Systems and methods for oxygenator performance evaluation

Patent metadata

Field	Value
Publication number	US-10940257-B2
Application number	US-201715805896-A
Country	US
Kind code	B2
Filing date	Nov 7, 2017
Priority date	Nov 8, 2016
Publication date	Mar 9, 2021
Grant date	Mar 9, 2021

Abstract

Systems and methods for monitoring oxygenator performance in extracorporeal circuit systems or the like. More particularly, the disclosure relates to systems and methods including a controller programmed to determine oxygenator apparatus flow impedance as a function of an inlet pressure measurement, an outlet pressure measurement and a blood flow rate measurement. The systems and methods may include a communication device that receives signals from the controller to communicate information regarding oxygenator apparatus performance.

First claim

What is claimed is:

1. A system for oxygenating blood in an extracorporeal circuit, the system comprising:
an oxygenator apparatus including:
a housing defining a blood inlet port, a blood outlet port and a blood flow path from the blood inlet port to the blood outlet port, and
a fiber bundle disposed within the housing and including a plurality of gas exchange elements;

a first sensor proximate the blood inlet port for generating an inlet pressure measurement;
a second sensor proximate the blood outlet port for generating an outlet pressure measurement;
a third sensor for generating a blood flow rate measurement;
a communication device; and
a controller electronically connected to the first, second and third sensors and the communication device, the controller programmed to:
determine oxygenator apparatus flow impedance as a function of the inlet pressure measurement, the outlet pressure measurement and the blood flow rate measurement,
determine a baseline oxygenator apparatus flow impedance at a first point in time,
determine a current oxygenator apparatus flow impedance at a second point in time, the second point in time being after the first point in time, and
prompt the communication device to communicate information indicative of the determined oxygenator apparatus flow impedance including a comparison between the baseline oxygenator apparatus flow impedance and the current oxygenator flow apparatus impedance.

2. The system of claim 1 , wherein the controller is programmed to determine oxygenator apparatus flow impedance as:
(inlet pressure measurement−outlet pressure measurement)/blood flow rate measurement.

3. The system of claim 1 , wherein the communication device and the controller are carried by the housing.

4. The system of claim 1 , wherein the communication device and the controller are separate from the housing.

5. The system of claim 1 , wherein at least one of the first, second and third sensors are carried by the housing.

6. The system of claim 1 , wherein at least one of the first, second and third sensors are not attached to the housing.

7. The system of claim 1 , wherein the communication device provides a communication selected from the group consisting of a visual communication and an audible communication.

8. The system of claim 1 , wherein the third sensor is proximate the blood outlet port.

9. A system for oxygenating blood in an extracorporeal circuit, the system comprising:
an oxygenator apparatus including:
a housing defining a blood inlet port, a blood outlet port and a blood flow path from the blood inlet port to the blood outlet port, and
a fiber bundle disposed within the housing and including a plurality of gas exchange elements;

a first sensor proximate the blood inlet port for generating an inlet pressure measurement;
a second sensor proximate the blood outlet port for generating an outlet pressure measurement;
a third sensor for generating a blood flow rate measurement;
a communication device; and
a controller electronically connected to the first, second and third sensors and the communication device, the controller programmed to:
determine oxygenator apparatus flow impedance as a function of the inlet pressure measurement, the outlet pressure measurement and the blood flow rate measurement,

determine a first oxygenator apparatus flow impedance at a first point in time,
determine a second oxygenator flow apparatus impedance at a second point in time, the second point in time being after the first point in time,
determine a difference between the first and second oxygenator apparatus flow impedances, and
prompt the communication device to communicate information indicative of the determined oxygenator apparatus flow impedance including prompt the communication device to communicate an alert when the determined difference exceeds a predetermined value.

10. A system for oxygenating blood in an extracorporeal circuit, the system comprising:
an oxygenator apparatus including:
a housing defining a blood inlet port, a blood outlet port and a blood flow path from the blood inlet port to the blood outlet port, and
a fiber bundle disposed within the housing and including a plurality of gas exchange elements;

a first sensor proximate the blood inlet port for generating an inlet pressure measurement;
a second sensor proximate the blood outlet port for generating an outlet pressure measurement;
a third sensor for generating a blood flow rate measurement;
a communication device; and
a controller electronically connected to the first, second and third sensors and the communication device, the controller programmed to:
determine oxygenator apparatus flow impedance as a function of the inlet pressure measurement, the outlet pressure measurement and the blood flow rate measurement,
prompt the communication device to communicate information indicative of the determined oxygenator apparatus flow impedance,
generate oxygenator apparatus flow impedance trending information based on a multiplicity of sequentially determined oxygenator apparatus flow impedances, and
determine an end-of-life criteria for the oxygenator apparatus based upon the oxygenator apparatus flow impedance trending information.

11. An oxygenator apparatus for oxygenating blood in an extracorporeal circuit, the oxygenator apparatus comprising:
a housing defining a blood inlet port, a blood outlet port and a flow path from the blood inlet port to the blood outlet port;
a fiber bundle disposed within the housing and including a plurality of gas exchange elements;
a first sensor carried by the housing for sensing an inlet pressure measurement proximate the blood inlet port;
a second sensor carried by the housing for sensing a outlet pressure measurement proximate the blood outlet port;
a third sensor for generating a blood flow rate measurement;
a communication device; and
a controller electronically connected to the first, second and third sensors and the communication device, the controller programmed to:
determine oxygenator apparatus flow impedance as a function of the inlet pressure measurement, the outlet pressure measurement and the blood flow rate measurement,
determine a baseline oxygenator apparatus flow impedance at a first point in time,
determine a current oxygenator apparatus flow impedance at a second point in time, the second point in time being after the first point in time, and
prompt the communication device to communicate information indicative of the determined oxygenator apparatus flow impedance including prompt the communication device to communicate information indicative of a comparison between the baseline oxygenator apparatus flow impedance and the current oxygenator apparatus flow impedance.

12. The apparatus of claim 11 , wherein the communication device provides a communication selected from the group consisting of a visual communication and an audible communication.

13. The apparatus of claim 11 , wherein the third sensor is proximate the blood outlet port.

14. The apparatus of claim 11 , wherein the controller is programmed to determine oxygenator apparatus flow impedance as:
(inlet pressure measurement−outlet pressure measurement)/blood flow rate measurement.

15. An oxygenator apparatus for oxygenating blood in an extracorporeal circuit, the oxygenator apparatus comprising:
a housing defining a blood inlet port, a blood outlet port and a flow path from the blood inlet port to the blood outlet port;
a fiber bundle disposed within the housing and including a plurality of gas exchange elements;
a first sensor carried

Assignees

• Medtronic Vascular Inc

Inventors

• Steffens Brian
• Beavers James
• Knoll John
• Romine Todd

Classifications

• A61M2205/707

  Testing of filters for clogging · CPC title

• A61M2205/70

  with testing or calibration facilities · CPC title

• A61M2205/584

  having a color code · CPC title

• A61M2205/581

  by audible feedback · CPC title

• A61M1/1698 Primary

  Blood oxygenators with or without heat-exchangers (intracorporal A61M1/1678; manufacturing of membranes therefor B01D67/00; semi-permeable membranes for separation processes characterised by their properties B01D69/00; semi-permeable membranes characterised by their material B01D71/00) · CPC title