Oral care compositions and dispensing system therefor

Patent metadata

Field	Value
Publication number	US-10952937-B2
Application number	US-201715664692-A
Country	US
Kind code	B2
Filing date	Jul 31, 2017
Priority date	Sep 28, 2016
Publication date	Mar 23, 2021
Grant date	Mar 23, 2021

Abstract

The present disclosure provides a capsule comprising one or more solid oral care ingredients, said capsule being adapted for use in an apparatus that combines a solvent, for example water, and the oral care ingredients to provide a liquid, for example aqueous, oral care composition. The present disclosure also provides apparatus adapted to provide an aqueous oral care composition by directing water through the capsule; aqueous oral care compositions prepared by use of the capsule and/or apparatus, and methods for the use of the aqueous oral care compositions.

First claim

What is claimed is:

1. A capsule comprising a mixture of solid oral care ingredients within a hollow container, said capsule being adapted for use in an apparatus that combines a solvent, wherein said solvent is water, and said mixture of solid oral care ingredients to provide a mouthwash composition;
wherein the mixture of solid oral care ingredients comprise
a) complexed or uncomplexed hydrogen peroxide;
b) arginine bicarbonate; and
c) an active selected from the group consisting of tetrasodium pyrophosphate, sodium fluoride, tetrapotassium pyrophosphate, potassium nitrate, cetylpyridinium chloride, and an acid source which is selected from the group consisting of citric acid, malic acid, tartaric acid, adipic acid, alginic acid, succinic acid, lactic acid, potassium bitartrate, acid sodium citrate, phosphoric acid, pyrophosphate salts, fumaric acid and mixtures thereof;

wherein the mixture of solid oral care ingredients are incompatible when stored together in solution.

2. The capsule of claim 1 , wherein said mixture of solid oral care ingredients are present in an amount sufficient to provide a single unit dose of said oral care composition.

3. The capsule of claim 1 , wherein said mixture of solid oral care ingredients are present in an amount sufficient to provide multiple doses of said oral care composition.

4. The capsule of claim 1 , wherein said mixture of solid oral care ingredients further comprises one or more additional ingredients selected from the group consisting of analgesic agents, antipyretic agents, anti-inflammatory agents, opioids, and vitamins.

5. The capsule of any preceding claim 1 , wherein said mixture of solid oral care ingredients further comprises one or more additional ingredients selected from the group consisting of ibuprofen, acetaminophen, and medications which are psychotropic, anti-hypersensitive, anti-seizure, amphetamine, antimicrobial, antibiotic, anti-viral, anti-retroviral, anti-fungal, anti-depressant, stimulants, anti-histamine, anti-anxiety, tricyclics, tranquilizers, benzodiazepines, hypnotics, mood stabilizers, codeine, selective serotonin reuptake inhibitors, antiallergy, phenothiazine, chemotherapeutics, amines, monoamine oxidase inhibitors, anti-carcinogens, analgesics, muscle relaxants, ergot preparations, anticholinergic, anti-inflammatory, anti-gout preparations, soporific, hormonal preparations, appetite suppressants, analgesics, muscle relaxants, opioids, and combinations thereof.

6. The capsule of claim 1 , wherein said oral care ingredients are in the form of a powder or granulate.

7. The capsule of claim 1 , wherein said solvent is a mixture comprising water and a humectant, wherein said humectant is glycerin or propylene glycol.

8. The capsule of claim 1 , wherein at least one of the solid oral care ingredients in the capsule is sequestered from the other solid ingredients within the capsule.

9. The capsule of claim 1 , wherein said container:
a) is in the shape of a truncated cone; and
b) is adapted for the introduction of solvent and the egress of solvent together with the oral care ingredients.

10. A method for preparing an oral care composition, comprising directing a solvent through the capsule according claim 1 ; whereupon the solvent dissolves at least one of said oral care ingredients in said capsule to form said oral care composition.

11. A method for one or more of:
a) cleansing the teeth and oral cavity;
b) freshening breath;
c) reducing formation of dental caries;
d) reducing erosion;
e) reducing or repairing pre-carious lesions of the enamel, e.g., as detected by quantitative light-induced fluorescence (QLF) or electrical conductance measurement (ECM);
f) reducing demineralization and promote remineralization of the teeth;
g) reducing gingivitis
h) improving oral health;
i) whitening teeth;
j) promoting healing of sores or cuts in the mouth;
k) reducing levels of acid producing bacteria;
l) increasing relative levels of arginolytic bacteria;
m) reducing plaque accumulation;
n) reducing microbial biofilm formation in the oral cavity;
o) immunizing the teeth against cariogenic bacteria;
p) reducing the amount of bacteria in an oral cavity;
q) reducing dentinal sensitivity;
r) enhancing systemic health, and/or
s) treating dry mouth;

comprising contacting an oral cavity of a patient in need thereof with the oral composition prepared by the method of a claim 10 .

12. An oral care composition prepared by the method of claim 10 .

Assignees

• Colgate Palmolive Co

Inventors

• Pierce Robert
• Jayaraman Nagarajan

Classifications

• A61K8/022

  Powders; Compacted Powders · CPC title

• A61K8/19

  containing inorganic ingredients · CPC title

• A61K8/11 Primary

  Encapsulated compositions · CPC title

• A61K8/375

  the alcohol moiety containing more than one hydroxy group · CPC title

• A61K8/21

  Fluorides; Derivatives thereof · CPC title