Rotary blood pump for regulating a hemodynamic parameter successively to different target values

Patent metadata

Field	Value
Publication number	US-10857275-B2
Application number	US-201616060487-A
Country	US
Kind code	B2
Filing date	Nov 2, 2016
Priority date	Dec 14, 2015
Publication date	Dec 8, 2020
Grant date	Dec 8, 2020

Abstract

A blood pump for supporting the heart may be provided that includes: a rotor with delivery elements; a rotor drive; a pressure sensor; and a regulating device that regulates a pressure or a hemodynamic parameter by means of control of the rotor drive. The pressure and/or the hemodynamic parameter may be determined by means of one or a plurality of hemodynamic sensors and/or from operating parameters of the pump. The regulating device may be suitable for regulating a hemodynamic parameter successively, such as periodically, to different target values. Using such regulation, the blood pump may be operated in an optimized manner, and operation of the blood pump may be varied in a targeted and patient-protective manner in order to attain certain goals.

First claim

The invention claimed is:

1. A blood pump for supporting a heart, the blood pump comprising:
a rotor with delivery elements;
a rotor drive;
a pressure sensor or another hemodynamic sensor;
a regulating device configured to regulate a pressure or another hemodynamic parameter by control of the rotor drive, wherein the regulating device is configured to regulate a specific pressure parameter or another specific hemodynamic parameter successively to different target values; and
a detection device configured to detect (1) a change in the pressure per unit of time in a detection range of the pressure sensor or (2) a change in the another hemodynamic parameter per unit of time in a detection range of the another hemodynamic sensor, and the detection device further configured to determine a maximum and/or a minimum of this value in a heart cycle.

2. The blood pump according to claim 1 comprising a processing device configured to relate the determined maximum values in the changes in pressure to the adjusted target pressure parameters, in particular and to determine a quotient from the determined maximum values of the changes in pressure and the adjusted target pressure parameters.

3. The blood pump according to claim 2 , wherein the processing device is configured to determine the slope of a line that is provided by a linear relationship between the determined maximum values of the changes in pressure and the adjusted target pressure parameters.

4. The blood pump according to claim 2 , wherein the processing device is configured to determine a quotient from a difference of two or more maximum values of the changes in pressure and the target pressure parameters associated with these values.

5. The blood pump according to claim 2 , wherein the adjusted target pressure parameter is end-diastolic pressure.

6. The blood pump according to claim 1 , wherein an echocardiograph is provided for performing echocardiographic measurements and is triggered by or synchronized with changes in the control of the rotor drive.

7. The blood pump according to claim 1 , wherein the regulating device is configured to regulate to varying target values during operation of the rotor drive such that at least one prespecified feature of a temporal curve of the pressure, a flow, a motor current, or a bearing position is attained.

8. The blood pump according to claim 7 , wherein the regulating device is configured to regulate the rotor drive alternating periodically such that an opening of the aortic valve may be evidenced based on a detected signal curve and/or a hemodynamic variable or an operating parameter of the blood pump.

9. The blood pump according to claim 7 , wherein the regulating device has a first operating state that corresponds to a first operation of the blood pump and a second operating state that is configured to regulate the rotor drive for a time interval such that an opening of the aortic valve may be evidenced based on a detected signal curve and/or a hemodynamic variable or an operating parameter of the blood pump.

10. The blood pump according to claim 9 , wherein a switching device is provided that switches between the first operating state and the second operating state according to a prespecified time pattern.

11. The blood pump according to claim 1 , wherein the another hemodynamic parameter that is regulated by the regulating device is the pulsatility of a pressure difference along the blood pump or of a flow rate through the blood pump.

12. The blood pump according to claim 1 , wherein a pressure sensor, or a flow sensor is connected directly to the regulating device.

13. The blood pump according to claim 12 , wherein the pressure sensor is an absolute pressure sensor.

14. The blood pump according to claim 1 , wherein the pressure sensor device comprises two pressure sensors, of which a first is arranged in or on the blood pump and a second is arranged in a volume not connected directly to the blood pump.

15. The blood pump according to claim 1 , wherein the pressure sensor and/or the another hemodynamic sensor are configured to determine the pressure and/or the another hemodynamic parameter, and/or the regulating device is configured to determine the pressure and/or the another hemodynamic parameter from operating parameters of the blood pump.

16. The blood pump according to claim 1 , wherein the regulating device is embodied such that the pressure and/or the another hemodynamic parameter is determined by means of one or a plurality of hemodynamic sensors and/or from operating parameters of the blood pump.

17. The blood pump according to claim 1 , wherein the pressure parameter is a hemodynamic pressure parameter.

18. The blood pump according to claim 1 , wherein the regulating device is configured to use an end-diastolic pressure determined from a cyclic pressure curve in the detection range of the pressure sensor.

19. The blood pump according to claim 1 , wherein the regulating device is suitable for periodically regulating to different target values.

20. A blood pump for supporting a heart, the blood pump comprising:
a rotor with delivery elements;
a rotor drive;
a pressure sensor or another hemodynamic sensor;
a regulating device configured to regulate a pressure or another hemodynamic parameter by control of the rotor drive, wherein the regulating device is configured to regulate a specific pressure parameter or another specific hemodynamic parameter successively to different target values; and
wherein an echocardiograph for performing echocardiographic measurements is configured to be triggered by or synchronized with changes in the control of the rotor drive.

21. A blood pump for supporting a heart, the blood pump comprising:
a rotor with delivery elements;
a rotor drive;
a pressure sensor or another hemodynamic sensor;
a regulating device configured to regulate a pressure or another hemodynamic parameter by control of the rotor drive, wherein the regulating device is configured to regulate a specific pressure parameter or another specific hemodynamic parameter successively to different target values; and
wherein the regulating device is configured to regulate to varying target values during operation of the rotor drive such that at least one prespecified feature of a temporal curve of the pressure, a flow, a motor current, or a bearing position is attained.

Assignees

• Berlin Heart Gmbh

Inventors

• Granegger Marcus

Classifications

• A61M60/531

  using blood pressure data, e.g. from blood pressure sensors · CPC title

• A61M60/523

  using blood flow data, e.g. from blood flow transducers · CPC title

• A61M60/515

  Regulation using real-time patient data · CPC title

• A61M60/508

  Electronic control means, e.g. for feedback regulation · CPC title

• A61M60/216

  including a rotating member acting on the blood, e.g. impeller · CPC title