Rotor assembly including a housing for a sensor array component and methods for using same

Patent metadata

Field	Value
Publication number	US-10797567-B2
Application number	US-201615216991-A
Country	US
Kind code	B2
Filing date	Jul 22, 2016
Priority date	Jul 23, 2015
Publication date	Oct 6, 2020
Grant date	Oct 6, 2020

Abstract

A rotor assembly includes a rotor plate to rotate around a first axis, a bucket attached to the rotor plate and to rotate around a second axis, and a stop plate to rotate around the first axis between an open position and a closed position. When in the closed position, the stop plate engages the bucket to fix an angular position of the bucket relative to a plane of rotation of the rotor assembly. The rotor assembly further includes a housing for a sensor array component, the housing disposed in the bucket and including a solution inlet, a solution outlet, a transfer basin, a solution retainer disposed between the solution outlet and the transfer basin, and a collection reservoir in fluid communication with the transfer basin. The solution inlet and the solution outlet to engage ports of a flow cell of a sensor array.

First claim

What is claimed is:

1. A rotor assembly comprising:
a rotor plate to rotate around a first axis;
a bucket rotatably attached to the rotor plate and to rotate around a second axis;
a stop plate to rotate around the first axis relative to the rotor plate between an open position and a closed position, when in the closed position, the stop plate is to engage the bucket to fix an angular position of the bucket relative to a plane of rotation of the rotor assembly; and
a housing for a sensor array component, the housing disposed in the bucket, the housing including a housing body defining:
a solution inlet and a solution outlet to engage ports of a flow cell of a sensor array, the housing body defining a flow path beginning at the solution outlet;
a transfer basin defined by the housing body and in the flow path;
a solution retainer defined by the housing body and disposed between the solution outlet and the transfer basin within the flow path; and
a collection reservoir defined by the housing body in fluid communication with the transfer basin within the flow path at an opposite end of the flow path from the solution retainer.

2. The rotor assembly of claim 1 , wherein the stop plate includes a wing with a chamfered surface to engage a surface of the bucket when the stop plate is moving to the closed position.

3. The rotor assembly of claim 2 , wherein the bucket includes a chamfered surface to engage the chamfered surface of the stop plate.

4. The rotor assembly of claim 1 , wherein the rotor plate includes a rear stop surface to engage the bucket when the stop plate is in a closed position.

5. The rotor assembly of claim 1 , wherein a weight of the bucket is distributed to provide an angular position relative to a plane of rotation of the rotor assembly when the rotor assembly is spinning and the stop plate is in an open position.

6. The rotor assembly of claim 1 , wherein the solution inlet has a conical opening to receive a distal end of a pipette tip.

7. The rotor assembly of claim 1 , wherein the solution inlet and the solution outlet further include gasket material to engage the ports of the flow cell.

8. The rotor assembly of claim 1 , further comprising a cap coupled to the housing body and disposed over the transfer basin.

9. The rotor assembly of claim 8 , wherein the cap defines an opening for accessing the solution outlet.

Assignees

• Life Technologies Corp

Inventors

• Roswech Todd

Classifications

• B01L3/50273 Primary

  characterised by the means or forces applied to move the fluids · CPC title

• G01N2035/0449

  using centrifugal transport of liquid · CPC title

• B01L2400/0633

  with moving parts · CPC title

• B04B5/0421

  pivotably mounted · CPC title

• B01L3/502738

  characterised by integrated valves (throttle valves in microfluidic sample containers B01L3/502746) · CPC title