Puncture injection instrument

Patent metadata

Field	Value
Publication number	US-10850045-B2
Application number	US-201615283563-A
Country	US
Kind code	B2
Filing date	Oct 3, 2016
Priority date	Apr 3, 2014
Publication date	Dec 1, 2020
Grant date	Dec 1, 2020

Abstract

A puncture injection instrument including a hollow needle body including a substrate having a first surface and a second surface opposite to the first surface, the hollow needle body having one or more projections which are formed on the first surface and each have a through hole penetrating from a distal end of the projection to the second surface of the substrate, and one or more probes positioned outside a region where the one or more projections are formed. The one or more probes include an ultrasound probe or an optical coherence tomography probe.

First claim

What is claimed is:

1. A puncture injection instrument, comprising:
a hollow needle body comprising a substrate and at least one projection formed on a first surface of the substrate such that the hollow needle body has a through hole penetrating from a distal end of the projection to a second surface of the substrate on an opposite side with respect to the first surface;
a holder detachably supporting the hollow needle body and having an injection channel formed through the holder such that the hollow needle body is mounted on one end of the holder and that the injection channel is connected to discharge liquid to the through hole of the hollow needle body; and
a probe comprising an ultrasound probe or an optical coherence tomography probe and positioned along the hollow needle body in a direction of the projection extending from the substrate such that the probe detects information of a skin to be punctured by the projection of the hollow needle body mounded on the holder and sends the information to a sensor body,
wherein the information of the skin includes at least one of a thickness of the skin and a site of a blood vessel under the skin, and the holder is configured to form a chamber between the second surface of the substrate and an end surface of a portion of the holder such that the chamber is connected to the injection channel of the holder and the through hole of the hollow needle body.

2. The puncture injection instrument of claim 1 , wherein the holder is configured to support the probe.

3. The puncture injection instrument of claim 1 , wherein the probe comprises an ultrasound probe which has a frequency range in which a center frequency is higher than 15 MHz and lower than 80 MHz.

4. The puncture injection instrument of claim 2 , wherein the probe comprises an ultrasound probe which has a frequency range in which a center frequency is higher than 15 MHz and lower than 80 MHz.

5. The puncture injection instrument of claim 1 , wherein the probe comprises a plurality of ultrasound probes or optical coherence tomography probes.

6. The puncture injection instrument of claim 2 , wherein the probe comprises a plurality of ultrasound probes or optical coherence tomography probes.

7. The puncture injection instrument of claim 3 , wherein the probe comprises a plurality of ultrasound probes or optical coherence tomography probes.

8. The puncture injection instrument of claim 4 , wherein the probe comprises a plurality of ultrasound probes or optical coherence tomography probes.

9. The puncture injection instrument of claim 1 , wherein the probe comprises an ultrasound probe including an acoustic lens.

10. The puncture injection instrument of claim 2 , wherein the probe comprises an ultrasound probe including an acoustic lens.

11. The puncture injection instrument of claim 3 , wherein the probe comprises an ultrasound probe including an acoustic lens.

12. The puncture injection instrument of claim 4 , wherein the probe comprises an ultrasound probe including an acoustic lens.

13. The puncture injection instrument of claim 5 , wherein the probe comprises an ultrasound probe including an acoustic lens.

14. The puncture injection instrument of claim 1 , wherein the hollow needle body comprises a material having biocompatibility.

15. The puncture injection instrument of claim 1 , wherein the holder comprises a cylindrical part configured to accommodate the hollow needle body inside the cylindrical part, and a columnar part configured to be mounted inside the cylindrical part such that the chamber is formed inside the cylindrical part between the second surface of the substrate and an end surface of the columnar part forming the end surface of the portion of the holder.

16. The puncture injection instrument of claim 1 , wherein the at least one projection of the hollow needle body comprises a plurality of projections formed on the first surface of the substrate such that each of the projections has the through hole penetrating from a distal end of a respective one of the projections to the second surface of the substrate.

17. The puncture injection instrument of claim 1 , further comprising:
a liquid-tight member positioned in the chamber of the holder between the second surface of the substrate and the end surface of the portion of the holder such that the liquid-tight member is surrounding an opening of the through hole on the second surface of the substrate.

18. The puncture injection instrument of claim 1 , wherein the hollow needle body has an inward flange, and the holder comprises a cylindrical part configured to accommodate the hollow needle body inside the cylindrical part and engage with the inward flange of the hollow needle body, and a columnar part configured to be mounted inside the cylindrical part such that the first surface of the substrate is positioned at an end of the cylindrical part and that the chamber is formed inside the cylindrical part between the second surface of the substrate and an end surface of the columnar part forming the end surface of the portion of the holder.

19. The puncture injection instrument of claim 1 , further comprising:
a liquid-tight member positioned in the chamber of the holder between the second surface of the substrate and the end surface of the portion of the holder such that the liquid-tight member is surrounding an opening of the through hole on the second surface of the substrate,
wherein the holder comprises a cylindrical part configured to accommodate the hollow needle body inside the cylindrical part, and a columnar part configured to be mounted inside the cylindrical part such that the chamber is formed inside the cylindrical part between the second surface of the substrate and an end surface of the columnar part forming the end surface of the portion of the holder.

20. The puncture injection instrument of claim 1 , further comprising:
a cylindrical body accommodating the holder and the hollow needle body mounted on the holder inside the cylindrical body, and supporting the probe positioned along the holder in the direction of the projection extending from the substrate.

Assignees

• Toppan Printing Co Ltd

Inventors

• Kodama Yoshihiro
• Sumida Tomoya

Classifications

• A61B8/0858 Primary

  involving measuring tissue layers, e.g. skin, interfaces · CPC title

• A61M5/46

  having means for controlling depth of insertion · CPC title

• A61M2037/0061

  Methods for using microneedles · CPC title

• A61B5/441

  Skin evaluation, e.g. for skin disorder diagnosis · CPC title

• A61M5/3295 Primary

  Multiple needle devices, e.g. a plurality of needles arranged coaxially or in parallel · CPC title