In-vitro optical transmittance test of LED on oral tissue

Patent metadata

Field	Value
Publication number	US-10823666-B2
Application number	US-201716470717-A
Country	US
Kind code	B2
Filing date	Dec 15, 2017
Priority date	Dec 19, 2016
Publication date	Nov 3, 2020
Grant date	Nov 3, 2020

Abstract

A method for determining a transmittance of light on oral tissue is provided, comprising: providing an LED; directing light from the LED onto a sample of oral tissue; measuring a first power of the light at a first surface of the sample; measuring a second power of the light at a second surface of the sample; computing surface loss of the light; and determining the transmittance of the light using the first power, the second power, and the surface loss.

First claim

We claim:

1. A method for determining a transmittance of light on tissue, comprising:
providing a light source;
directing light from the light source onto a sample of tissue;
measuring a first power of the light at a first surface of the sample;
measuring a second power of the light at a second surface of the sample;
computing a surface loss of the light; and
determining the transmittance of the light using the first power, the second power, and the surface loss.

2. The method of claim 1 , wherein the transmittance of light is represented by an attenuation coefficient in the Beer-Lambert law.

3. The method of claim 2 , wherein determining the transmittance includes computing the transmittance according to

T
=

∅
T

∅
0

=

(

1
-
r

)

⁢

e

-
α

⁢

⁢
l

where T is the transmittance without the surface loss, Ø T is a radiant flux of the second power of the light at the second surface of the sample, Ø 0 is an incoming radiant flux, r is the surface loss rate, α is the attenuation coefficient, and l is a thickness of the sample.

4. The method of claim 3 , wherein the first surface of the sample is directed toward the light source and the second surface of the sample is directed away from the light source.

5. The method of claim 1 , wherein the light source is one of an LED or a laser.

6. The method of claim 1 , wherein the tissue is oral tissue.

7. The method of claim 1 , wherein directing light from the light source includes directing light having a wavelength between about 420 nm and about 1050 nm.

8. A system for determining a transmittance of light on tissue, comprising:
a light source that emits light;
a wavelength meter having an input window, the wavelength meter being configured to measure a first power of the emitted light at a first surface of a sample of the tissue positioned at the input window and a second power of the emitted light at a second surface of the sample; and
a controller coupled to the wavelength meter, the controller being configured to collect data to compute a surface loss rate of the emitted light onto the sample and to determine the transmittance of the emitted light into the sample using the first power, the second power and the surface loss rate.

9. The system of claim 8 , further comprising a spectroscope having an input to receive light from the light source and output that emits the emitted light at a desired wavelength.

10. The system of claim 9 , wherein the light source is one of an LED or a laser that emits light at a wavelength below about 1050 nm.

11. The system of claim 8 , wherein the controller computes the transmittance according to

T
=

∅
T

∅
0

=

(

1
-
r

)

⁢

e

-
α

⁢

⁢
l

where T is the transmittance without the surface loss, Ø T is a radiant flux of the second power of the light at the second surface of the sample, Ø 0 is an incoming radiant flux, r is the surface loss rate, α is an attenuation coefficient, and l is a thickness of the sample.

12. The system of claim 8 , wherein the first surface of the sample is directed toward the light source and the second surface of the sample is directed away from the light source.

Assignees

• Univ Indiana Res & Tech Corp

Inventors

• Chen Jie
• Jiang Feifei

Classifications

• A61N2005/0659

  infrared · CPC title

• A61N5/0603

  for treatment of body cavities · CPC title

• G01N21/31 Primary

  Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry {(G01N21/72 takes precedence)} · CPC title

• G01N21/59

  Transmissivity (G01N21/25 takes precedence) · CPC title

• A61B5/0059

  using light, e.g. diagnosis by transillumination, diascopy, fluorescence (photoacoustic A61B5/0093; optical measurement of heart rate A61B5/02416; optical measurement of blood flow A61B5/0261; optical measurement of analytes A61B5/1455) · CPC title