Magnetic Resonance Fingerprinting (MRF) With Simultaneous Multivolume Acquisition
US-2015346300-A1 · Dec 3, 2015 · US
US10928474B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10928474-B2 |
| Application number | US-201916374961-A |
| Country | US |
| Kind code | B2 |
| Filing date | Apr 4, 2019 |
| Priority date | Apr 4, 2018 |
| Publication date | Feb 23, 2021 |
| Grant date | Feb 23, 2021 |
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In order to optimize magnetic resonance (MR) images in spin echo-based imaging, MR raw data are acquired by applying a static magnetic field, an excitation pulse, a refocusing pulse, and an RF pulse at the same time point as an echo elicited by the pulses with the result that the magnetization in the negative z-direction is deflected by a flip angle. The flip angle is selected such that, given a specified repetition time of the excitation pulse, a predetermined contrast is provided for two specified tissue types of the subject to be imaged. An MR image is reconstructed from the acquired MR raw data.
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The invention claimed is: 1. A method for obtaining raw data for reconstructing a magnetic resonance (MR) image therefrom, said method comprising: from a computer, operating an MR data acquisition scanner so as to apply a static magnetic field in a positive z-direction in the MR data acquisition scanner, which produces magnetization in the positive z-direction in an object situated in the MR data acquisition scanner; from said computer, operating said MR data acquisition scanner so as to execute a spin-echo-based MR data acquisition sequence, including applying an excitation pulse that tilts said magnetization by a predetermined angle; in said spin-echo-based sequence, applying a refocusing pulse; from said computer, operating said MR data acquisition scanner to additionally radiate an RF pulse at a time of an echo caused by said excitation and refocusing pulses, which deflects said magnetization in a negative z-direction by a flip angle; and in said computer, specifying a repetition time of said excitation pulse, and setting said flip angle, for the specified repetition time, so as to produce a predetermined contrast for two predetermined tissue types of the subject. 2. A method as claimed in claim 1 wherein said predetermined contrast is a maximum contrast. 3. A method as claimed in claim 1 comprising setting said flip angle dependent on said repetition time so that said predetermined contrast is independent of said repetition time. 4. A method as claimed in claim 1 comprising, from said computer, operating said MR data acquisition scanner to radiate at least one further refocusing pulse, preceding said refocusing pulse. 5. A method as claimed in claim 1 comprising, from said computer, operating said MR data acquisition scanner to execute said spin-echo-based sequence for T1 imaging. 6. A method as claimed in claim 1 wherein said two predetermined tissue types of the subject are white and gray brain tissue, and wherein said contrast is a gray/white contrast. 7. A method as claimed in claim 1 wherein said predetermined contrast is a maximum contrast calculated using a phase graph algorithm. 8. A method as claimed in claim 1 comprising applying said static magnetic field with a field strength of at least 3 T. 9. A method as claimed in claim 1 comprising setting said repetition time to be in a range between 500 and 2,000 ms. 10. A method as claimed in claim 1 comprising, from said computer, operating said MR data acquisition scanner to radiate said excitation pulse so as to tilt said magnetization by an excitation pulse flip angle in a range between 90°+/−45°. 11. A method as claimed in claim 1 comprising, from said computer, operating said MR data acquisition scanner to flip said magnetization with said refocusing pulse by 180°. 12. A method as claimed in claim 1 comprising, from said computer, operating said MR data acquisition scanner to radiate at least one further refocusing pulse that follows said excitation pulse and precedes said refocusing pulse, with each of said refocusing pulse and said at least one further refocusing pulse flipping said magnetization by 180°. 13. A magnetic resonance (MR) apparatus for obtaining MR raw data for reconstructing an MR image therefrom, said MR apparatus comprising: an MR data acquisition scanner; a computer configured to operate said MR data acquisition scanner so as to apply a static magnetic field in a positive z-direction in the MR data acquisition scanner, which produces magnetization in the positive z-direction in an object situated in the MR data acquisition scanner; said computer being configured to operate said MR data acquisition scanner so as to execute a spin-echo-based MR data acquisition sequence, including applying an excitation pulse that tilts said magnetization by a predetermined angle; said computer being configured to operate said MR data acquisition scanner in said spin-echo-based sequence so as to apply a refocusing pulse; said computer being configured to operate said MR data acquisition scanner so as to additionally radiate an RF pulse at a time of an echo caused by said excitation and refocusing pulses, which deflects said magnetization in a negative z-direction by a flip angle; and said computer being configured to specify a repetition time of said excitation pulse, and to set said flip angle, for the specified repetition time, so as to produce a predetermined contrast for two predetermined tissue types of the subject.
Resolving the MR signals of different chemical species, e.g. water-fat imaging · CPC title
by filtering or weighting based on different relaxation times within the sample, e.g. T1 weighting using an inversion pulse · CPC title
using RF refocusing, e.g. RARE · CPC title
for optimal flip angle of RF pulses · CPC title
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