Methods of treating cancer by targeting tumor-associated macrophages
US-2024415921-A1 · Dec 19, 2024 · US
US10772827B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10772827-B2 |
| Application number | US-201615775813-A |
| Country | US |
| Kind code | B2 |
| Filing date | Nov 14, 2016 |
| Priority date | Nov 13, 2015 |
| Publication date | Sep 15, 2020 |
| Grant date | Sep 15, 2020 |
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The present invention relates to a nasal administration composition for preventing or treating ischemic cerebrovascular disease, containing a Fas targeting peptide (FTP). When using the pharmaceutical composition or kit of the present invention, a drug can be effectively delivered to brain tissue and the ischemic cerebrovascular disease of a subject can be effectively prevented or treated.
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What is claimed is: 1. A method of treating an ischemic stroke, comprising intranasally administering a pharmaceutically effective amount of a pharmaceutical composition to a subject in need thereof, wherein the pharmaceutical composition comprises a linear FAS targeting peptide (FTP) having the amino acid sequence of SEQ ID NO: 1 and wherein the intranasal administration is performed while a subject is in a sleeping, anesthetized, or unconscious state. 2. The method of claim 1 , wherein the pharmaceutical composition is contained in an injection device comprising a container configured to contain the pharmaceutical composition to be intranasally administered.
Peptides having 5 to 11 amino acids {(A61K38/043 - A61K38/046 take precedence)} · CPC title
Medicinal preparations characterised by special physical form {(nuclear magnetic resonance contrast preparations or magnetic resonance imaging contrast preparations A61K49/18; preparations containing radioactive substances A61K51/12)} · CPC title
for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis · CPC title
Nose · CPC title
of the injector type · CPC title
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