Mobile FFR simulation

Patent metadata

Field	Value
Publication number	US-10898267-B2
Application number	US-201615760649-A
Country	US
Kind code	B2
Filing date	Sep 26, 2016
Priority date	Oct 7, 2015
Publication date	Jan 26, 2021
Grant date	Jan 26, 2021

Abstract

Stenosis information is obtained by obtaining photographic image data ( 302 ) from a displayed image of a blood vessel ( 103, 203 ) containing the stenosis. Contours of the blood vessel and the stenosis are detected and dimensions are estimated from the photographic image data. A blood vessel model is reconstructed and fractional flow reserve data is calculated using the blood vessel model.

First claim

The invention claimed is:

1. A method for obtaining stenosis information in a blood vessel comprising a stenosis, comprising:
displaying an initial image of an area of interest of a patient comprising at least the stenosis;
obtaining photographic data of the displayed initial image of the area of interest using a camera of a portable mobile device;
estimating a blood vessel size from the photographic data;
detecting contours of at least the blood vessel and the stenosis;
reconstructing a blood vessel model based on the obtained photographic image data and the detected contours;
simulating blood pressure values and blood flow values in the blood vessel proximal to and distal to the stenosis using at least the blood vessel model and the estimated blood vessel size;
calculating a fractional flow reserve value from the simulated blood pressure values and blood flow values; and
displaying the calculated fractional flow reserve value.

2. The method according to claim 1 , wherein the initial image of the area of interest was obtained by 2D or 3D medical imaging data.

3. The method according to claim 1 , wherein the blood vessel is displayed in an orientation such that an unobstructed view of the stenosis is displayed.

4. The method according to claim 1 , wherein the photographic data comprises a still image or a series of still images.

5. The method according to claim 4 , wherein the still image is manually or automatically selected from the series of still images.

6. The method according to claim 1 , wherein the photographic data comprises at least one of 1) temporal information relating to a time frame in which the photographic data was obtained, 2) positional information relating to a spatial position in which the photographic data was obtained.

7. The method according to claim 1 , wherein the blood vessel size is estimated by
detecting known structures in the photographic image data;
comparing the detected known structures to typical dimensions of the known structures; and
calculating a scale factor based on the compared dimensions.

8. The method according to claim 1 , wherein the blood vessel size is estimated or influenced by a user-defined scale factor.

9. The method according to claim 1 , wherein the contours of the blood vessel and/or the stenosis are manually determined.

10. The method according to claim 1 , wherein the contours of the blood vessel and/or the stenosis are automatically determined.

11. The method according to claim 1 , wherein the calculated fractional flow reserve value are displayed as a single value distal to the stenosis or as a color coded pressure gradient along the blood vessel.

12. The method according to claim 1 , wherein a recommendation for further investigation is displayed.

13. A portable mobile device, comprising:
a camera for obtaining photographic image data from a displayed initial image data of at least a section of a blood vessel comprising a stenosis;
a blood vessel size estimator for estimating a blood vessel size from the obtained photographic image data;
a contour determiner for detecting a contour of the blood vessel contour and of the stenosis from the obtained photographic image data;
a reconstructor for reconstructing a blood vessel model based on the obtained photographic image data and the detected contours;
a simulator for simulating blood pressure values and blood flow values in the blood vessel proximal to and distal to the stenosis using at least the blood vessel model and the estimated blood vessel size;
a calculator for calculating a fractional flow reserve value from the simulated blood pressure values and blood flow values; and
a display for displaying the calculated fractional flow reserve value or a connection to an external display for displaying the calculated fractional flow reserve value.

14. The portable mobile device according to claim 10 , wherein the portable mobile device is one of a mobile phone, a tablet computer, augmented reality glasses, a camera-equipped desktop, and laptop computer.

15. A non-transitory computer-readable medium having executable instructions stored thereon which, when executed by processing circuitry, cause the processing circuitry to perform a method for obtaining stenosis information in a blood vessel comprising a stenosis, the method comprising:
obtaining, from a portable mobile device, photographic data of a displayed initial image data of at least a section of a blood vessel comprising a stenosis;
estimating a blood vessel size from the obtained photographic image data;
detecting a contour of the blood vessel contour and of the stenosis from the obtained photographic image data;
simulating blood pressure values and blood flow values in the blood vessel proximal to and distal to the stenosis using at least the blood vessel model and the estimated blood vessel size;
calculating a fractional flow reserve value from the simulated blood pressure values and blood flow values; and
displaying the calculated fractional flow reserve value.

Assignees

• Koninklijke Philips Nv

Inventors

• Schmitt Holger
• Haase Christian
• Nickisch Hannes
• Prevrhal Sven

Classifications

• A61B5/6898 Primary

  Portable consumer electronic devices, e.g. music players, telephones, tablet computers · CPC title

• A61B6/462

  characterised by constructional features of the display · CPC title

• A61B6/4417

  related to combined acquisition of different diagnostic modalities · CPC title

• A61B5/7278

  Artificial waveform generation or derivation, e.g. synthesizing signals from measured signals · CPC title

• A61B6/503

  for diagnosis of the heart · CPC title