Therapeutic approaches for treating Alzheimer's disease
US-9387206-B2 · Jul 12, 2016 · US
Therapeutic approaches for treating Alzheimer disease and related disorders through a modulation of synapse function
US10874644B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10874644-B2 |
| Application number | US-201916433097-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 6, 2019 |
| Priority date | Apr 29, 2008 |
| Publication date | Dec 29, 2020 |
| Grant date | Dec 29, 2020 |
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- Title
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Abstract
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Compositions and methods for the treatment of Alzheimer's disease and related disorders. More particularly, disclosed are combined therapies that modulate synapse function for treating the disease.
First claim
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The invention claimed is: 1. A method of treating Lewy body dementia, the method comprising administering to a subject in need thereof an effective amount of zonisamide, or a salt or a sustained release formulation thereof. 2. The method of claim 1 , further comprising simultaneously, separately, or sequentially administering to a subject in need thereof at least one compound selected from the group of dyphylline, tadalafil, argatroban, acamprosate, cinacalcet, terbinafine, cilostazol, baclofen, phenformin, amlodipine and sulfisoxazole, or salts or sustained release formulations thereof. 3. The method of claim 1 , further comprising simultaneously, separately, or sequentially administering to a subject in need thereof at least one drug that modulates synapse function. 4. The method of claim 1 , further comprising simultaneously, separately, or sequentially administering to a subject in need thereof at least one drug that modulates angiogenesis. 5. The method of claim 1 , further comprising simultaneously, separately, or sequentially administering to a subject in need thereof at least one drug that modulates cell stress response. 6. The method of claim 1 , wherein the effective amount of zonisamide, or a salt or sustained release formulation thereof, is formulated with a pharmaceutically acceptable carrier or excipient. 7. The method of claim 1 , wherein the effective amount of zonisamide, or a salt or sustained release formulation thereof, is repeatedly administered to the subject.
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of sulfoxy acids or sulfur analogues thereof · CPC title
X and Y being nitrogen atoms, i.e. biguanides · CPC title
condensed with carbocyclic rings or ring systems · CPC title
Drugs for disorders of the nervous system · CPC title
Anti-Parkinson drugs · CPC title
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Frequently asked questions
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- What does patent US10874644B2 cover?
- Compositions and methods for the treatment of Alzheimer's disease and related disorders. More particularly, disclosed are combined therapies that modulate synapse function for treating the disease.
- Who is the assignee on this patent?
- Pharnext
- What technology area does this patent fall under?
- Primary CPC classification A61K31/42. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Dec 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 1 related publication on this page (citations in our corpus or others sharing the same primary CPC).