Compounding device, system, kit, software, and method

Patent metadata

Field	Value
Publication number	US-10888694-B2
Application number	US-201916408440-A
Country	US
Kind code	B2
Filing date	May 9, 2019
Priority date	Apr 23, 2015
Publication date	Jan 12, 2021
Grant date	Jan 12, 2021

Abstract

An exemplary pharmaceutical compounding system and device for mixing materials from at least two distinct material sources can include a valve including a valve housing and a valve structure located within the valve housing. The valve structure can be configured to permit fluid to flow through the valve when in an open position, and can include a gravity wall wherein, when the valve structure is in the open position, fluid moving through the valve structure moves upward against a force of gravity when travelling through the valve and traversing the gravity wall.

First claim

What is claimed is:

1. A valve for use in a compounding device, comprising:
a valve housing;
a valve structure located within the valve housing and configured to permit fluid to flow through the valve when in an open position, the valve structure being rotatable about a rotational axis and with respect to the valve housing,
the valve structure includes a gravity wall wherein when the valve structure is in the open position, fluid moving through the valve structure moves upward against a force of gravity after travelling through the valve and traversing the gravity wall; and
an actuator configured to connect to a lower portion of the valve structure and to rotate the valve structure about the rotational axis between the open position and a closed position, wherein the actuator is configured to over rotate the lower portion of the valve structure beyond one of the open position and the closed position, and then return the lower portion to a respective one of the open position and the closed position during a respective one of an opening operation and closing operation of the valve structure.

2. The valve of claim 1 , wherein the lower portion of the valve structure includes a keyway located therein.

3. The valve of claim 2 , wherein
the actuator is configured to mate with the keyway in the lower portion of the valve structure and to rotate the valve structure about the rotational axis between the open position and the closed position.

4. The valve of claim 3 , wherein the actuator includes a stepper motor.

5. The valve of claim 1 , further comprising:
a second valve structure located within the valve housing and configured to permit fluid to flow through the valve when the second valve structure is in a second valve structure open position, the second valve structure being rotatable about a second rotational axis and with respect to the valve housing.

6. The valve of claim 5 , wherein the second valve structure is different in size than the valve structure.

7. The valve of claim 5 , wherein the valve housing includes a plurality of openings configured to each seat a respective one of the valve structure and second valve structure.

8. The valve of claim 1 , wherein the actuator is configured to rotate the valve structure such that during actuation of the actuator a lower surface of the valve structure located adjacent the actuator rotates at a first rate of speed and an upper portion of the valve structure located further from the actuator than the lower surface simultaneously rotates at a second rate of speed that is different from the first rate of speed during actuation of the actuator due to a flexibility characteristic of the valve structure.

9. The valve of claim 1 , wherein the valve structure includes an input aperture located at a top of the valve structure and configured such that fluid entering the valve structure flows along a downward fluid path and along the rotational axis of the valve structure;
an exit aperture defined in a peripheral side wall of the valve structure and configured such that fluid exiting the valve structure flows along an exit path that is substantially perpendicular to the rotational axis of the valve structure; and
the gravity wall is located within the valve structure and configured such that fluid travelling through the valve travels along the downward fluid path at an upstream side of the gravity wall, and travels on an upward fluid path on a downstream side of the gravity wall, wherein the upstream side and downstream side of the gravity wall are opposed to each other, and a direction of the downward fluid path is generally opposed to a direction of the upward fluid path, and wherein when the valve structure is in the open position, fluid moving through the valve structure moves upward against the force of gravity when travelling through the valve and traversing the gravity wall.

10. A valve for use with a compounding device, the compounding device including a compounder housing having a top surface and a bottom surface, the top surface configured to connect to the valve and to a plurality of pump devices, the valve comprising:
a valve housing having a bottom surface configured to be connected to the top surface of the compounder housing, the valve housing including a top surface configured to be spaced away from the top surface of the compounder housing when the valve housing is connected to the compounder housing;
a plurality of valve structures located within the valve housing and configured to permit fluid to flow through the valve when a respective one of the valve structures is in an open position, each of the valve structures being rotatable about a rotational axis and with respect to the valve housing, each rotational axis being substantially perpendicular to the top surface of the valve housing and to the top surface of the compounder housing when the valve housing is connected to the compounder housing;
each of the plurality of valve structures includes a gravity wall wherein, when the respective one of the valve structures is in the open position, fluid moving through the respective one of the valve structures moves upward against a force of gravity when travelling through the valve.

11. The valve of claim 10 , wherein the plurality of valve structures are made from a first material having a first flexibility characteristic, and the valve housing is made from a second material having a second flexibility characteristic, and the first flexibility characteristic being greater than the second flexibility characteristic, wherein the valve structures are more flexible than the valve housing.

12. The valve of claim 10 , wherein a first valve structure of the plurality of valve structures is larger in size as compared to a second valve structure of the plurality of valve structures.

13. The valve of claim 10 , wherein the bottom surface of the valve housing is parallel with the top surface of the valve housing and configured to be substantially parallel with the top surface of the compounder housing.

14. A method for operating a valve in a compounding device, comprising:
providing a valve housing;
providing a valve structure located within the valve housing and configured to permit fluid to flow through the valve when the valve structure is in an open position, the valve structure being rotatable about a rotational axis and with respect to the valve housing, the valve structure including a gravity wall wherein, when the valve structure is in the open position, fluid moving through the valve structure moves upward against a force of gravity after travelling through the valve and traversing the gravity wall;
rotating a lower portion of the valve structure to cause the lower portion of the valve structure to rotate at a first speed and an upper portion of the valve structure to rotate at a second speed different from the first speed.

15. The method for operating a valve of claim 14 , wherein rotating includes rotating the valve structure between the open position and a closed position, and further includes over rotating the lower surface of the valve housing beyond one of the open position and closed position, and then returning the lower surface to the one of the open position and closed position.

16. The method for operating a valve of claim 14 , further comprising:
providing a compounder housing.

17. The method for operating a valve of claim 14 , wherein rotating includes rotating the valve structure to the open position such that a lower surface of the valve structure arrives at the open position before an upper portion of the v

Assignees

• Braun Medical Inc

Inventors

• Konrad Jr Karl
• Janders Mike
• Pearl Aaron S

Classifications

• A61M39/22

  Valves or arrangement of valves {(A61M39/02, A61M39/0247, A61M39/16 take precedence; regulating valves in infusion systems A61M5/16881; in devices worn by the patient for the reception of urine, faeces, catamenial or other discharge, or in colostomy devices A61F5/4405)} · CPC title

• B01F2101/22

  Mixing of ingredients for pharmaceutical or medical compositions · CPC title

• B01F35/717611

  Peristaltic pumps · CPC title

• B01F33/846

  using stored recipes for determining the composition of the mixture to be produced, i.e. for determining the amounts of the basic components to be dispensed from the component receptacles · CPC title

• A61J3/00

  Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms · CPC title