Topical cosmetic compositions

Patent metadata

Field	Value
Publication number	US-10870022-B2
Application number	US-201916379188-A
Country	US
Kind code	B2
Filing date	Apr 9, 2019
Priority date	Dec 18, 2015
Publication date	Dec 22, 2020
Grant date	Dec 22, 2020

Abstract

Disclosed are compositions and methods for their use for reducing tumor necrosis factor alpha (TNF-α) and/or vascular endothelial growth factor (VEGF) production in skin cells by topically applying to skin in need thereof, a composition comprising an effective amount of Opuntia ficus - indica tuna, Opuntia ficus - indica nopales , or both, or extracts thereof, to reduce TNF-α or VEGF production in skin cells.

First claim

The invention claimed is:

1. A method of treating inflamed skin by reducing tumor necrosis factor alpha (TNF-α) or vascular endothelial growth factor (VEGF) production in skin cells, the method comprising topically applying to inflamed skin a composition comprising an aqueous extract of Opuntia ficus - indica tuna, Opuntia ficus - indica nopales , or a combination thereof, to reduce TNF-α or VEGF production in skin cells to treat the inflamed skin, wherein the composition is applied to the periorbital area of a person's face.

2. The method of claim 1 , wherein the composition comprises the aqueous extract of Opuntia ficus - indica tuna.

3. The method of claim 1 , wherein the inflamed skin is erythemic skin.

4. The method of claim 1 , wherein the inflamed skin is rosacea or psoriasis.

5. The method of claim 1 , wherein the composition comprises 0.0001 wt. % to 5 wt. % of the aqueous extract of Opuntia ficus - indica tuna, Opuntia ficus - indica nopales, or a combination thereof.

6. The method of claim 1 , wherein the composition comprises 0.0001 wt. % to 2 wt. % of the aqueous extract of Opuntia ficus - indica tuna, Opuntia ficus - indica nopales , or a combination thereof.

7. The method of claim 1 , wherein the composition comprises 0.0001 wt. % to 1 wt. % of the aqueous extract of Opuntia ficus - indica tuna, Opuntia ficus - indica nopales , or a combination thereof.

8. The method of claim 1 , wherein the composition comprises 0.0001 wt. % to 0.5 wt. % of the aqueous extract of Opuntia ficus - indica tuna, Opuntia ficus - indica nopales , or a combination thereof.

9. The method of claim 1 , wherein the composition further comprises at least 50 wt. % water.

10. The method of claim 1 , wherein the composition is applied to a fine line or wrinkle.

11. The method of claim 1 , wherein the composition does not include a hydrocarbon, a silicone fluid, an organic sunscreen, chia seed oil, an extract of common mallow, a hydrogenated polymer, and a glyceryl glucoside.

12. The method of claim 1 , wherein the composition comprises the aqueous extract of Opuntia ficus - indica nopal.

13. The method of claim 1 , wherein the composition is an emulsion.

14. The method of claim 13 , wherein the emulsion is an oil-in-water emulsion.

15. The method of claim 1 , wherein the composition is a gel.

16. The method of claim 1 , wherein the composition is a solution.

17. A method of treating inflamed skin by reducing tumor necrosis factor alpha (TNF-α) or vascular endothelial growth factor (VEGF) production in skin cells, the method comprising topically applying to inflamed skin a composition comprising an aqueous extract of Opuntia ficus - indica tuna, Opuntia ficus - indica nopales , or a combination thereof, to reduce TNF-α or VEGF production in skin cells to treat the inflamed skin, wherein the composition comprises further comprises:
60 to 70 wt. % water
butylene glycol;
cyclopentasiloxane;
hydrogenated polydecene;
dimethicone/vinyl dimethicone cross polymer;
capryl glycol;
1,2-hexanediol;
hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer;
polysorbate 20;
squalane; and
panthenol.

18. A method of treating inflamed skin by reducing tumor necrosis factor alpha (TNF-α) or vascular endothelial growth factor (VEGF) production in skin cells, the method comprising topically applying to inflamed skin a composition comprising an aqueous extract of Opuntia ficus - indica tuna, Opuntia ficus - indica nopales , or a combination thereof, to reduce TNF-α or VEGF production in skin cells to treat the inflamed skin, wherein the composition further comprises:
water;
glycerin;
acrylates/C 10-30 alkyl acrylate crosspolymer;
disodium ethylenediaminetetraacetic acid;
triethanolamine;
polydimethylsiloxane;
polymethyl methylacrylate;
glyceryl stearate;
pentylene glycol;
ethylhexyl isononanoate;
cetyl alcohol;
butyrosperum parkii butter;
Zea mays germ oil;
cetyl phosphate;
cetearyl alcohol; and
ceteareth-33.

Assignees

• Mary Kay Inc

Inventors

• Hines Michelle
• Kalahasti Geetha
• Florence Tiffany
• Gan David

Classifications

• A61Q19/08

  Anti-ageing preparations · CPC title

• A61Q19/005

  Preparations for sensitive skin · CPC title

• A61Q19/00 Primary

  Preparations for care of the skin · CPC title

• A61P17/06

  Antipsoriatics · CPC title

• A61K8/9789 Primary

  Magnoliopsida [dicotyledons] · CPC title