Flow balancing devices, methods, and systems

Patent metadata

Field	Value
Publication number	US-10835657-B2
Application number	US-201916381354-A
Country	US
Kind code	B2
Filing date	Apr 11, 2019
Priority date	Oct 10, 2014
Publication date	Nov 17, 2020
Grant date	Nov 17, 2020

Abstract

The disclosed subject matter relates to extracorporeal blood processing or other processing of fluids. Volumetric fluid balance, a required element of many such processes, may be achieved with multiple pumps or other proportioning or balancing devices which are to some extent independent of each other. This need may arise in treatments that involve multiple fluids. Safe and secure mechanisms to ensure fluid balance in such systems are described.

First claim

The invention claimed is:

1. A system for regulating a balanced flow of fluids, comprising:
a fluid circuit including
a first fluid channel,
a second fluid channel, the first and second fluid channels being connectable to a fluid handling device,
at least one respective peristaltic pump for each of said first and second fluid channels; and

a controller connected to the respective peristaltic pumps and configured to control a rate of pumping of one or more of said respective peristaltic pumps, the controller being connected to one or more valves and configured to establish fluid flows in the first and second fluid channels,
the controller further configured to control a ratio of flow rates entering and leaving the fluid handling device to effect a predefined net transfer of fluid to or from the fluid handling device responsively to calibration data accessible to said controller,
the controller further configured to, at selected times, temporarily establish one or more calibration flow paths in said fluid circuit, the calibration flow paths communicating respectively with ones of said first and second fluid channels to cause flow through a flow measurement component that generates a signal indicating a flow rate or relative flow rate generated by said respective peristaltic pumps,
the controller further configured to sample the signal and in response to resulting samples to adjust said calibration data,
the controller further configured to, using the adjusted calibration data, adjust the one or more of said respective peristaltic pumps in order to effect said predefined net transfer of fluid to or from the fluid handling device, and
the controller being configured to determine the selected times responsively to detection of a number of rotations of one or more of the respective peristaltic pumps.

2. The system of claim 1 , wherein
said controller is connected to receive a local pressure signal upstream and downstream of at least one of said respective peristaltic pumps, and said controller is configured to adjust the calibration data responsively to said samples and said local pressure signal upstream and downstream of at least one of said respective peristaltic pumps.

3. The system of claim 2 , wherein the calibration flow paths include one through a test flow branch that directly connects ones of said first and second fluid channels.

4. The system of claim 2 , wherein the calibration flow paths include one through a test flow branch that directly connects ones of said first and second fluid channels.

5. The system of claim 1 , wherein the calibration flow paths include one through a test flow branch that directly connects ones of said first and second fluid channels.

6. The system of claim 5 , wherein the controller is further configured to control a valve that selectively permits flow through said test flow branch and said controller is configured to automatically establish a continuous flow and sample the signal.

7. The system of claim 1 , wherein the fluid handling device is a blood treatment device.

8. The system of claim 7 , wherein the blood treatment device is a dialyzer or a hemofilter and replacement fluid source.

Assignees

• Nxstage Medical Inc

Inventors

• Burbank Jeffrey H
• Treu Dennis M
• Rubery Jr Daniel J
• Newell Scott W
• Brugger James M
• Schnell William J
• Weigel William K
• White Steven A
• Wyeth Mark T
• James Jerome
• Desouza David
• Turk Jr Joseph E
• Casey Garrett

Classifications

• A61M1/3607

  Regulation parameters · CPC title

• A61M1/34

  Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration · CPC title

• A61M1/3434

  with pre-dilution and post-dilution · CPC title

• A61M2205/502

  User interfaces, e.g. screens or keyboards · CPC title

• A61M1/3448

  by mechanically linked pumps in both ultra-filtrate and substitution flow line · CPC title