Filter apparatus for ostium of left atrial appendage

Patent metadata

Field	Value
Publication number	US-10893926-B2
Application number	US-201514845524-A
Country	US
Kind code	B2
Filing date	Sep 4, 2015
Priority date	Oct 27, 1999
Publication date	Jan 19, 2021
Grant date	Jan 19, 2021

Abstract

Apparatus for permanent placement across an ostium of a left atrial appendage in a patient, which includes a filtering membrane configured to extend across the ostium of the left atrial appendage. The filtering membrane has a permeable structure which allows blood to flow through but substantially inhibits thrombus from passing therethrough. The apparatus also includes a support structure attached to the filtering membrane which retains the filtering membrane in position across the ostium of the left atrial appendage by permanently engaging a portion of the interior wall of the left atrial appendage. The support structure may be radially expandable from a first configuration to a second configuration which engages the ostium or the interior wall of the left atrial appendage. The filtering membrane may define an opening therethrough that is configured to expand from a first size which inhibits the passage of thrombus therethrough to a second size which allows an interventional device, e.g., an expansion balloon, to pass therethrough, and wherein the opening is resiliently biased towards the first size.

First claim

What is claimed is:

1. A method of preventing atrial appendage thrombi from entering a blood stream comprising:
positioning a membrane over and across an ostium of an atrial appendage,
wherein a distal face of the membrane has attached thereto a self-centering cylindrical support structure sized and adapted to protrude into and to contact the ostium,
wherein the self-centering cylindrical support structure has a diameter less than a diameter of the membrane,
wherein the self-centering cylindrical support structure includes a plurality of anchoring prongs extending radially outward from a distal portion of the self-centering cylindrical support structure;
allowing the plurality of anchoring prongs of the self-centering cylindrical support structure to expand radially outward within the atrial appendage from a first radially compressed configuration to a second radially expanded configuration such that the plurality of anchoring prongs of the self-centering cylindrical support structure in the second radially expanded configuration defines an anchoring prong outer diameter which is greater than a diameter of the self-centering cylindrical support structure; and
engaging the atrial appendage with the plurality of anchoring prongs of the self-centering cylindrical support structure such that the plurality of anchoring prongs of the self-centering cylindrical support structure resist being pulled from a wall of the atrial appendage.

2. The method of claim 1 , wherein the membrane is adapted to be porous to blood and adapted to prevent thrombosis formed within the atrial appendage from leaving the atrial appendage.

3. The method of claim 2 , wherein the membrane is adapted to be infiltrated with endothelial/endocardial cells thereby providing a nonthrombogenic surface.

4. The method of claim 1 , wherein the membrane is adapted to be nonporous to blood and adapted to prevent thrombosis formed within the atrial appendage from entering a blood stream.

5. The method of claim 1 , wherein the membrane is adapted to be adhesively affixed over and across the ostium of the atrial appendage.

6. The method of claim 1 , further wherein the membrane is heparin coated.

7. The method of claim 1 , wherein each prong of the plurality of anchoring prongs includes a barbed end.

8. The method of claim 1 , wherein the self-centering cylindrical support structure is made from NITINOL™.

9. The method of claim 1 , wherein the self-centering cylindrical support structure is made from ELGILOY™.

10. The method of claim 1 , wherein the self-centering cylindrical support structure is a spring loaded expandable structure.

11. The method of claim 1 , wherein the self-centering cylindrical support structure is made from a balloon expandable material.

Assignees

• Boston Scient Scimed Inc
• Atritech Inc

Inventors

• Vantassel Robert A
• Hauser Robert G
• Schwartz Robert
• Holmes David
• Sutton Gregg S
• Borillo Thomas E
• Welch Jeffrey

Classifications

• A61F2/0105 Primary

  Open ended, i.e. legs gathered only at one side · CPC title

• A61F2/0103

  With centering means · CPC title

• A61B17/0057 Primary

  Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect (sutures A61B17/04; closing rectum or urethra near body surface A61F2/0009) · CPC title

• A61F2230/0067

  conical · CPC title

• A61F2230/0093

  Umbrella-shaped, e.g. mushroom-shaped · CPC title