Heteroaryl SYK inhibitors

US10947243B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-10947243-B2
Application numberUS-201916535337-A
CountryUS
Kind codeB2
Filing dateAug 8, 2019
Priority dateMar 19, 2014
Publication dateMar 16, 2021
Grant dateMar 16, 2021

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

The invention relates to new substituted heteroaryls of formula 1 wherein A is selected from the group consisting of N and CH D is selected from the group consisting of CH, N, NH, S and O, E is selected from the group consisting of C and N, T is selected from the group consisting of C and N, G is selected from the group consisting of C and N, and wherein each of the broken (dotted) double bonds in ring 1 are selected from either a single bond or a double bond under the proviso that all single and double bonds of ring 1 are arranged in such a way that they all form together with ring 2 an aromatic ring system, and wherein R 1 , M and R 3 are defined according to claim 1 , and to the above compounds for the treatment of a disease selected from the group consisting of asthma, COPD, allergic rhinitis, allergic dermatitis, lupus erythematodes, lupus nephritis and rheumatoid arthritis.

First claim

Opening claim text (preview).

The invention claimed is: 1. A method of treating pulmonary arterial hypertension comprising the step of administering to a person in need thereof a compound of the following formula: or a pharmaceutically acceptable salt thereof. 2. A method of treating comprising the step of administering to a person in need thereof a compound of the following formula: or a pharmaceutically acceptable salt thereof.

Assignees

Inventors

Classifications

  • containing three or more hetero rings · CPC title

  • condensed with carbocyclic rings, e.g. benzimidazoles · CPC title

  • of the kidneys · CPC title

  • linked by a chain containing hetero atoms as chain links · CPC title

  • for bone diseases, e.g. rachitism, Paget's disease · CPC title

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Frequently asked questions

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What does patent US10947243B2 cover?
The invention relates to new substituted heteroaryls of formula 1 wherein A is selected from the group consisting of N and CH D is selected from the group consisting of CH, N, NH, S and O, E is selected from the group consisting of C and N, T is selected from the group consisting of C and N, G is selected from the group consisting of C and N, and wherei…
Who is the assignee on this patent?
Boehringer Ingelheim Int
What technology area does this patent fall under?
Primary CPC classification A61K31/416. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Mar 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 7 related publications on this page (citations in our corpus or others sharing the same primary CPC).