Use of one or a combination of phyto-cannabinoids in the treatment of epilepsy
US-9522123-B2 · Dec 20, 2016 · US
US10799467B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10799467-B2 |
| Application number | US-201514685753-A |
| Country | US |
| Kind code | B2 |
| Filing date | Apr 14, 2015 |
| Priority date | Mar 30, 2010 |
| Publication date | Oct 13, 2020 |
| Grant date | Oct 13, 2020 |
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This invention relates to the use of the phytocannabinoid cannabidivarin (CBDV) and combinations of the phytocannabinoid CBDV with tetrahydrocannabivarin (THCV) and cannabidiol (CBD) in the treatment of epilepsy. The invention further relates to the use of the phytocannabinoid CBDV in combination with standard anti-epileptic drugs (SAEDs). Preferably the SAED is one of ethosuximide, valproate or phenobarbital.
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The invention claimed is: 1. A method for the treatment of partial seizures, which comprises administering to a subject in need thereof a therapeutically effective amount of the phytocannabinoid CBDV, wherein the CBDV is present as the only active cannabinoid. 2. The method of claim 1 , wherein the partial seizure to be treated is a temporal lobe seizure. 3. The method of claim 1 , wherein the CBDV is used in combination with a standard anti-epileptic drug. 4. The method of claim 3 , wherein the standard anti-epileptic drug is phenobarbital. 5. The method of claim 3 , wherein the standard anti-epileptic drug is ethosuximide. 6. The method of claim 3 , wherein the standard antiepileptic drug is valproate.
Cannabis · CPC title
o-phenolic cannabinoids, e.g. cannabidiol, cannabigerolic acid, cannabichromene or tetrahydrocannabinol · CPC title
Antiepileptics; Anticonvulsants · CPC title
Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00 · CPC title
Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca · CPC title
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