Methods and compositions for inducing protective immunity against a Marburg virus infection

US10925955B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-10925955-B2
Application numberUS-201716316846-A
CountryUS
Kind codeB2
Filing dateJul 11, 2017
Priority dateJul 15, 2016
Publication dateFeb 23, 2021
Grant dateFeb 23, 2021

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

Compositions, vaccines and methods using adenovirus vectors for priming and boosting vaccinations for inducing protective immunity against a Marburg virus infection are described.

First claim

Opening claim text (preview).

The invention claimed is: 1. A method of inducing an immune response against a Marburg virus in a subject, the method comprising: a. administering to the subject a first composition comprising an immunologically effective amount of a first adenovirus vector comprising a nucleic acid encoding a first antigenic protein of a Marburg virus having the amino acid sequence of SEQ ID NO:3; and b. administering to the subject a second composition comprising an immunologically effective amount of a second adenovirus vector comprising a nucleic acid encoding a second antigenic protein of a Marburg virus; wherein steps (a) and (b) are conducted in either order. 2. The method according to claim 1 , wherein the second adenovirus vector comprises a nucleic acid encoding an antigenic protein having the amino acid sequence of SEQ ID NO: 3 or SEQ ID NO:4. 3. The method according to claim 1 , wherein the second adenovirus vector comprises a nucleic acid encoding an antigenic protein having the amino acid sequence of SEQ ID NO: 3. 4. The method according to claim 1 , wherein the adenovirus vectors are rAd26 or rAd35 vectors. 5. The method according to claim 1 , wherein step (b) is conducted 1-12 weeks after step (a).

Assignees

Inventors

Classifications

  • Immunostimulants · CPC title

  • Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein · CPC title

  • Viral vectors · CPC title

  • viral genome or elements thereof as genetic vector · CPC title

  • characterised by the dose, timing or administration schedule · CPC title

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Frequently asked questions

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What does patent US10925955B2 cover?
Compositions, vaccines and methods using adenovirus vectors for priming and boosting vaccinations for inducing protective immunity against a Marburg virus infection are described.
Who is the assignee on this patent?
Janssen Vaccines & Prevention Bv
What technology area does this patent fall under?
Primary CPC classification A61K39/12. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Feb 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).