Heteroaromatic compounds as BTK inhibitors

US10875852B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-10875852-B2
Application numberUS-201816160048-A
CountryUS
Kind codeB2
Filing dateOct 15, 2018
Priority dateAug 10, 2012
Publication dateDec 29, 2020
Grant dateDec 29, 2020

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

The present invention encompasses compounds of the formula (I) wherein the groups A, Cy, X1 and Y are defined herein, which are suitable for the treatment of diseases related to BTK, process of making, pharmaceutical preparations which contain compounds and their methods of use.

First claim

Opening claim text (preview).

The invention claimed is: 1. A compound selected from the group consisting of: 2. The compound according to claim 1 of formula: or a pharmaceutically acceptable salt thereof. 3. The compound according to claim 1 of formula: or a pharmaceutically acceptable salt thereof. 4. The compound according to claim 1 of formula: or a pharmaceutically acceptable salt thereof. 5. The compound according to claim 1 of formula: or a pharmaceutically acceptable salt thereof. 6. The compound according to claim 1 of formula: or a pharmaceutically acceptable salt thereof. 7. The compound according to claim 1 of formula: or a pharmaceutically acceptable salt thereof. 8. The compound according to claim 1 of formula: or a pharmaceutically acceptable salt thereof. 9. The compound according to claim 1 of formula: or a pharmaceutically acceptable salt thereof. 10. The compound according to claim 1 of formula: or a pharmaceutically acceptable salt thereof. 11. A pharmaceutical composition comprising a therapeutically effective amount of a compound according to claim 1 or a pharmaceutically acceptable salt thereof. 12. A method of treating a disease chosen from rheumatoid arthritis, systemic lupus erythromatosis, scleroderma, asthma, allergic rhinitis, allergic eczema, B cell lymphoma, multiple sclerosis, juvenile rheumatoid arthritis, juvenile idiopathic arthritis, inflammatory bowel disease, graft versus host disease, psoriatic arthritis, ankylosing spondylitis and uveitis, comprising administering to a patient a therapeutically effective amount of a compound according to claim 1 or a pharmaceutically acceptable salt thereof.

Assignees

Inventors

Classifications

  • directly linked by a ring-member-to-ring-member bond · CPC title

  • linked by a carbon chain containing alicyclic rings · CPC title

  • linked by a carbon chain containing only aliphatic carbon atoms · CPC title

  • containing three or more hetero rings · CPC title

  • linked by a carbon chain containing only aliphatic carbon atoms · CPC title

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Frequently asked questions

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What does patent US10875852B2 cover?
The present invention encompasses compounds of the formula (I) wherein the groups A, Cy, X1 and Y are defined herein, which are suitable for the treatment of diseases related to BTK, process of making, pharmaceutical preparations which contain compounds and their methods of use.
Who is the assignee on this patent?
Boehringer Ingelheim Int
What technology area does this patent fall under?
Primary CPC classification C07D401/04. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Dec 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 2 related publications on this page (citations in our corpus or others sharing the same primary CPC).