Manifold for automatic drug compounder

Patent metadata

Field	Value
Publication number	US-10954007-B2
Application number	US-201615780609-A
Country	US
Kind code	B2
Filing date	Nov 29, 2016
Priority date	Dec 4, 2015
Publication date	Mar 23, 2021
Grant date	Mar 23, 2021

Abstract

A manifold for control of fluid and/or vapor flow between a container and a pump cartridge for a compounder system is provided. One or more manifolds may be disposed in a magazine configured to secure and align the manifolds with a plurality of ports in the cartridge. Each manifold may include a needle having forward and rear openings to a central bore. A needle housing may include a slot configured to receive a push rod for actuating the needle forward and backward. In a forward, engaged position, the openings in the needle may be disposed on opposite sides of a sealing member of the manifold to form a fluid pathway through the manifold. In a rearward, disengaged position, both the forward and rear openings in the needle may be disposed on the same side of the sealing member to prevent fluid and vapor from flowing through the manifold.

First claim

What is claimed is:

1. A manifold, comprising:
a housing;
a cap assembly comprising:
a cap defining an opening, the opening having an opening diameter; and
a first sealing member comprising an extended portion having an extended portion diameter, wherein the opening diameter is smaller than the extended portion diameter, and the extended portion of the first sealing member is compressed by an edge of the opening to radially compress the first sealing member;

a needle guide assembly having a second sealing member; and
a needle assembly having a needle with a central bore, a first opening, and a second opening,
wherein the needle assembly is extendible from a disengaged position in which the first and second openings are both disposed on a common side of the first sealing member between the first and second sealing members and an engaged position in which the first and second openings are disposed on opposing sides of the first sealing member, and the needle assembly is wiped by the compressed first sealing member as the needle assembly is retracted from the first sealing member.

2. The manifold of claim 1 , wherein the housing comprises an opening configured to receive tubing from a container, and wherein, in the engaged position, the needle assembly is configured to allow flow of a liquid or a vapor through the opening in the housing, through the first and second openings in the needle, and through the central bore of the needle.

3. The manifold of claim 2 , wherein the needle guide assembly comprises an inner housing having a central bore, and wherein the needle assembly comprises a needle housing configured to slide within the central bore of the inner housing.

4. The manifold of claim 3 , wherein the needle housing comprises a slot configured to receive a needle push rod for actuating the needle assembly between the disengaged and engaged positions.

5. The manifold of claim 4 , wherein the inner housing of the needle guide assembly comprises a cutout configured to provide access to the slot of the needle housing when the needle housing is in the disengaged position.

6. The manifold of claim 5 , wherein the inner housing of the needle guide assembly comprises at least one snap feature configured to engage with the housing of the manifold to secure the needle guide assembly within the housing.

7. The manifold of claim 2 , wherein the first sealing member is disposed within the cap and wherein the cap is configured to snap onto the housing.

8. The manifold of claim 7 , wherein the edge of the opening bears against the extended portion of the first sealing member to radially compress the first sealing member by approximately 10 percent of the diameter.

9. A compounder system, comprising:
a pump head assembly having a recess and a plurality of operational mechanisms;
a magazine configured to be received in the recess;
a manifold configured to be received in the magazine, the manifold comprising:
a cap assembly comprising:
a cap defining an opening, the opening having an opening diameter; and
a first sealing member comprising an extended portion having an extended portion diameter, wherein the opening diameter is smaller than the extended portion diameter, and the extended portion of the first sealing member is compressed by an edge of the opening to radially compress the first sealing member;

a container fluidly coupled to the manifold; and
a pump cartridge configured to be operated by the plurality of operational mechanisms of the pump drive to pump a fluid from the container through the manifold into the pump cartridge,
wherein the manifold comprises a needle assembly having a disengaged configuration in which the needle assembly is completely disposed within the manifold such that the manifold prevents flow of the fluid and an engaged configuration in which the needle of the needle assembly extends from the manifold into the pump cartridge such that the needle forms a portion of a sealed fluid pathway from the container to the pump cartridge.

10. The compounder system of claim 9 , wherein the pump cartridge comprises:
a frame having an opening; and
a compliant membrane disposed adjacent the frame,
wherein, in the engaged configuration, the needle extends through the opening in the frame and through the compliant membrane into the pump cartridge.

11. The compounder system of claim 10 , wherein the sealing member is configured to be pressed against the compliant membrane of the pump cartridge, and wherein, in the engaged configuration, the needle extends through the sealing member of the cap assembly of the manifold and through the opening in the frame and through the compliant membrane into the pump cartridge.

12. The compounder system of claim 9 , wherein the magazine comprises a plurality of recesses configured to receive a plurality of manifolds.

13. The compounder system of claim 12 , wherein each recess comprises alignment features configured to guide a corresponding manifold into the recess and prevent incorrect installation of any manifold in the recess.

14. The compounder system of claim 13 , wherein the plurality of recess comprises a plurality of diluent manifold recesses and at least one waste manifold recess, wherein the alignment features in the diluent manifold recesses are different from the alignment features in the waste manifold recess.

15. The compounder system of claim 13 , wherein the magazine further comprises a pair of squeezable grips configured to facilitate installation and removal of the magazine from the recess of the pump head assembly.

Assignees

• Carefusion 303 Inc

Inventors

• Feith Ray
• Wang Vincent Fuji
• Quitoviera Neil
• Mansour George Michel
• Zollinger Christopher J
• Quach Matthew

Classifications

• B65B3/003 Primary

  Filling medical containers such as ampoules, vials, syringes or the like · CPC title

• A61J3/002 Primary

  Compounding apparatus specially for enteral or parenteral nutritive solutions (bottling liquids B67C) · CPC title

• B65B3/12

  mechanically, e.g. by pistons or pumps · CPC title

• A61M39/10

  Tube connectors; Tube couplings {(A61M39/02 takes precedence; connecting needles to syringes or hubs A61M5/34; connecting catheter tubes to hubs A61M25/0014)} · CPC title

• A61J1/2075

  for external venting · CPC title