Ametropia treatment tracking methods and system

Patent metadata

Field	Value
Publication number	US-10912456-B2
Application number	US-201815952335-A
Country	US
Kind code	B2
Filing date	Apr 13, 2018
Priority date	Jan 27, 2016
Publication date	Feb 9, 2021
Grant date	Feb 9, 2021

Abstract

A system, method and computer program product for estimating future axial elongation of an individual's eye as a way to predict and track refractive error progression of an individual. The method includes: receiving, via a computer interface, data relating to refractive change in a prior pre-determined time period for the individual from a reference timepoint; receiving data representing an age of the individual and data representing a current axial length value of the eye as measured at the reference timepoint; calculating, by said processor, a future axial elongation of the eye as a function of the age of the individual, the current axial length value of the eye as measured at the reference timepoint, and the refractive change in the prior pre-determined time period; generating, an output indication of said computed axial elongation of the eye, and using said output indication to select a myopia control treatment for said individual.

First claim

What is claimed is:

1. A computer-implemented method for treating myopia of an individual comprising:
receiving, via an interface at a computer, data relating to refractive change in a prior pre-determined time period for the individual from a prior date to a current date, the current date being a reference timepoint;
receiving, via the interface, data representing an age of the individual and data representing a current axial length value of the eye of the individual as measured at the reference timepoint;
predicting and calculating, by a processor of said computer, a future axial elongation of the eye of the individual represented by a numerical value as a function of the age of the individual, the current axial length value of the eye of the individual as measured at the reference timepoint, and said refractive change in the prior pre-determined time period;
generating, an output indication of said predicted future axial elongation of the eye of the individual via the interface including said numerical value, and
using said output indication to select a myopia control treatment for said individual.

2. The computer-implemented method of claim 1 , further comprising:
calculating, from said past refractive changes data, a progression rate of change of refractive changes for the individual; and
annualizing the computed rate of change to obtain the refractive change for a past year.

3. The computer-implemented method of claim 1 , wherein said myopia control treatment comprises a myopia control ophthalmic lens, an orthokeratology or a pharmaceutical treatment regime.

4. The computer-implemented method of claim 3 , wherein the myopia control ophthalmic lens comprises a myopia control contact lens.

5. The computer-implemented method of claim 1 , further comprising:
comparing, by said processor, the calculated predicted future axial elongation of the eye of the individual against a predetermined threshold value; and
said processor identifying said individual to be a fast progressor when said calculated axial elongation of the eye is greater than said predetermined threshold value.

6. The computer-implemented method of claim 5 , wherein said predetermined threshold value is about 0.301 mm/yr.

7. The computer-implemented method of claim 2 , wherein said calculated predicted axial elongation of the eye is a value ΔAL, said method comprising calculating ΔAL according to:
Δ AL=a ×RECIPY (D)− b ×age+ c ×axial length− d

wherein a, b and c are respective coefficients; d is a constant value in mm, RECIPY represents said refractive change in Diopters (D), age represents an individual's age in years, and axial length is in mm.

8. The computer-implemented method of claim 7 , wherein a=−0.12051+/−0.05162 (mm/D); coefficient value b=0.03954+/−0.00323 (mm/yr); coefficient value c=0.036819+/−0.001098; and value d=0.35111 (mm)+/−0.025809.

9. A computer system for treating myopia of an individual comprising: a memory for storing instructions; and
a processor coupled to the memory, said processor running said stored instructions to:
receive, via an interface at the server, data relating to refractive change in a prior pre-determined time period for the individual from a prior date to a current date, the current date being a reference timepoint;
receive, via the interface, data representing an age of the individual and data representing a current axial length value of the eye as measured at the reference timepoint;
predict and calculate a future axial elongation of the eye represented by a numerical value as a function of the age of the individual, the current axial length value of the eye as measured at the reference timepoint, and said refractive change in the prior pre-determined time period;
generate an output indication of said calculated predicted future axial elongation of the eye via the interface including said numerical value, and
use said output indication to select a myopia control treatment for said individual.

10. The computer system of claim 9 , wherein the stored instructions further configure the processor to:
calculate, from said past refractive changes data, a progression rate of change of refractive changes for the individual; and
annualize the computed rate of change to obtain the refractive change for a past year.

11. The computer system of claim 9 , wherein said myopia control treatment comprises one or more of: a myopia control ophthalmic lens, a myopia control contact lens, a soft contact lens, an orthokeratology or a pharmaceutical treatment regime.

12. The computer system of claim 9 , wherein said processor runs further instructions to:
compare the calculated predicted axial elongation of the eye against a predetermined threshold value; and
identify an individual to be a fast progressor when said calculated axial elongation of the eye is greater than said predetermined threshold value; and
select a myopia control treatment for said fast progressor.

13. The computer system of claim 9 , wherein said calculated predicted axial elongation of the eye is a value ΔAL, said processor running further instructions to:
calculate ΔAL according to:
Δ AL=a ×RECIPY (D)− b ×age+ c ×axial length− d

wherein a, b and c are respective coefficients; d is a constant value in mm, RECIPY represents said refractive change in Diopters, age represents an individual's age in years, and axial length is in mm.

14. The computer system of claim 13 , wherein a=−0.12051+/−0.05162 (mm/D); coefficient value b=0.03954+/−0.00323 (mm/yr); coefficient value c=0.036819+/−0.001098; and value d=0.35111 (mm)+/−0.025809.

15. A computer program product for treating myopia of an individual, the computer program product comprising a non-transitory computer readable storage medium having program instructions embodied therewith, the program instructions executable by a processor to perform a method comprising:
receiving, via an interface at a computer, data relating to refractive change in a prior pre-determined time period for the individual from a prior date to a current date, the current date being a reference timepoint;
receiving, via the interface, data representing an age of the individual and data representing a current axial length value of the eye of the individual as measured at the reference timepoint;
predicting and calculating, by said processor, a future axial elongation of the eye of the individual represented by a numerical value as a function of the age of the individual, the current axial length value of the eye as measured at the reference timepoint, and said refractive change in the prior pre-determined time period; and
generating, an output indication of said predicted future axial elongation of the eye of the individual via the interface including said numerical value, and
using said output indication to select a myopia control treatment for said individual.

16. The computer program product of claim 15 , wherein said program instructions further configure said processor to perform:
calculating, from said past refractive changes data, a progression rate of change of refractive changes for the individual; and
annualizing the computed rate of change to obtain the refractive change for a past year.

17. The computer program product of claim 15 , wherein said myopia control treatment comprises a myopia control ophthalmic lens, an orthokeratology or a pharmaceutical treatment regime.

18. The computer program product of claim 17 , wherein the myopia control ophthalmic lens comprises a myopia control contact lens.

19.

Assignees

• Johnson & Johnson Vision Care

Inventors

• Brennan Noel A
• Cheng Xu

Classifications

• G16H50/50

  for simulation or modelling of medical disorders · CPC title

• G16H50/20

  for computer-aided diagnosis, e.g. based on medical expert systems · CPC title

• G16H30/00

  ICT specially adapted for the handling or processing of medical images (computed tomography A61B6/03) · CPC title

• G16H20/40

  relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture · CPC title

• G02C2202/24

  Myopia progression prevention · CPC title