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Applications of desogestrel in the preparation of anti-colon cancer/breast cancer ER-negative Ah receptor-positive products
US10864220B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10864220-B2 |
| Application number | US-201515740763-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 30, 2015 |
| Priority date | Jun 30, 2015 |
| Publication date | Dec 15, 2020 |
| Grant date | Dec 15, 2020 |
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- Title
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Abstract
Official abstract text for this publication.
This invention discloses applications of desogestrel in the preparation of anti-colon cancer/breast cancer ER-negative Ah receptor-positive products. This invention provides applications for desogestrel in the preparation of products to treat colon cancer and/or breast cancer. From carrying out cancer drug repositioning for the FDA- and CFDA-approved drug desogestrel, experiments for this invention show, based on screening of non-anti-cancer drugs for various cancer cell lines (tissue types) and mutation sites, that desogestrel has a new use as an anti-colon cancer medication, thus achieving a new purpose for an old drug.
First claim
Opening claim text (preview).
What is claimed is: 1. A method for treating Dukes type C colorectal adenocarcinoma in a subject comprising administering an effective amount of desogestrel to the subject. 2. The method of claim 1 , wherein the subject's colon cancer has spread to the lymph nodes. 3. A method of inhibiting the proliferation of Dukes type C colorectal adenocarcinoma cells comprising contacting the cells with an effective amount of desogestrel. 4. A method for treating a colon cancer patient with Dukes type C colorectal adenocarcinoma, the method comprising: (a) screening the patient having colon cancer for involvement of lymph nodes; and (b) treating the patient screened in step (a) having lymph node involvement by administering an effective amount of desogestrel to the patient.
Assignees
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Classifications
specific for metastasis · CPC title
Antineoplastic agents · CPC title
- A61K31/567Primary
substituted in position 17 alpha, e.g. mestranol, norethandrolone · CPC title
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- What does patent US10864220B2 cover?
- This invention discloses applications of desogestrel in the preparation of anti-colon cancer/breast cancer ER-negative Ah receptor-positive products. This invention provides applications for desogestrel in the preparation of products to treat colon cancer and/or breast cancer. From carrying out cancer drug repositioning for the FDA- and CFDA-approved drug desogestrel, experiments for this inven…
- Who is the assignee on this patent?
- Univ Shanghai Jiaotong
- What technology area does this patent fall under?
- Primary CPC classification A61K31/567. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Dec 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).