Modified Hydrocyanine Dyes for the Detection of Reactive Oxygen Species
US-2018202936-A1 · Jul 19, 2018 · US
US10774059B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10774059-B2 |
| Application number | US-201916446604-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 19, 2019 |
| Priority date | Dec 19, 2016 |
| Publication date | Sep 15, 2020 |
| Grant date | Sep 15, 2020 |
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The disclosures herein provide compounds of formula I or its pharmaceutical acceptable salts, as well as polymorphs, enantiomers, stereoisomers, solvates, and hydrates thereof. These compounds may be formulated as pharmaceutical compositions. The pharmaceutical compositions may be formulated for oral administration, intravenous, spray, parenteral, lozenge, solution, syrup, sachet, transdermal administration, or injection. Such compositions may be used to treatment of inflammation or its associated complications.
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The invention claimed is: 1. A compound selected from the group consisting of 2. A pharmaceutical composition comprising a compound of claim 1 and a pharmaceutically acceptable carrier. 3. The pharmaceutical composition of claim 2 , wherein said pharmaceutical composition is formulated to for oral administration, delayed release or sustained release, transmucosal administration, syrup, topical administration, parenteral administration, injection, subdermal administration, oral solution, rectal administration, buccal administration or transdermal administration. 4. The pharmaceutical composition of claim 3 , wherein said pharmaceutical composition is formulated for the treatment of inflammation, inflammatory pain and post-surgery inflammation.
polycyclic · CPC title
Polycarboxylic acid esters, the acid moiety containing more than two carboxyl groups · CPC title
Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] · CPC title
with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms · CPC title
Radicals substituted by doubly bound oxygen or sulfur atoms or by two such atoms singly bound to the same carbon atom · CPC title
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