Method for providing a succinic acid solution

Patent metadata

Field	Value
Publication number	US-10793501-B2
Application number	US-201615747189-A
Country	US
Kind code	B2
Filing date	Jul 29, 2016
Priority date	Jul 31, 2015
Publication date	Oct 6, 2020
Grant date	Oct 6, 2020

Abstract

The invention pertains to a method for providing a succinic acid solution, comprising the steps of —providing a first magnesium succinate containing medium with a magnesium succinate concentration of 18-23 wt. % to a first acidification reactor where it is contacted with hydrogen chloride to form a solution of succinic acid, magnesium chloride and hydrogen chloride, —providing a second magnesium succinate containing medium with a magnesium succinate concentration of 25-50 wt. %, and contacting it in a second acidification reactor with the solution of succinic acid, magnesium chloride and hydrogen chloride withdrawn from the first acidification reactor, to form an aqueous mixture comprising magnesium chloride and succinic acid with a succinic acid concentration of at least 18 wt. %. The method according to the invention makes it possible to obtain a solution comprising succinic acid and magnesium 20 chloride with an increased succinic acid concentration.

First claim

The invention claimed is:

1. A method for providing a succinic acid solution, comprising the steps of:
contacting a first magnesium succinate containing medium with a magnesium succinate concentration of 18-23 wt. % in a first acidification reactor with hydrogen chloride to form a solution of succinic acid, magnesium chloride, and hydrogen chloride, and
contacting a second magnesium succinate containing medium with a magnesium succinate concentration of 25-50 wt. % in a second acidification reactor with the solution of succinic acid, magnesium chloride, and hydrogen chloride withdrawn from the first acidification reactor, to form an aqueous mixture comprising magnesium chloride and succinic acid with a succinic acid concentration of at least 18 wt. %.

2. The method of claim 1 , wherein the first magnesium succinate containing medium and/or the second magnesium succinate containing medium are obtained by subjecting an aqueous magnesium succinate solution with a magnesium succinate concentration in the range of 5-15 wt. % to a concentration step in an evaporation reactor wherein water is evaporated to obtain a magnesium chloride solution with the specified concentration.

3. The method of claim 2 , comprising the steps of:
subjecting a magnesium succinate solution with a magnesium succinate concentration of 5-13 wt. % to at least one concentration step in at least one evaporation reactor, to obtain a first magnesium succinate containing medium with a magnesium succinate concentration of 18-23 wt. % and a second magnesium succinate containing medium with a concentration of 25-50 wt. %,
contacting the first magnesium succinate containing medium with a magnesium succinate concentration of 18-23 wt. % in a first acidification reactor with hydrogen chloride to form a solution of succinic acid, magnesium chloride, and hydrogen chloride, and
contacting the second magnesium succinate containing medium with a magnesium succinate concentration of 25-50 wt. % in a second acidification reactor with the solution of succinic acid, magnesium chloride, and hydrogen chloride withdrawn from the first acidification reactor, to form an aqueous mixture comprising magnesium chloride and succinic acid with a succinic acid concentration of at least 20 wt. %.

4. The method of claim 1 , wherein the HCl provided to the first acidification reactor is provided in gaseous form.

5. The method of claim 1 , wherein the HCl provided to the first acidification step is derived from the thermal decomposition of magnesium chloride.

6. The method of claim 1 , which further comprises the steps of:
subjecting the aqueous mixture comprising magnesium chloride and succinic acid with a succinic acid concentration of at least 18 wt. % to a precipitation step and a separation step, to generate solid succinic acid and a magnesium chloride solution,
providing the magnesium chloride solution to a thermal decomposition step at a temperature of at least 300° C., resulting in the formation of magnesium oxide and hydrogen chloride, and
providing the hydrogen chloride to the first acidification reactor, either directly in gaseous form, or after absorption into water to form a hydrogen chloride solution.

7. The method of claim 1 , comprising the steps of:
subjecting a carbon source to a fermentation step to form succinic acid, which fermentation step comprises the steps of fermenting a carbon source with a micro-organism capable of producing succinic acid in a fermentation broth to form succinic acid and neutralizing at least part of the succinic acid by adding a magnesium base selected from magnesium oxide, magnesium hydroxide, magnesium carbonate, and magnesium bicarbonate, thereby obtaining a magnesium succinate solution with a magnesium succinate concentration of 5-15 wt. %,
subjecting the magnesium succinate solution with a magnesium succinate concentration of 5-15 wt. % to at least one concentration step in at least one evaporation reactor, to obtain the first magnesium succinate containing medium with a magnesium succinate concentration of 18-23 wt. % and the second magnesium succinate containing medium with a concentration of 25-50 wt. %,
contacting the first magnesium succinate containing medium with a magnesium succinate concentration of 18-23 wt. % in a first acidification reactor with hydrogen chloride to form a solution of succinic acid, magnesium chloride, and hydrogen chloride,
contacting the second magnesium succinate containing medium with a magnesium succinate concentration of 25-50 wt. % in a second acidification reactor with the solution of succinic acid, magnesium chloride, and hydrogen chloride withdrawn from the first acidification reactor, to form the aqueous mixture comprising magnesium chloride and succinic acid with a succinic acid concentration of at least 18 wt. %,
subjecting the aqueous mixture comprising magnesium chloride and succinic acid with a succinic acid concentration of at least 18 wt. % to a precipitation step and a separation step, to generate solid succinic acid and a magnesium chloride solution,
providing the magnesium chloride solution to a thermal decomposition step at a temperature of at least 300° C., resulting in the formation of magnesium oxide and hydrogen chloride,
optionally providing the magnesium oxide as neutralising agent to the fermentation step, or after conversion to magnesium hydroxide, magnesium carbonate, or magnesium bicarbonate, and
providing the hydrogen chloride to the first acidification reactor, either directly, or after dissolution in water to form a hydrogen chloride solution.

8. The method of claim 2 , wherein both the first magnesium succinate containing medium and the second magnesium succinate containing medium are obtained by subjecting an aqueous magnesium succinate solution with a magnesium succinate concentration in the range of 5-15 wt. % to a concentration step in an evaporation reactor wherein water is evaporated to obtain a magnesium chloride solution with the specified concentration.

9. A process for the production of butanediol, comprising:
preparing solid succinic acid by the method of claim 6 ,
converting the solid succinic acid to a succinic acid ester, and
converting the succinic acid ester to the butanediol.

10. A process for the production of butanediol, comprising:
preparing solid succinic acid by the method of claim 7 ,
converting the solid succinic acid to a succinic acid ester, and
converting the succinic acid ester to the butanediol.

Assignees

• Purac Biochem Bv

Inventors

• Jansen Peter Paul
• Van Breugel Jan
• Van Bochove Gerard Hendrik
• Vidal Lancis Jose Maria
• Dekic Zivkovic Tanja

Classifications

• C01B7/03

  Preparation from chlorides · CPC title

• C12P7/40

  containing a carboxyl group {including Peroxycarboxylic acids} · CPC title

• C07C51/02 Primary

  from salts of carboxylic acids · CPC title

• C01F5/10

  by thermal decomposition of magnesium chloride with water vapour · CPC title

• C07C55/10

  Succinic acid · CPC title