Peristaltic micropump and related systems and methods

Patent metadata

Field	Value
Publication number	US-10781809-B2
Application number	US-201916658313-A
Country	US
Kind code	B2
Filing date	Oct 21, 2019
Priority date	Oct 7, 2010
Publication date	Sep 22, 2020
Grant date	Sep 22, 2020

Abstract

A peristaltic micropump includes one or more flexible channels configured to transfer one or more pumped fluids, and an actuator configured to engage the one or more flexible channels and rotate about a central axis. The actuator includes a plurality of rolling elements and a driving element configured such that the driving element operably rotates about the central axis and each rolling element operably rolls about a respective axis that is not parallel to the central axis. The plurality of rolling elements is disposed between the one or more flexible channels and the driving element. The driving element includes a cage configured to capture the plurality of rolling elements such that the plurality of rolling elements is located at different radii from a center of the cage.

First claim

What is claimed is:

1. A peristaltic micropump, comprising:
multiple flexible channels configured to transfer one or more pumped fluids;
an actuator configured to engage the multiple flexible channels, and rotate about a central axis, wherein the actuator comprises two or more rolling elements, each rolling element having a geometric center, and a driving element configured such that the driving element operably rotates about the central axis and each rolling element operably rolls about a respective axis that is not parallel to the central axis, wherein the two or more rolling elements are disposed between the multiple flexible channels and the driving element;
wherein the driving element comprises a cage configured to capture the two or more rolling elements such that the geometric centers of at least two of the two or more rolling elements are located at different radii having different distances from a center of the cage;
wherein the multiple flexible channels comprise multiple concentric channels located at different radii having different distances from the center of the cage; and
wherein the driving element and a surface of a bulk material that contains the multiple flexible channels have a coefficient of friction that is substantially matched to each other, and the driving element and the bulk material that contains the multiple flexible channels have a coefficient of elasticity that is substantially matched to each other.

2. The peristaltic micropump of claim 1 , wherein the driving element and the bulk material that contains the multiple flexible channels are comprised of a flexible polymeric compound.

3. The peristaltic micropump of claim 1 , wherein the driving element and the bulk material that contains the multiple flexible channels are comprised of polydimethylsiloxane (PDMS).

4. The peristaltic micropump of claim 1 , wherein each rolling element is configured to rotate about an axle.

5. The peristaltic micropump of claim 1 , wherein the two or more rolling elements comprise a plurality of ball bearings.

6. The peristaltic micropump of claim 1 , wherein the two or more rolling elements comprise a plurality of cylindrical rollers.

7. The peristaltic micropump of claim 1 , wherein the two or more rolling elements comprise a plurality of conical rollers.

8. The peristaltic micropump of claim 1 , wherein the driving element comprises a rotating drive mechanism and a centering component configured to center the cage with respect to the rotating drive mechanism.

9. The peristaltic micropump of claim 1 , wherein the multiple concentric channels are arranged in a single channel section.

10. The peristaltic micropump of claim 9 , wherein the multiple concentric channels are fluidically connected to an input node and an output node.

11. The peristaltic micropump of claim 10 , wherein each of the multiple concentric channels is fluidically connected to the input node and the output node.

12. The peristaltic micropump of claim 9 , wherein each of the multiple concentric channels is fluidically and directly connected to a respective input node and a respective output node.

13. The peristaltic micropump of claim 2 , wherein the multiple concentric channels are arranged in multiple channel sections.

14. The peristaltic micropump of claim 13 , wherein the multiple channel sections are spatially and fluidically separated from one another, and wherein channels of each channel section of the multiple concentric channels are fluidically connected to a respective input node and a respective output node.

15. The peristaltic micropump of claim 13 , wherein the multiple channel sections have a first multiple channel section and a last multiple channel section, and are spatially and fluidically connected to one another except that the first multiple channel section and the last multiple channel section are spatially and fluidically separated from one another, and wherein the first multiple channel section and the last multiple channel section are fluidically connected to an input node and an output node, respectively.

Assignees

• Univ Vanderbilt

Inventors

• Gould Parker A
• Hoang Loi T
• Schaffer David K
• Reiserer Ronald S
• Samson Philip C
• Wikswo John P

Classifications

• C12M41/48

  Automatic or computerized control (automatic analysis G01N35/00) · CPC title

• C12M23/16

  Microfluidic devices; Capillary tubes (integrated microfluidic structures B01L3/5027; microreactors B01J19/0093) · CPC title

• F04B43/1253

  by using two or more rollers as squeezing elements, the rollers moving on an arc of a circle during squeezing · CPC title

• B01L2300/123

  Flexible; Elastomeric · CPC title

• F04B43/0054

  particularities of the flexible members · CPC title