Determining medical outcome quality

Patent metadata

Field	Value
Publication number	US-10769240-B2
Application number	US-201515311833-A
Country	US
Kind code	B2
Filing date	Apr 30, 2015
Priority date	May 16, 2014
Publication date	Sep 8, 2020
Grant date	Sep 8, 2020

Abstract

The present invention relates to a medical data processing method of determining an outcome quality of a medical procedure, the method comprising the following steps which are constituted to be executed by a computer: a) acquiring (S1) pre-completion medical image data describing an anatomical structure of a patient's body in a state before the medical procedure has been completed on the anatomical structure, the anatomical structure being subject to the medical procedure; b) acquiring (S1) pre-completion non-image medical data describing a state and medical history of the patient before the medical procedure has been completed on the anatomical structure; c) acquiring (S2) medical procedure planning data describing a plan for execution of the medical procedure to be carried out on the anatomical structure; d) determining (S2), based on the pre-completion medical image data and the medical procedure planning data, procedure application describing an application of the medical procedure planning data to the pre-completion medical image data; e) acquiring (S5) post-completion non-image medical data describing a state and medical history of the patient after the medical procedure has been completed on the anatomical structure; f) acquiring (S5) post-completion medical image data describing the anatomical structure in a state after the medical procedure has been completed on the anatomical structure; g) determining (S6, S7), based on the procedure application data and the pre-completion non-image medical data and the post-completion non-image medical data and the post-completion medical image data, outcome quality data comprising a quality measure describing a quality of the outcome of the medical procedure, the quality measure for example being specific to the indication in question, properties of the patient and the executive medical entity.

First claim

The invention claimed is:

1. A computer implemented image processing method for the assessment of medical procedures, comprising:
acquiring pre-completion medical image data describing an anatomical structure of a patient's body in a state before the medical procedure has been completed on the anatomical structure, the anatomical structure being subject to the medical procedure;
the medical procedure being at least one of radiotherapy or radiosurgery procedure;
acquiring pre-completion non-image medical data describing a state and medical history of the patient before the medical procedure has been completed on the anatomical structure;
acquiring medical procedure planning data describing a plan for execution of the medical procedure to be carried out on the anatomical structure;
determining, based on the pre-completion medical image data and the medical procedure planning data, procedure application data describing an application of the medical procedure planning data to the pre-completion medical image data, wherein determining the procedure application data comprises establishing a coordinate mapping between the medical procedure planning data and the pre-completion medical image data;
acquiring atlas data describing an image-based model of the anatomical structure as a common reference frame, wherein the atlas data is multi-modal;
linking available medical image data, including the pre-completion medical image data and the procedure application data, across a plurality of patients to the common reference frame by applying an image fusion algorithm;
establishing, by the image fusion algorithm, a transformation between a common reference frame of the atlas data and the pre-completion medical image data and the procedure application data by applying the image fusion to the atlas data, pre-completion medical image data and the procedure application data;
wherein the transformation provides a measure of similarity between the atlas data and the pre-completion medical image data and the procedure application data by comparing the distribution of color values in each of the atlas data, pre-completion medical image data and procedure application data;
creating a visual representation of a dose distribution for the radiotherapy or radiosurgery generated as an overlay on the anatomical structure to at least partially generate the procedure planning data;
applying at least the procedure application data to the radiosurgery or radiotherapy procedure;
acquiring post-completion non-image medical data describing a state and medical history of the patient after the medical procedure has been completed on the anatomical structure;
acquiring post-completion medical image data describing the anatomical structure in a state after the medical procedure has been completed on the anatomical structure;
applying the transformation to the post-completion medical image data;
determining, based on the procedure application data and the pre-completion non-image medical data and the post-completion non-image medical data and the post-completion medical image data, outcome quality data comprising a quality measure describing a quality of the outcome of the medical procedure, wherein the quality measure describes a measure of accuracy of execution of the medical procedure, wherein the measure of accuracy is described by a value defining a geometric difference between the procedure application data and the post-completion medical image data;
modifying the procedure planning data based upon the outcome quality data.

2. A computer implemented image processing method for determining an outcome quality of a medical procedure, comprising:
acquiring pre-completion medical image data describing an anatomical structure of a patient's body in a state before the medical procedure has been completed on the anatomical structure, the anatomical structure being subject to the medical procedure;
the medical procedure being at least one of radiotherapy or radiosurgery procedure;
acquiring pre-completion non-image medical data describing a state and medical history of the patient before the medical procedure has been completed on the anatomical structure;
acquiring medical procedure planning data describing a plan for execution of the medical procedure to be carried out on the anatomical structure;
determining, based on the pre-completion medical image data and the medical procedure planning data, procedure application data describing an application of the medical procedure planning data to the pre-completion medical image data, wherein determining the procedure application data comprises establishing a coordinate mapping between the medical procedure planning data and the pre-completion medical image data;
establishing, by an image fusion algorithm, a transformation between a common reference frame of atlas data and the pre-completion medical image data and the procedure application data by applying the image fusion to the atlas data, pre-completion medical image data and the procedure application data;
wherein the transformation provides a measure of similarity between the atlas data and the pre-completion medical image data and the procedure application data by comparing the distribution of color values in each of the atlas data, pre-completion medical image data and procedure application data;
creating a visual representation of a dose distribution for the radiotherapy or radiosurgery generated as an overlay on the anatomical structure to at least partially generate the procedure planning data;
acquiring post-completion non-image medical data describing a state and medical history of the patient after the medical procedure has been completed on the anatomical structure;
acquiring post-completion medical image data describing the anatomical structure in a state after the medical procedure has been completed on the anatomical structure;
applying the transformation to the post-completion medical image data;
determining, based on the procedure application data and the pre-completion non-image medical data and the post-completion non-image medical data and the post-completion medical image data, outcome quality data comprising a quality measure describing a quality of the outcome of the medical procedure;
wherein the quality measure describes a measure of accuracy of execution of the medical procedure;
wherein the measure of accuracy is described by a value defining a geometric difference between the procedure application data and the post-completion medical image data.

3. The method according to claim 2 , wherein the measure of the accuracy is described by a statistical metric derived from the comparison of the pre-completion medical image data and the post-completion medical image data in regard of the of at least one of the pre-completion non-image medical data and the post-completion non-image medical data.

4. The method according to claim 2 , wherein the outcome quality data is determined by comparing at least one of a geometry, in particular at least one of a size, in particular volume, and shape, and metabolic activity, of tumour tissue described by the procedure application data and the post-treatment medical image data.

5. The method according to claim 2 , wherein the outcome quality data is determined by determining a deviation, in particular a deviation of at least one of an implantation trajectory, location or field of effect and a cavity between the procedure application data and the post-completion medical image data.

6. The method according to claim 2 , wherein the method is executed for a plurality of patients and a quality measure is determined for each one of the patients, and wherein statistical quality data is determined based on the outcome quality data determined for each patient of the plurality

Assignees

• Brainlab Ag

Inventors

• Vilsmeier Stefan
• Varkuti Bálint

Classifications

• G16H50/70 Primary

  for mining of medical data, e.g. analysing previous cases of other patients · CPC title

• G16H30/40

  for processing medical images, e.g. editing · CPC title

• G16H40/20

  for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms · CPC title

• G16H40/63

  for local operation · CPC title

• G16H20/40

  relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture · CPC title