Ratchet drive for on body delivery system

Patent metadata

Field	Value
Publication number	US-10780217-B2
Application number	US-201715809491-A
Country	US
Kind code	B2
Filing date	Nov 10, 2017
Priority date	Nov 10, 2016
Publication date	Sep 22, 2020
Grant date	Sep 22, 2020

Abstract

Ratchet-based drive systems for more reliable and safer drug delivery are provided. The ratchet-based drive systems restrict angular movement and/or linear movement of components that cause a plunger to expel a liquid drug from a drug container. Movement of the components can be restricted to correspond to a predetermined or desired portion of the liquid drug. In the case that control of the drive system is lost or fails, the maximum amount of drug that could be delivered is limited to a known amount, thereby reducing the likelihood of an overdose.

First claim

What is claimed is:

1. A system, comprising: a ratchet gear; a lead screw coupled to the ratchet gear, an end of the lead screw coupled to a plunger positioned in a drug container; a ratchet carrier positioned around the ratchet gear, wherein the ratchet carrier includes an extension extending from a perimeter of the ratchet carrier; a first pawl coupled to the ratchet carrier and a second pawl coupled to the ratchet carrier, the first and second pawls configured to selectively engage the ratchet gear; and a first carrier stop configured to restrict rotation of the ratchet carrier in a first direction by stopping the extension from further rotation in the first direction; and a second carrier stop configured to restrict rotation of the ratchet carrier in a second, opposite direction by coming into contact with and stopping the extension from further rotation in the second, opposite direction.

2. The system of claim 1 , wherein the first and second pawls are configured to engage the ratchet gear when the ratchet carrier is rotated in the first direction, thereby coupling the ratchet carrier to the ratchet gear.

3. The system of claim 2 , wherein the ratchet gear and the lead screw are configured to rotate in the first direction when the ratchet carrier is rotated in the first direction.

4. The system of claim 3 , wherein the lead screw is configured to move in a linear direction when the ratchet carrier is rotated in the first direction, the linear direction parallel to an axis of rotation of the ratchet carrier.

5. The system of claim 4 , wherein the lead screw is configured to move the plunger in the linear direction and further into the drug container when the ratchet carrier is rotated in the first direction.

6. The system of claim 5 , wherein the plunger is configured to expel a portion of a liquid drug stored in the drug container when moved in the linear direction.

7. The system of claim 6 , wherein a predetermined dose of the liquid drug is expelled from the drug container when the ratchet carrier is rotated in the first direction from an initial position corresponding to the second carrier stop to a final position corresponding to the first carrier stop.

8. The system of claim 7 , wherein the first carrier stop is configured to prevent the ratchet carrier from rotating further in the first direction.

9. The system of claim 7 , wherein the first and second pawls are configured to disengage the ratchet gear when the ratchet carrier is rotated in the second direction, thereby decoupling the ratchet gear from the ratchet carrier.

10. The system of claim 9 , wherein the ratchet gear and the lead screw are configured to remain stationary when the ratchet carrier is rotated in the second direction.

11. The system of claim 9 , wherein the ratchet carrier is rotated in the second direction to return to the initial position to reset the ratchet drive system.

12. The system of claim 11 , wherein the first and second pawls are configured to re-engage the ratchet gear when the ratchet drive system is reset.

13. The system of claim 12 , further comprising a controller, the controller configured to control operation of a power source for rotating the ratchet carrier.

14. The system of claim 13 , wherein the first and second carrier stops each include a sensor configured to detect when the ratchet carrier is in the final position and the initial position, respectively.

15. The system of claim 14 , wherein each sensor is configured to transmit a signal to the controller to indicate at least one of the final position and the initial position of the ratchet carrier.

16. The system of claim 15 , wherein the controller is configured to maintain a count of a number of predetermined doses of the liquid drug that have been delivered based on the signals transmitted by the sensors.

17. A method, comprising:
rotating a ratchet carrier in a first direction from an initial position to a final position;
rotating a ratchet gear in the first direction based on rotating the ratchet carrier;
rotating a lead screw in the first direction based on rotating the ratchet gear;
moving the lead screw in a linear direction parallel to an axis of rotation of the lead screw based on rotating the lead screw, the lead screw coupled to a plunger positioned in a drug container holding a liquid drug;
moving the plunger in the linear direction further into the drug container based on moving the lead screw, thereby expelling a dose of the liquid drug from the drug container;
decoupling the ratchet carrier from the ratchet gear; and
rotating the ratchet carrier in a second direction opposite the first direction from the final position to the initial position, wherein decoupling the ratchet carrier from the ratchet gear prior to rotating the ratchet gear in the second direction prevents the ratchet gear and the lead screw from rotating in the second direction.

18. The method of claim 17 , further comprising restricting rotation of the ratchet carrier beyond the final position based on a position of a first carrier stop.

19. The method of claim 18 , further comprising detecting the final position of the ratchet carrier based on a sensor of the first carrier stop.

20. The method of claim 19 , further comprising maintaining a count of a number of doses of the liquid drug expelled based on detecting the final position of the ratchet carrier.

21. The method of claim 18 , further comprising restricting rotation of the ratchet carrier beyond the initial position based on a position of a second carrier stop.

22. The method of claim 21 , further comprising detecting the initial position of the ratchet carrier based on a sensor of the second carrier stop.

Assignees

• Insulet Corp

Inventors

• Nazzaro David
• Kozin Simon
• Mccaffrey Maureen

Classifications

• A61M5/16804

  Flow controllers · CPC title

• A61M5/16877

  Adjusting flow; Devices for setting a flow rate · CPC title

• A61M5/31536

  Blocking means to immobilize a selected dose, e.g. to administer equal doses · CPC title

• A61M2005/3154

  limiting maximum permissible dose · CPC title

• A61M5/1452 Primary

  pressurised by means of pistons · CPC title