Method and device for near-infrared spectroscopy

Patent metadata

Field	Value
Publication number	US-10852231-B2
Application number	US-201716312698-A
Country	US
Kind code	B2
Filing date	Jun 25, 2017
Priority date	Jun 26, 2016
Publication date	Dec 1, 2020
Grant date	Dec 1, 2020

Abstract

The invention provides a method of analyzing a liquid sample, comprising the steps of: passing near-infrared light through the sample, wherein the light travels in metal nanoparticles-added microfiber that is immersed in the sample; obtaining spectral information across a wavelength range of about 750 nm to about 1800 nm; and qualitatively identifying, and optionally quantitatively characterizing, one or more analytes in the sample. Near-infrared spectrophotometer carry out the method is also provided by the invention.

First claim

What is claimed is:

1. A method of analyzing a liquid sample, comprising:
passing near-infrared light through the sample applied onto a polytetrafluoroethylene (PTFE) surface, wherein the light travels in a microfiber, to which metal nanoparticles have been added, wherein the microfiber has a tapered section, which is immersed in the sample;
obtaining spectral information across a wavelength range of about 750 nm to about 1800 nm; and
qualitatively identifying, and quantitatively characterizing, one or more analytes in the sample.

2. A method according to claim 1 , wherein the analyte is an aromatic amine.

3. The method according to claim 2 , wherein the sample is a droplet sample.

4. A method according to claim 1 , wherein the metal nanoparticles are gold nanoparticles with average particle size in the range from 20 to 250 nm.

5. A method according to claim 1 , wherein a tapered section of the microfiber is immersed in the sample, said tapered section having the gold nanoparticles on its surface.

6. A method according to claim 5 , wherein the metal nanoparticles were added to the tapered section by applying a suspension of the nanoparticles onto the surface of the tapered section.

7. A near-infrared spectrophotometer comprising:
a light source generating near-infrared light to be guided through optic microfiber having metal nanoparticles-added section, wherein said section of the microfiber has a tapered configuration, a sample holder comprising a polytetrafluoroethylene (PTFE) surface for providing an interface between a sample and said metal nanoparticles-added tapered section of microfiber and analysis unit producing the spectral information.

8. A near-infrared spectrophotometer according to claim 7 , wherein the tapered section of the microfiber is provided with gold nanoparticles on its surface.

Assignees

• B G Negev Technologies & Applications Ltd At Ben Gurion Univ
• B G Negev Technologies And Applications Ltd At Ben Gurion Univ

Inventors

• Karabchevsky Alina

Classifications

• G01N21/3577

  for analysing liquids, e.g. polluted water · CPC title

• G01J3/10

  Arrangements of light sources specially adapted for spectrometry or colorimetry · CPC title

• G01N21/359 Primary

  using near infrared light · CPC title