Smart valved holding chamber

Patent metadata

Field	Value
Publication number	US-10850050-B2
Application number	US-201715600039-A
Country	US
Kind code	B2
Filing date	May 19, 2017
Priority date	May 19, 2016
Publication date	Dec 1, 2020
Grant date	Dec 1, 2020

Abstract

A medication delivery system having a holding chamber capable of delivering dosages of medicament from a metered dose inhaler. The holding chamber includes an actuator detector, flow detector and display. In another embodiment, a medication delivery system includes a holding chamber having an input and an output end, a metered dose inhaler operably coupled to the input end of the holding chamber, and a metered dose inhaler identifier associated with the holding chamber and operable to identify the metered dose inhaler coupled to the holding chamber.

First claim

The invention claimed is:

1. A medication delivery system comprising:
a valved holding chamber comprising a chamber housing having an input end and an output end, wherein the chamber housing defines an interior space, and wherein the output end defines an inhalation flow channel and comprises a user interface;
a valve assembly coupled to the output end and defining an exhalation path separate from the inhalation flow channel and not including the interior space of the chamber housing, the valve assembly comprising a one-piece valve having a one-way inhalation valve portion and a one-way exhalation valve portion, wherein the inhalation and exhalation valve portions are directly connected, wherein the inhalation valve portion is disposed in the inhalation flow channel and the exhalation valve portion is disposed in the exhalation path, wherein the inhalation valve portion is moveable between closed and open configurations in response to a flow from the input end, through the interior space, through the inhalation flow channel, past the inhalation valve portion and then out through the user interface, and wherein the exhalation valve portion is moveable between first and second configurations in response to an exhalation flow through the exhalation path, wherein the inhalation valve portion is reconfigurable between a first condition and a second condition in response to a stimulus, and wherein the inhalation valve portion has a first resistance to moving between the closed and open configurations when the inhalation valve portion is in the first condition, and wherein the inhalation valve portion has a second resistance to moving between the closed and open configurations when the inhalation valve portion is in the second condition, wherein the first resistance is less than the second resistance, and wherein the inhalation valve portion prevents any back flow through the flow channel during exhalation when the inhalation valve portion is in the closed configuration.

2. The medication delivery system of claim 1 wherein the first and second conditions are first and second stiffnesses.

3. The medication delivery system of claim 1 wherein the stimulus is an electrical stimulus, and further comprising an actuator adapted to apply the electrical stimulus.

4. The medication delivery system of claim 3 wherein the valve comprises an electroactive polymer.

5. The medication delivery system of claim 3 wherein the inhalation valve portion comprises an annular donut valve having an annular flange defining a central opening, wherein the annular flange engages a valve seat when the inhalation valve portion is in the closed configuration and wherein the inhalation valve portion is configured with a plurality of embedded electroactive polymer strips.

6. The medication delivery system of claim 3 wherein the inhalation valve portion comprises a duckbill valve comprising opposing flaps, wherein at least one of the flaps is configured with an embedded electroactive polymer portion.

7. The medication delivery system of claim 1 wherein the exhalation valve portion is reconfigurable between a first condition and a second condition in response to a second stimulus, and wherein the exhalation valve portion has a first resistance to moving between the first and second configurations when the exhalation valve portion is in the first condition, and wherein the exhalation valve portion has a second resistance to moving between the first and second configurations when the exhalation valve portion is in the second condition, wherein the first resistance of the exhalation valve portion is less than the second resistance of the exhalation valve portion.

8. The medication delivery system of claim 7 wherein the first and second configurations of the exhalation valve portion comprise closed and open configurations respectively.

9. The medication delivery system of claim 7 wherein the first and second conditions of the exhalation valve portion are first and second stiffnesses of the exhalation valve portion.

10. The medication delivery system of claim 7 wherein the second stimuli is a second electrical stimulus, and further comprising a second actuator adapted to apply the second electrical stimulus.

11. The medication delivery system of claim 1 wherein the user interface comprises a mouthpiece.

12. A method of using a medication delivery system comprising:
creating a flow from an interior space of a valved holding chamber housing through a flow channel at an output end of the valved holding chamber housing, wherein a valve assembly is coupled to the housing adjacent the output end and defines an exhalation path separate from the flow channel, the valve assembly comprising a one-piece valve having a one-way inhalation valve portion disposed in the flow channel and a one-way exhalation valve portion disposed in the exhalation path, wherein the inhalation and exhalation valve portions are directly connected;
moving the inhalation valve portion configured in a first condition between first and second configurations in response to the flow through the flow channel;
applying a stimulus to the inhalation valve portion;
reconfiguring the inhalation valve portion from the first condition to a second condition in response to the stimulus while the valve is in the first configuration;
restricting the flow through the flow channel with the inhalation valve portion in the second condition; and
exhaling through the exhalation path, preventing exhaled air from entering the flow channel with the inhalation valve portion, and moving the exhalation valve portion with the exhaled air.

13. The method of claim 12 wherein the first and second configurations comprise closed and open configurations respectively.

14. The method of claim 12 wherein the first and second conditions are first and second stiffnesses.

15. The method of claim 12 wherein applying the stimulus comprises applying an electrical stimulus with an actuator.

16. The method of claim 15 wherein the inhalation valve portion comprises an electroactive polymer.

17. The method of claim 15 wherein the inhalation valve portion comprises an annular donut valve having an annular flange defining a central opening, wherein the annular flange engages a valve seat when the inhalation valve portion is in the first configuration, and wherein the inhalation valve portion is configured with a plurality of embedded electroactive polymer strips.

18. The method of claim 15 wherein the inhalation valve portion comprises a duckbill valve comprising opposing flaps, wherein at least one of the flaps is configured with an embedded electroactive polymer portion.

19. The method of claim 12 wherein restricting the flow through the flow channel with the inhalation valve portion comprises ensuring that the flow rate of the flow does not exceed 30 L/min.

Assignees

• Alizoti Neritan
• Costella Stephen
• Engelbreth Daniel
• Gulka Noel
• Kirchner Alanna
• Meyer Adam
• Morton Robert
• Nowak Bart
• Romanczuk Greg
• Sakaria Ronak
• Trudell Medical Int

Inventors

• Alizoti Neritan
• Costella Stephen
• Engelbreth Daniel
• Gulka Noel
• Kirchner Alanna
• Meyer Adam
• Morton Robert
• Nowak Bart
• Romanczuk Greg
• Sakaria Ronak

Classifications

• A61M2230/40

  Respiratory characteristics · CPC title

• A61M2205/3375

  Acoustical, e.g. ultrasonic, measuring means · CPC title

• A61M2205/3368

  Temperature · CPC title

• A61M2205/3334

  Measuring or controlling the flow rate · CPC title

• A61M2205/3331

  Pressure; Flow · CPC title