Methods and apparatus to mitigate bubble formation in a liquid

Patent metadata

Field	Value
Publication number	US-10926263-B2
Application number	US-201816107826-A
Country	US
Kind code	B2
Filing date	Aug 21, 2018
Priority date	Mar 13, 2013
Publication date	Feb 23, 2021
Grant date	Feb 23, 2021

Abstract

Methods and apparatus to mitigate bubble formation in a liquid are disclosed. An example apparatus disclosed herein includes a bottom wall, a first baffle cantilevered from the bottom wall, and a second baffle cantilevered from the bottom wall. The first baffle is spaced apart from the second baffle, and the first baffle and the second baffle are positioned radially relative to an axis of rotation of the apparatus.

First claim

What is claimed is:

1. A reagent container comprising:
a first sidewall;
a second sidewall opposite the first sidewall;
a first end wall extending between and coupled to the first sidewall and the second sidewall;
a second end wall opposite the first end wall, the second end wall extending between and coupled to the first sidewall and the second sidewall;
a bottom wall coupled to the first sidewall and the second sidewall;
a first baffle extending from the bottom wall, the first baffle spaced apart from the first sidewall and the second sidewall such that a liquid reagent in the reagent container can flow between the first baffle and the first and second sidewalls, the first baffle spaced from the first end wall a first distance;
a second baffle extending from the bottom wall, the second baffle spaced apart from the first sidewall and the second sidewall such that the liquid reagent in the reagent container can flow between the second baffle and the first and second sidewalls, the second baffle spaced from the first end wall a second distance, the second distance greater than the first distance; and
a top wall coupled to the first sidewall and the second sidewall opposite the bottom wall, an opening defined in the top wall, the opening structured to receive a pipette for extracting the liquid reagent from the reagent container, the opening spaced from the first end wall a third distance, the third distance greater than the first distance, the third distance less than the second distance.

2. The reagent container of claim 1 , wherein a central axis of the opening is parallel to and extends between first and second baffles.

3. The reagent container of claim 1 , wherein the first baffle has a c-shaped cross-section and the second baffle has a c-shaped cross-section, and wherein a concave side of the second baffle faces a convex side of the first baffle.

4. The reagent container of claim 3 , wherein the c-shaped cross-section of the second baffle has a larger radius than the c-shaped cross-section of the first baffle.

5. The reagent container of claim 4 , wherein the first and second sidewalls are nonparallel such that the reagent container has a wedge-shaped cross-section, and wherein the first end wall is curved and the second end wall is curved.

6. The reagent container of claim 1 , further including a throat extending upward from an outer surface of the top wall, the opening defined through the throat.

7. The reagent container of claim 6 , further including a cap removably coupled to the throat.

8. The reagent container of claim 1 , wherein the bottom wall has a radius of curvature and is curved away from the top wall.

9. The reagent container of claim 1 , further including the liquid reagent, the liquid reagent filing at least ninety percent of a volume defined by the reagent container.

10. The reagent container of claim 1 , further including a base configured to be coupled to a rotatable carousel of a diagnostic analyzer, the bottom wall coupled to the base.

11. A reagent container comprising:
a first sidewall;
a second sidewall opposite the first sidewall;
a first end wall coupled between the first and second sidewalls;
a second end wall coupled between the first and second sidewalls opposite the first end wall;
a bottom wall coupled to the first sidewall, the second sidewall, the first end wall, and the second end wall;
a top wall coupled to the first sidewall, the second sidewall, the first end wall, and the second end wall opposite the bottom wall, an opening defined in the top wall, the opening structured to receive a pipette for extracting a reagent liquid from the reagent container, the top wall including a crown defining an enclosed cavity extending upward from an underside of the top wall to enable the liquid reagent to flow into the cavity when the reagent container is rotated, the opening positioned adjacent the crown; and
a baffle cantilevered from the bottom wall.

12. The reagent container of claim 11 , wherein the baffle is a first baffle, the reagent container further including a second baffle, the first baffle and the second baffle being spaced apart from the first sidewall, the second sidewall, the first end wall, the second end wall, and the top wall.

13. The reagent container of claim 11 , wherein the baffle has a c-shaped cross-section, wherein a concave side of the baffle faces the first end wall, and wherein the opening in the top wall is located a first distance from the first end wall, and the crown is located a second distance from the first end wall, the second distance greater than the first distance.

14. The reagent container of claim 11 , wherein the crown includes:
a first crown sidewall toward the first end wall;
a second crown sidewall toward the second end wall; and
a crown top wall coupled to the first crown sidewall at a first end and coupled to the second crown sidewall at a second end, the first crown sidewall being angled between the crown top wall and an outer surface of the top wall.

15. The reagent container of claim 11 , wherein the crown is dome shaped.

16. The reagent container of claim 11 , wherein the baffle is a first baffle, further including a second baffle cantilevered from the bottom wall, and wherein the opening in the top wall is disposed along a vertical axis that extends between the first and second baffles.

17. The reagent container of claim 11 , wherein the top wall includes an upward extending throat around the opening.

18. The reagent container of claim 17 , further including a cap removably coupled to the throat.

19. An apparatus comprising:
a first container to store a first liquid reagent, the first container comprising:
a first sidewall;
a second sidewall opposite the first sidewall;
a first end wall extending between and coupled to the first sidewall and the second sidewall;
a second end wall opposite the first end wall, the second end wall extending between and coupled to the first sidewall and the second sidewall;
a first bottom wall coupled to the first sidewall and the second sidewall; and
a first baffle extending from the first bottom wall, the first baffle spaced apart from the first and second sidewalls such that the first liquid reagent can flow between the first baffle and the first and second sidewalls; and

a second container to store a second liquid reagent, the second container coupled with the first container, the second container comprising:
a third sidewall;
a fourth sidewall opposite the third sidewall;
a third end wall extending between and coupled to the third sidewall and the fourth sidewall;
a fourth end wall opposite the third end wall, the fourth end wall extending between and coupled to the third sidewall and the fourth sidewall;
a second bottom wall coupled to the third sidewall and the fourth sidewall; and
a second baffle extending from the second bottom wall, the second baffle spaced apart from the third and fourth sidewalls such that the second liquid reagent can flow between the second baffle and the third and fourth sidewalls,
the second end wall adjacent the third end wall separating the first liquid reagent and the second liquid reagent.

20. The apparatus of claim 19 , wherein the first and second sidewalls are exterior sidewalls of the first container and are parallel such that the first container has a rectangular cross-section, and wherein the third and fourth sidewalls are exterior sidewalls of the second container and are nonparallel such that the second container has a wedg

Assignees

• Abbott Lab

Inventors

• Luoma Ii Robert Paul
• Ochranek Brian
• Davidson Cheryl L
• Weston Bradley C

Classifications

• B01F29/34

  Constructional details of holders for the individual packages or containers · CPC title

• B01F31/201

  Holders therefor · CPC title

• B01F31/10

  with a mixing receptacle rotating alternately in opposite directions · CPC title

• B01F29/40221

  provided with baffles, plates or bars on the wall or the bottom · CPC title

• B01F29/321

  of test-tubes or the like · CPC title