchor and are configured to secure the native leaflets to the anchors, and wherein the clasps are movable between an open configuration and a closed configuration.

13. The prosthetic device of claim 12 , wherein the anchors have first portions, second portions, and joint portions disposed between the first portions and the second portions, wherein the first portions are coupled to the spacer member, and wherein the at least a portion of the anchors is the first portions of the anchors.

14. The prosthetic device of claim 12 , wherein the clasps are separately movable between the open configuration and the closed configuration.

15. An implantable prosthetic device, comprising:
a spacer member configured to be disposed between native mitral valve leaflets of a heart;
a plurality of anchors coupled to the spacer member, wherein the anchors are configured to secure the native mitral valve leaflets against the spacer member during ventricular systole and to allow the native mitral valve leaflet to move away from the spacer member during ventricular diastole; and
a plurality of clasps, wherein the clasps are coupled to a respective anchor and are configured to secure the native leaflets to the anchors, and wherein the clasps are movable between an open configuration and a closed configuration;
wherein the prosthetic device is movable between a compressed configuration, in which the spacer member is radially compressed and is axially spaced relative to at least a portion of the anchors, and an expanded configuration, in which the spacer member expands radially outwardly relative to the compressed configuration and overlaps the at least a portion of the anchors.

16. The prosthetic device of claim 15 , wherein each of the clasps has a fixed end portion and free end portion, wherein the fixed end portions are coupled to the anchors, wherein the free end portions have barbs, wherein the free end portions are pivotable relative to the fixed end portions between the open configuration and the closed configuration, and wherein the free end portions are axially movable in the open configuration from a first position in which the barbs engage tissue of the native leaflets to a second position in which the barbs disengage the tissue of the native leaflets.

17. An implantable prosthetic device, comprising:
a spacer member configured to be disposed between native leaflets of a heart;
a plurality of anchors coupled to the spacer member and configured to secure the native leaflets against the spacer member; and
a plurality of clasps, wherein the clasps are coupled to a respective anchor and are configured to secure the native leaflets to the anchors, and wherein the clasps are independently movable between an open configuration and a closed configuration;
wherein the anchors are pivotable relative to the spacer member between a first configuration and a second configuration, wherein an angle between first portions of the anchors and the spacer member is approximately 180 degrees when the anchors are in the first configuration, and the angle between the first portions of the anchors and the spacer member is approximately 0 degrees when the anchors are in the second configuration.

18. An implantable prosthetic device, comprising:
a spacer member configured to be disposed between native leaflets of a heart;
a plurality of anchors coupled to the spacer member and configured to secure the native leaflets against the spacer member; and
a plurality of clasps, wherein the clasps are coupled to a respective anchor and are configured to secure the native leaflets to the anchors, and wherein the clasps are independently movable between an open configuration and a closed configuration;
wherein the spacer member and the anchors are formed from a single, unitary piece of material.

19. An implantable pr

Assignees

• Edwards Lifesciences Corp

Inventors

• Marr Devin H
• Delgado Sergio
• Dixon Eric Robert
• Taylor David M
• Metchik Asher L
• Winston Matthew T
• Stearns Grant Matthew
• Sok Sam
• Nguyen Tam Van
• Kwon Rhayoung
• Wu Victoria Cheng-Tan
• White Amanda Kristine Anderson

Classifications

• A61F2/9517

  handle assemblies therefor · CPC title

• A61F2/2466

  Delivery devices therefor · CPC title

• A61F2220/0075

  sutured, ligatured or stitched, retained or tied with a rope, string, thread, wire or cable · CPC title

• A61F2220/0016

  with sharp anchoring protrusions, e.g. barbs, pins, spikes · CPC title

• A61F2220/0008

  Fixation appliances for connecting prostheses to the body · CPC title