Precise accurate measurement of the administration of drugs using the injection method by means of ultrasonic pulse-echo principles
US-9907902-B2 · Mar 6, 2018 · US
US10953155B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10953155-B2 |
| Application number | US-201715471358-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 28, 2017 |
| Priority date | Apr 29, 2016 |
| Publication date | Mar 23, 2021 |
| Grant date | Mar 23, 2021 |
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A plunger head for a fluid injection device includes a transducer disposed in the plunger head to measure a compressive force when applied to the plunger head. The plunger head also includes a power source and a microcontroller disposed in the plunger head. The microcontroller is coupled to the power source and the transducer, and the microcontroller is coupled to enter a high-power mode in response to sensing application of the compressive force to the plunger head.
Opening claim text (preview).
What is claimed is: 1. A plunger head for a fluid injection device, comprising: a transducer disposed in the plunger head to output a signal when a compressive force is applied to the plunger head, wherein the signal is indicative of the compressive force; a power source disposed in the plunger head; a temperature sensor disposed in the plunger head to measure a temperature of a fluid in the fluid injection device; and a microcontroller, disposed in the plunger head, coupled to the power source, the transducer, the temperature sensor, and a memory, the memory including instructions that when executed by the microcontroller causes the plunger head to perform operations including: transition between individual modes included in a plurality of operative modes of the plunger head in response to the microcontroller receiving the signal output by the transducer, wherein the plurality of operative modes includes a power conservation mode, a high-power mode, a low frequency temperature measurement state, and a high frequency temperature measurement state, wherein the plunger head consumes more power when in the high-power mode relative to when the plunger head is in the power conservation mode; and periodically measure the temperature of the fluid with the temperature sensor when the plunger head is in either the low frequency temperature measurement state or the high frequency temperature measurement state, wherein a measurement frequency of the low frequency temperature measurement state is less than that of the high frequency temperature measurement state. 2. The plunger head of claim 1 , wherein there is no electrical contact between the power source and the microcontroller when the plunger head is in the power conservation mode. 3. The plunger head of claim 2 , wherein the transducer includes a force sensor, and wherein the signal output by the transducer is indicative of a force profile included in the compressive force, and wherein in response to the compressive force the force sensor couples the microcontroller and the power source to initiate transition of the plunger head to the high-power mode based on the force profile. 4. The plunger head of claim 3 , wherein the power conservation mode is an off-state. 5. The plunger head of claim 1 , wherein the transition of the plunger head between the individual modes included in the plurality of operative modes of the plunger head is based on a force profile included in the compressive force and measured by the transducer, and wherein the force profile corresponds to at least one of application of forces in succession to the plunger head or an extended application of force to the plunger head. 6. The plunger head of claim 1 , wherein the memory includes additional instructions that when executed by the microcontroller causes the plunger head to perform further operations including: identify one of different force profiles as being included in the compressive force applied to the plunger head based on the signal output by the transducer; and transition to one of the plurality of operative modes of the plunger head based on the identified one of the different force profiles. 7. The plunger head of claim 6 , wherein the plurality of operative modes further include at least one of an off-state, a fluid quantity measurement state, or a data transfer state. 8. The plunger head of claim 1 , wherein the transducer or a second transducer is coupled to the microcontroller to send and receive ultrasonic signals, and wherein the memory includes additional instructions that when executed by the microcontroller causes the plunger head to perform further operations including: send and receive the ultrasonic signals with at least one of the transducer or the second transducer when the plunger head is in the high-power mode. 9. The plunger head of claim 8 , wherein the memory includes additional instructions that when executed by the microcontroller causes the plunger head to perform further operations including: calculate a quantity of the fluid in the fluid injection device when the plunger head is inserted in the fluid injection device, in response to the sending and receiving of the ultrasonic signals, and wherein sending and receiving the ultrasonic signals includes sending the ultrasonic signals along a length of the fluid injection device, reflecting the ultrasonic signals back towards the plunger head, and receiving the ultrasonic signals with the transducer or the second transducer. 10. A drug delivery system to inject a fluid, comprising: a vessel including an interior cavity to hold the fluid; a plunger disposed in the drug delivery system to exert a compressive force on a plunger head; and the plunger head disposed in the interior cavity to expel the fluid from the vessel in response to the compressive force from the plunger, the plunger head including: a transducer disposed in the plunger head to output a signal when the compressive force is exerted on the plunger head, wherein the signal is indicative of the compressive force; a power source disposed in the plunger head; a temperature sensor disposed in the plunger head to measure a temperature of the fluid in the vessel; and a microcontroller, disposed in the plunger head, coupled to the power source the transducer, the temperature sensor, and a memory, the memory including instructions that when executed by the microcontroller causes the drug delivery system to perform operations including: transition the plunger head between individual modes included in a plurality of operative modes of the plunger head in response to the microcontroller receiving the signal output by the transducer, wherein the plurality of operative modes includes a power conservation mode, a high-power mode, a low frequency temperature measurement state, and a high frequency temperature measurement state, wherein the plunger head consumes more power when in the high-power mode relative to when the plunger head is in the power conservation mode; and periodically measure the temperature of the fluid with the temperature sensor when the plunger head is in either the low frequency temperature measurement state or the high frequency temperature measurement state, wherein a measurement frequency of the low frequency temperature measurement state is less than that of the high frequency temperature measurement state. 11. The drug delivery system of claim 10 , wherein there is no electrical contact between the power source and the microcontroller when the plunger head is in the power conservation mode. 12. The drug delivery system of claim 10 , wherein the transducer includes a force sensor, and wherein the signal output by the transducer is indicative of a force profile included in the compressive force, and wherein the memory includes additional instructions that when executed by the microcontroller causes the drug delivery system to perform further operations including: transition the plunger head between the plurality of operative modes in response to the compressive force including the force profile, wherein the force profile corresponds to at least one of application of forces in succession to the plunger head or an extended application of force to the plunger head. 13. The drug delivery system of claim 10 , wherein the memory includes additional instructions that when executed by the microcontroller causes the drug delivery system to perform further operations including: identify one of different force profiles as being included n the compressive force exerted on the plunger head based on the signal output by the transducer; and transition to one of the plurality of operati
Piston or piston-rod constructions, e.g. connection of piston with piston-rod (A61M5/5066 takes precedence) · CPC title
Temperature · CPC title
Means keeping track of the total dose administered, e.g. since the cartridge was inserted · CPC title
by audible feedback · CPC title
Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically (A61M5/142 {, A61M5/46} take precedence; {hypodermic projectiles F42B12/54}) · CPC title
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