High pressure fitting for supercritical fluid chromatography

Patent metadata

Field	Value
Publication number	US-10774957-B2
Application number	US-201816049483-A
Country	US
Kind code	B2
Filing date	Jul 30, 2018
Priority date	Jul 17, 2012
Publication date	Sep 15, 2020
Grant date	Sep 15, 2020

Abstract

Described is a mobile phase fitting having reduced corrosion and erosion. The fitting includes a coupling body, compression screw, compression member and gasket. The coupling body has a threaded bore at one end, a tapered cavity, a narrow bore and a fluid channel. The compression screw has an axial bore to receive a tube and a threaded outer surface in engagement with the threaded bore of the coupling body. The compression member is disposed in the tapered cavity and has an axial opening to pass the tube and a tapered surface to engage a surface of the tapered cavity. The gasket is disposed in the narrow bore and has one surface in contact with the first internal surface and has a parallel surface to receive an end face of the tube. Mobile phase flows along a path that includes the tube, an opening in the gasket and the fluid channel.

First claim

What is claimed is:

1. A mobile phase fitting, comprising:
a coupling body having a first threaded bore at a first end, a cavity, a narrow bore and a fluid channel, the cavity extending from an internal end of the first threaded bore, the narrow bore extending from an end of the cavity that is opposite to the first threaded bore to a first internal surface, the fluid channel extending from the first internal surface to a second internal surface;
a compression screw having an axial bore to receive a tube and a threaded outer surface in engagement with the first threaded bore of the coupling body; and
a gasket disposed in the narrow bore and having a pair of parallel surfaces, a circumference, a gasket diameter that is greater than an outer diameter of the tube, and a central opening having a diameter that is greater than an inner diameter of the tube, one of the parallel surfaces in contact with the first internal surface and the other parallel surface configured to receive an end face of the tube, wherein the central opening extends between the parallel surfaces and wherein the mobile phase flows along a path that includes the tube, the central opening in the gasket and the fluid channel of the coupling body such that the mobile phase does not contact the first internal surface.

2. The mobile phase fitting of claim 1 further comprising a compression member disposed within the cavity and having an axial opening to pass the tube and a surface to engage a surface of the cavity.

3. The mobile phase fitting of claim 2 wherein the cavity is a tapered cavity and the surface of the compression member is a tapered surface configured to engage the tapered cavity.

4. The mobile phase fitting of claim 2 wherein the compression member comprises at least one ferrule.

5. The mobile phase fitting of claim 1 wherein the coupling body has a second end opposite to the first end and wherein the coupling body has a second threaded bore extending from the second end to the second internal surface.

6. The mobile phase fitting of claim 5 wherein the second threaded bore is configured to engage a threaded surface of a chromatography system component.

7. The mobile phase fitting of claim 1 wherein the gasket comprises a polymer material.

8. The mobile phase fitting of claim 1 wherein the gasket comprises a polymer resistant to corrosion and erosion effects of supercritical fluid.

9. The mobile phase fitting of claim 1 wherein the narrow bore has a circumference and wherein the gasket is secured in place by an interference fit between the outer circumference and the circumference of the narrow bore.

Assignees

• Waters Technologies Corp

Inventors

• Belanger Jonathan L
• Cormier Sylvain
• Trudeau Steven D
• Keenan Paul
• Mccormick Daniel J

Classifications

• B01D15/40 Primary

  using supercritical fluid as mobile phase or eluent · CPC title

• B01D15/22

  relating to the construction of the column · CPC title

• G01N30/6004

  end pieces · CPC title

• G01N30/6026

  Fluid seals · CPC title

• B01D15/10

  characterised by constructional or operational features · CPC title