Methods and systems for integrated radiopharmaceutical generation, preparation, transportation and administration
US-10016618-B2 · Jul 10, 2018 · US
US10933186B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10933186-B2 |
| Application number | US-201716346219-A |
| Country | US |
| Kind code | B2 |
| Filing date | Nov 21, 2017 |
| Priority date | Nov 22, 2016 |
| Publication date | Mar 2, 2021 |
| Grant date | Mar 2, 2021 |
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Provided is a method for delivering a medical fluid. The method includes delivering a fluid volume, which includes contrast and/or a flush fluid, at a preselected total volumetric flowrate during a first duration of a fluid delivery procedure. The amount of the contrast agent and the flush fluid in the fluid volume can be controllably varied during the first duration of the fluid delivery procedure so as to substantially maintain a preselected total volumetric flowrate throughout the first duration of the fluid delivery procedure. Also provided is a fluid delivery system capable of performing this method.
Opening claim text (preview).
The invention claimed is: 1. A method for delivering a medical fluid, comprising: delivering a fluid volume at a preselected total volumetric flowrate during a first duration of a fluid delivery procedure, wherein the fluid volume is comprised of a volumetric amount of a contrast agent and a volumetric amount of a flush fluid; controllably varying the volumetric amount of the contrast agent in the fluid volume during the first duration of the fluid delivery procedure, wherein the volumetric amount of the contrast agent is controllably increased during at least a portion of the first duration; and controllably decreasing the volumetric amount of the flush fluid in the fluid volume while the volumetric amount of the contrast agent is being controllably increased so as to substantially maintain the preselected total volumetric flowrate throughout the first duration of the fluid delivery procedure. 2. The method of claim 1 , wherein the volumetric amount of the contrast agent in the fluid volume is both controllably decreased and controllably increased during the first duration of the fluid delivery procedure. 3. The method of claim 2 , wherein the volumetric amount of the flush fluid in the fluid volume is both controllably increased and controllably decreased during the first duration of the fluid delivery procedure. 4. The method of claim 1 , wherein the delivery of the contrast agent is substantially completed during the first duration. 5. The method of claim 1 , wherein the volumetric amount of the contrast agent in the fluid volume is greater than zero during the first duration of the fluid delivery procedure. 6. The method of claim 1 , further comprising: delivering a second fluid volume at a second preselected total volumetric flowrate during a second duration of the fluid delivery procedure, which is after the first duration, wherein the second fluid volume is comprised of a second volumetric amount of the flush fluid and a second volumetric amount of the contrast agent; and maintaining the second preselected total volumetric flowrate throughout the second duration of the fluid delivery procedure. 7. The method of claim 6 , wherein the second preselected total volumetric flowrate is substantially the same as the first preselected total volumetric flowrate. 8. The method of claim 6 , wherein the second fluid volume consists entirely of the flush fluid. 9. The method of claim 6 , wherein the second duration of the fluid delivery procedure immediately follows the first duration of the fluid delivery procedure. 10. The method of claim 9 , wherein the fluid delivery procedure is substantially completed during the second duration. 11. The method of claim 1 , further comprising: delivering a second fluid volume at a second preselected total volumetric flowrate during a second duration, which is after the first duration, of the fluid delivery procedure, wherein the second fluid volume is comprised of a second volumetric amount of the contrast agent and a second volumetric amount of the flush fluid; controllably varying the second volumetric amount of the contrast agent in the second fluid volume during the second duration of the fluid delivery procedure; and controllably varying the second volumetric amount of the flush fluid in the second fluid volume during the second duration of the fluid delivery procedure so as to substantially maintain the second preselected total volumetric flowrate throughout the second duration of the fluid delivery procedure. 12. The method of claim 11 , wherein the second preselected total volumetric flowrate is substantially the same as the first preselected total volumetric flowrate. 13. The method of claim 11 , wherein the second duration of the fluid delivery procedure immediately follows the first duration of the fluid delivery procedure. 14. A fluid delivery system, comprising: a fluid administration device adapted to deliver a fluid volume, wherein the fluid volume comprises a volumetric amount of a contrast agent and a volumetric amount of a flush fluid; and a controller in communication with the fluid administration device, wherein the controller comprises a processor and a non-transitory machine-readable storage medium, wherein the non-transitory machine-readable storage medium comprises instructions that, when executed by the processor, enable the fluid administration device to: deliver the fluid volume at a preselected total volumetric flowrate during a first duration of a fluid delivery procedure; controllably vary the volumetric amount of the contrast agent in the fluid volume during the first duration of the fluid delivery procedure, wherein the volumetric amount of the contrast agent is controllably increased during at least a portion of the first duration; and controllably decrease the volumetric amount of the flush fluid in the fluid volume while the volumetric amount of the contrast agent is being controllably increased so as to substantially maintain the preselected total volumetric flowrate throughout the first duration of the fluid delivery procedure. 15. The fluid delivery system of claim 14 , further comprising a source of the contrast agent and a source of the flush fluid.
in parallel, e.g. manifolds, sequencing valves (access sites A61M39/02; tube connectors A61M39/10) · CPC title
controlling delivery of multiple fluids, e.g. sequencing, mixing or via separate flow-paths (infusion of multiple fluids without using a controller A61M5/1407) · CPC title
for contrast media · CPC title
pressurised by means of pistons · CPC title
Flushing or purging · CPC title
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