Medicament delivery device

Patent metadata

Field	Value
Publication number	US-10874804-B2
Application number	US-201815994398-A
Country	US
Kind code	B2
Filing date	May 31, 2018
Priority date	Dec 21, 2012
Publication date	Dec 29, 2020
Grant date	Dec 29, 2020

Abstract

A medicament delivery device includes a housing having proximal and distal ends; a delivery member connected to the housing; a medicament container operably arranged within the housing; a drive mechanism configured to act on the medicament container for priming and for expelling a dose of medicament; and an activator mechanism configured to interact with the drive mechanism, such that a first interaction between the activator mechanism and the drive mechanism causes the container to move toward the delivery member, in which the container is primed, and such that a subsequent interaction between the activator mechanism and the drive mechanism causes a dose of medicament to be expelled through the delivery member.

First claim

The invention claimed is:

1. A medicament delivery device, comprising:
a housing having a proximal end and a distal end;
a medicament container operably arranged within the housing;
a delivery member holder fixedly attached to the housing, the delivery member holder comprising an injection needle having a proximal pointed end and a distal pointed end;
a drive mechanism arranged within the housing and configured to act on the medicament container;
a medicament container holder movably disposed inside the housing and configured to accommodate the medicament container;
and
an activator mechanism configured to interact with the drive mechanism;
wherein the activator mechanism includes a safety member removably arranged to the distal end of the housing; and
wherein the drive mechanism, activated by the activator mechanism, moves both the medicament container and the medicament container holder toward the distal pointed end of the injection needle,
wherein removal of the safety member releases the drive mechanism to move the medicament container toward the distal pointed end of the injection needle for the distal pointed end to penetrate the medicament container.

2. The medicament delivery device of claim 1 , wherein the activator mechanism includes a rotator arranged inside the housing and operably connected to the drive mechanism and the safety member such that removal of the safety member causes rotation of the rotator which then causes the drive mechanism to move the medicament container.

3. The medicament delivery device of claim 2 , wherein a plunger rod is operably connected to the medicament container and a force member having a predetermined load force configured to act on the plunger rod; the plunger rod includes at least one first contact member; and the rotator includes at least one inner guiding member that interacts with the at least one first contact member to hold the plunger rod in either an initial state, an intermediate state, or a final state depending on a rotational angle of the rotator.

4. The medicament delivery device of claim 3 , wherein the rotator includes at least one first outer guiding member; and the safety member includes at least one second contact member configured to interact with the first outer guiding member to turn the rotator, upon removal of the safety member, a first rotational angle such that the plunger rod is released from the initial state for the force member to move the plunger rod to the intermediate state and move the medicament container toward the distal pointed end of the injection needle.

5. The medicament delivery device of claim 4 , wherein the at least one second contact member has at least one side edge in contact with the at least one first outer guiding member; and during removal of the safety member, the at least one side edge pushes the at least one first outer guiding member and rotates the rotator to release the plunger rod.

6. The medicament delivery device of claim 3 , wherein the at least one inner guiding member includes a first inner transversal and circumferential section; and the plunger rod is held in the initial state by engagement of the at least one first contact member and the first inner transversal and circumferential section.

7. The medicament delivery device of claim 6 , wherein the at least one inner guiding member further includes an inner inclined section; rotation of the rotator caused by removal of the safety member disengages the at least one first contact member and the first inner transversal and circumferential section in order for the force member to drive the plunger rod proximally to move the medicament container and also moves the at least one first contact member to act on the inner inclined section to rotate the rotator a second rotational angle.

8. The medicament delivery device of claim 7 , wherein the at least one inner guiding member further includes a second inner longitudinal section and a second inner transversal and circumferential section; and the at least one first contact member moves along the second inner longitudinal section and reaches the intermediate state when contacting and engaging the second inner transversal and circumferential section.

9. The medicament delivery device of claim 3 , wherein the medicament container includes a movable stopper in contact with the plunger rod; and during movement of the plunger rod from the initial state to the intermediate state, the plunger rod forces the stopper to move the medicament container toward the distal pointed end.

10. The medicament delivery device of claim 1 , wherein the distal pointed end is covered by a protective sheath; and the distal pointed end penetrates the protective sheath and then the medicament container when the drive mechanism moves the medicament container.

11. The medicament delivery device of claim 1 , wherein the medicament container includes a septum; and the distal pointed end penetrates the septum to create a passage to release pressure and air inside the medicament container.

12. The medicament delivery device of claim 1 , wherein the delivery member includes an injection needle assembly fixedly connected to the housing and including the injection needle and a hub accommodating the injection needle; and the distal pointed end is covered by a protective sheath and the proximal pointed end is covered by a protective sheath.

13. The medicament delivery device of claim 12 , wherein the hub includes a proximally directed ledge and a distally directed ledge; the protective sheath covering the proximal pointed end is disposed on the proximally directed ledge; and the protective sheath covering the distal pointed end is disposed on the distally directed ledge.

14. The medicament delivery device of claim 12 , further comprising:
a medicament container holder movably disposed inside the housing and configured to accommodate the medicament container; and
a delivery member holder arranged in the housing and including:
a first section configured to accommodate the hub; and
a second section configured to accommodate a neck portion of a proximal section of the medicament container holder;

wherein activating the drive mechanism moves both the medicament container and the medicament container holder until the medicament container holder contacts the delivery member holder.

15. A medicament delivery device, comprising:
a housing having a proximal end and a distal end;
a medicament container operably arranged within the housing;
a delivery member holder fixedly attached to the housing, the delivery member holder comprising an injection needle having a proximal pointed end and a distal pointed end;
a drive mechanism arranged within the housing and configured to act on the medicament container; and
an activator mechanism configured to interact with the drive mechanism, where the activator mechanism comprises a rotator that is sleeve shaped, axially fixed to the housing, rotatable relative to the housing and has an outer surface having an outer guiding member;
wherein the activator mechanism includes a safety member removably arranged to the distal end of the housing; and removal of the safety member causes the drive mechanism to move the medicament container toward the distal pointed end of the injection needle for the distal pointed end to penetrate the medicament container.

16. A medicament delivery device, comprising:
a housing having a proximal end and a distal end;
a medicament container operably arranged within the housing;
a delivery member holder fixedly attached to the housing, the delivery member holder compris

Assignees

• Carebay Europe Ltd
• Shl Medical Ag

Inventors

• Giambattista Lucio
• Bendek Antonio
• Daniel Mattias
• Karlsson Sebastian

Classifications

• A61M5/2033 Primary

  Spring-loaded one-shot injectors with or without automatic needle insertion (multishot dosing syringes A61M5/31525, needle insertion only A61M5/3287) · CPC title

• A61M5/3146

  Priming, e.g. purging, reducing backlash or clearance · CPC title

• A61M5/326

  Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user · CPC title

• A61M2005/2013

  triggering of discharging means by contact of injector with patient body · CPC title

• A61M5/3204 Primary

  Needle cap remover, i.e. devices to dislodge protection cover from needle or needle hub, e.g. deshielding devices · CPC title