Compounds and methods for kinase modulation, and indications therefor
US-2016176865-A1 · Jun 23, 2016 · US
US10899761B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10899761-B2 |
| Application number | US-202016838383-A |
| Country | US |
| Kind code | B2 |
| Filing date | Apr 2, 2020 |
| Priority date | Sep 21, 2015 |
| Publication date | Jan 26, 2021 |
| Grant date | Jan 26, 2021 |
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Provided herein are heterocyclic compounds of Formula (I), pharmaceutical compositions containing such a compound and their therapeutic uses, methods for their preparation, intermediate compounds, pharmaceutical compositions containing such a compound, and their therapeutic uses.
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What is claimed is: 1. A method for treating an inflammatory response to a viral infection comprising administering to a subject in need thereof an effective amount of a compound of formula (II): or a pharmaceutically acceptable salt thereof, wherein R 1 is (C 1 -C 3 )alkyl. 2. A method for treating an inflammatory response to a viral infection comprising administering to a subject in need thereof an effective amount of a compound of formula: or a pharmaceutically acceptable salt thereof. 3. The method of claim 1 , wherein the inflammatory response is to a coronavirus infection. 4. The method of claim 2 , wherein the inflammatory response is to a coronavirus infection. 5. A method for treating synovial sarcoma comprising administering to a subject in need thereof an effective amount of a compound of formula (II): or a pharmaceutically acceptable salt thereof, wherein R 1 is (C 1 -C 3 )alkyl. 6. A method for treating synovial sarcoma comprising administering to a subject in need thereof an effective amount of a compound of formula: or a pharmaceutically acceptable salt thereof.
containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone · CPC title
Ortho-condensed systems · CPC title
General protective or antinoxious agents · CPC title
Antiallergic agents (antiasthmatic agents A61P11/06; ophthalmic antiallergics A61P27/14) · CPC title
Immunosuppressants, e.g. drugs for graft rejection · CPC title
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