Reverse iontophoresis biosensing with reduced sample volumes
US-2018353748-A1 · Dec 13, 2018 · US
US10895481B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10895481-B2 |
| Application number | US-201815921267-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 14, 2018 |
| Priority date | Mar 14, 2018 |
| Publication date | Jan 19, 2021 |
| Grant date | Jan 19, 2021 |
A practical reading order for non-experts. Skip the full description unless you need deep technical detail.
What the patent document calls the invention.
A short plain-language summary of the technical disclosure.
Who owns or filed the patent and who is credited as inventor.
Filing, priority, publication, and grant dates set the timeline.
The legal scope of protection — read this for what is actually claimed.
Technology tags used to group this patent with similar filings.
Prior art links and similar publications in this corpus.
Official abstract text for this publication.
Disclosed is a method for liquid measurements including: —providing a sensor including a surface arranged to receive a liquid thereupon, an electrical heating element arranged to heat the surface, and an arrangement for measuring a temperature of the surface; —receiving liquid on the sensor surface; —heating the surface by means of the electrical heating element at a known rate while taking a plurality of temperature measurements thereof in function of time, the heating being at an absolute temperature of at least 90% of the boiling point of the liquid under ambient pressure; and—deriving a volume or a flow rate measurement related to the liquid from the electrical heating rate and the temperature measurements.
Opening claim text (preview).
The invention claimed is: 1. A method for liquid measurements relating to an unknown volume or an unknown flow rate, the method comprising: providing a sensor ( 1 ) comprising a sensor surface ( 3 ) arranged to receive a liquid ( 5 ) thereupon, an electrical heating element ( 7 ) arranged to heat said surface ( 3 ), and an arrangement ( 11 , 13 ; 7 , 15 ) for measuring a temperature of said sensor surface ( 3 ); receiving liquid ( 5 ) on said sensor surface ( 3 ); heating said sensor surface ( 3 ) by means of said electrical heating element ( 7 ) at a known rate (P) while taking a plurality of temperature measurements (T) of said sensor surface ( 3 ) in function of time (t), said heating being at an absolute temperature of at least 90% of the boiling point (T b ) of said liquid ( 5 ) under ambient pressure; deriving a volume measurement or a flow rate measurement of the unknown volume or the unknown flow rate related to said liquid ( 5 ) from said electrical heating rate (P) and said temperature measurements (T). 2. The method according to claim 1 , wherein said electrical heating element ( 7 ) is provided with a predetermined electrical current (I) from a power source ( 9 ). 3. The method according to claim 1 , wherein said temperature is measured by measuring the electrical resistance of said electrical heating element ( 7 ). 4. The method according to claim 3 , wherein said electrical resistance is measured by providing a known current (I) to said electrical heating element while measuring the voltage drop thereacross, the resistance being calculated by Ohm's Law. 5. The method according to claim 1 , wherein said heating is carried out as a series of heating pulses of predetermined duration. 6. The method according to claim 5 , wherein said predetermined duration is sufficiently long to dry said sensor surface. 7. The method according to claim 1 , wherein said heating is carried out by applying power at a predetermined rate (P) insufficient to dry said sensor surface, the flow rate measurement being derived from a steady state temperature (T) measured. 8. The method according to claim 1 , wherein said heating is carried out by applying electrical power at a rate (P) insufficient to dry said sensor surface, wherein electrical power is applied to maintain a predetermined steady state temperature (T), the flow rate measurement being derived from a measurement of said electrical power (P) applied. 9. The method according to claim 1 , wherein said deriving step derives the flow rate measurement of the unknown flow rate from said electrical heating rate (P) and said temperature measurements (T) of the sensor surface ( 3 ). 10. The method according to claim 1 , wherein said deriving step derives the volume measurement of a volume of a droplet from said electrical heating rate (P) and said temperature measurements (T) of the sensor surface ( 3 ). 11. A sensor system ( 25 ; 31 ) adapted to carry out the method of claim 1 , comprising: a sensor ( 1 ) comprising a sensor surface ( 3 ) adapted to receive a quantity ( 5 ) of fluid thereupon, said sensor ( 1 ) comprising an electrical heating element ( 7 ) arranged to be connected to a source of electrical power ( 9 ) and an arrangement for measuring temperature ( 11 , 13 ; 7 ; 15 ); a conduit ( 21 , 23 ; 37 ) adapted to collect a liquid sample and to transport said liquid sample to said sensor surface ( 3 ). 12. The sensor system ( 25 ; 31 ) according to claim 11 , wherein said arrangement for measuring temperature ( 7 , 15 ) comprises said electrical heating element ( 7 ). 13. The sensor system ( 25 ; 31 ) according to claim 11 , wherein at least a part of said conduit ( 21 , 23 ; 37 ) comprises a wicking fabric arranged to be sandwiched between said sensor ( 1 ) and a skin surface ( 33 ) of a wearer. 14. The sensor system ( 25 ; 31 ) according to claim 13 , wherein said conduit ( 21 , 23 ; 37 ) extends around a peripheral wall of said sensor ( 1 ) so as to form at least one fluid pathway leading to said sensor surface ( 3 ). 15. The sensor system ( 25 ; 31 ) according to claim 13 , further comprising a substantially impermeable cover ( 39 ) arranged to at least partially seal said sensor system ( 25 ; 31 ) to said skin surface ( 33 ). 16. The sensor system ( 25 ; 31 ) according to claim 15 , wherein said cover ( 39 ) is at least partially self-adhesive. 17. The sensor system ( 25 ; 31 ) according to claim 11 , further comprising an analysis sensor ( 19 ) in fluid communication with said conduit and arranged such that said liquid passes through said analysis sensor ( 19 ) on its way to the sensor surface ( 3 ) of the sensor ( 1 ). 18. The method according to claim 1 , wherein in said providing the sensor step, a temperature sensor is provided and in said heating said surface ( 3 ) step, the plurality of temperature measurements (T) are taken on the sensor surface ( 3 ) of the temperature sensor. 19. The method according to claim 18 , wherein in said providing the sensor step, the temperature sensor that is provided is a thermistor and in said heating said surface ( 3 ) step, the plurality of temperature measurements (T) are taken on the sensor surface ( 3 ) of the thermistor.
Related publications grouped by family.
Answers are generated from the same data shown on this page.