Microorganism able to Produce L-Amino Acid, and Method for Producing L-Amino Acid by Using the Same
US-2015050703-A1 · Feb 19, 2015 · US
L-threonine and L-tryptophan producing bacteria strain and method of making same
US10787692B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10787692-B2 |
| Application number | US-201715465881-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 22, 2017 |
| Priority date | Jan 6, 2012 |
| Publication date | Sep 29, 2020 |
| Grant date | Sep 29, 2020 |
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- Title
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Abstract
Official abstract text for this publication.
The present invention relates to a microorganism able to produce L-threonine or L-tryptophan, and to a method for producing L-threonine or L-tryptophan by using same. More specifically, the present invention relates to: recombinant Escherichia coli which is more efficient in producing L-threonine or L-tryptophan by increasing the ability to produce ATP which is used as the most plentiful energy source in cells when producing L-threonine or L-tryptophan; and a method for producing L-threonine or L-tryptophan by using same.
First claim
Opening claim text (preview).
The invention claimed is: 1. An L-threonine or L-tryptophan producing recombinant Escherichia coli strain, wherein the strain is modified by deletion of at least one polynucleotide, wherein the polynucleotide is selected from the group consisting of SEQ ID NO: 1, SEQ ID NO: 3, and SEQ ID NO: 5. 2. The L-threonine or L-tryptophan producing recombinant Escherichia coli strain according to claim 1 , wherein the polynucleotide encodes a protein selected from the group consisting of YsaA having an amino acid sequence of SEQ ID NO: 2, a protein YdaS having an amino acid sequence of SEQ ID NO: 4, and a protein YbiX having an amino acid sequence of SEQ ID NO: 6. 3. The L-threonine or L-tryptophan producing recombinant Escherichia coli strain according to claim 1 , wherein the recombinant Escherichia coli strain is L-threonine producing Escherichia coli CA03-4257P (KCCM11243P). 4. The L-threonine or L-tryptophan producing recombinant Escherichia coli strain according to claim 1 , wherein the recombinant Escherichia coli strain is L-tryptophan producing Escherichia coli CA04-2002 (KCCM11245P). 5. A method for producing L-threonine or L-tryptophan, the method comprising culturing an L-threonine or L-tryptophan producing recombinant Escherichia coli strain, wherein the strain is modified by deletion of at least one polynucleotide, wherein the polynucleotide is selected from the group consisting of SEQ ID NO: 1, SEQ ID NO: 3, and SEQ ID NO: 5. 6. The method according to claim 5 , wherein the recombinant Escherichia coli strain is L-threonine producing Escherichia coli CA03-4257P (KCCM11243P). 7. The method according to claim 5 , wherein the recombinant Escherichia coli strain is L-tryptophan producing Escherichia coli CA04-2002 (KCCM11245P).
Assignees
Inventors
Classifications
Vectors or expression systems specially adapted for E. coli · CPC title
Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine · CPC title
- C12N1/20Primary
Bacteria; Culture media therefor · CPC title
- C07K14/245Primary
Escherichia (G) · CPC title
with 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors (1.14.11) · CPC title
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Frequently asked questions
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- What does patent US10787692B2 cover?
- The present invention relates to a microorganism able to produce L-threonine or L-tryptophan, and to a method for producing L-threonine or L-tryptophan by using same. More specifically, the present invention relates to: recombinant Escherichia coli which is more efficient in producing L-threonine or L-tryptophan by increasing the ability to produce ATP which is used as the most plentiful ener…
- Who is the assignee on this patent?
- Cj Cheiljedang Corp
- What technology area does this patent fall under?
- Primary CPC classification C12N1/20. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 1 related publication on this page (citations in our corpus or others sharing the same primary CPC).