Systems and methods for tagging and acoustically characterizing containers

Patent metadata

Field	Value
Publication number	US-10766027-B2
Application number	US-201615289692-A
Country	US
Kind code	B2
Filing date	Oct 10, 2016
Priority date	Oct 12, 2015
Publication date	Sep 8, 2020
Grant date	Sep 8, 2020

Abstract

Embodiments of the present invention provide systems and methods for tagging and acoustically characterizing containers.

First claim

What is claimed is:

1. A container configured to hold a fluid, the container comprising:
at least one vertical sidewall; and
a bottom coupled to the at least one vertical sidewall, the bottom including a plurality of recesses, grooves, or protrusions thereon or therein so as to provide a plurality of times of flight of an acoustic signal through the bottom;
wherein the plurality of recesses, grooves, or protrusions include a hydrophobic region configured so as to increase or decrease an amplitude of a reflection of the acoustic signal.

2. The container of claim 1 , wherein the plurality of recesses, grooves, or protrusions include a hydrophobic micropillar array.

3. The container of claim 1 , wherein the plurality of recesses, grooves, or protrusions are configured so as to be located outside of an acoustic path between the fluid and an acoustic transducer generating the acoustic signal.

4. The container of claim 1 , wherein the plurality of recesses, grooves, or protrusions are configured so as to be located along and within an acoustic path between the fluid and an acoustic transducer generating the acoustic signal.

5. The container of claim 1 , wherein the container includes a multiwell plate, a vertical sidewall of the at least one vertical sidewall and the bottom corresponding to a well of the multiwell plate.

6. The container of claim 1 , wherein the sidewall and the bottom include a plastic.

7. The container of claim 6 , wherein the plastic is selected from a group consisting of cyclic olefin polymer, cyclic olefin copolymer, polypropylene, and polystyrene.

8. A method of characterizing a container configured to hold a fluid, the method comprising:
providing the container, the container comprising:
at least one vertical sidewall; and
a bottom coupled to the at least one vertical sidewall, the bottom including a plurality of recesses, grooves, or protrusions thereon or therein;

transmitting an acoustic signal through the bottom, the plurality of recesses, grooves, or protrusions providing a plurality of times of flight of the acoustic signal through the bottom;
receiving a reflection of the transmitted acoustic signal; and
characterizing an acoustic impedance of the container based on the reflection;
wherein the plurality of recesses, grooves, or protrusions include a hydrophobic region configured so as to increase the reflection of the transmitted acoustic signal.

9. The method of claim 8 , wherein the plurality of recesses, grooves, or protrusions include a hydrophobic micropillar array.

10. The method of claim 8 , wherein the plurality of recesses, grooves, or protrusions are located outside of an acoustic path between the fluid and an acoustic transducer generating the acoustic signal.

11. The method of claim 8 , wherein the plurality of recesses, grooves, or protrusions are located along and within an acoustic path between the fluid and an acoustic transducer generating the acoustic signal.

12. The method of claim 8 , wherein the container includes a multiwell plate, and a vertical sidewall of the at least one vertical sidewall and the bottom correspond to a well of the multiwell plate.

13. The method of claim 8 , wherein the sidewall and the bottom include a plastic.

14. The method of claim 13 , wherein the plastic is selected from a group consisting, of cyclic olefin polymer, cyclic olefin copolymer, polypropylene, and polystyrene.

15. A system for characterizing a container configured to hold a fluid, the system comprising:
the container, the container comprising:
at least one vertical sidewall; and
a bottom coupled to the at least one vertical sidewall, the bottom including a plurality of recesses, grooves, or protrusions thereon or therein;

an acoustic transducer configured so as to transmit an acoustic signal through the bottom, the plurality of recesses, grooves, or protrusions providing a plurality of times of flight of the acoustic signal through the bottom, the acoustic transducer being further configured so as to receive a reflection of the transmitted acoustic signal; and
a controller configured so as to characterize an acoustic impedance of the container based on the reflection;
wherein the plurality of recesses, grooves, or protrusions include a hydrophobic region configured so as to increase the reflection of the transmitted acoustic signal.

16. The system of claim 15 , wherein the plurality of recesses, grooves, or protrusions include a hydrophobic micropillar array.

17. The system of claim 15 , wherein the plurality of recesses, grooves, or protrusions are located outside of an acoustic path between the fluid and an acoustic transducer generating the acoustic signal.

18. The system of claim 15 , wherein the plurality of recesses, grooves, or protrusions are located along and within an acoustic path between the fluid and an acoustic transducer generating the acoustic signal.

19. The system of claim 15 , wherein the container includes a multiwell plate, a vertical sidewall of the at least one vertical sidewall and the bottom corresponding to a well of the multiwell plate.

20. The system of claim 15 , wherein the sidewall and the bottom include a plastic.

21. The system of claim 20 , wherein the plastic is selected from a group consisting of cyclic olefin polymer, cyclic olefin copolymer, polypropylene, and polystyrene.

Assignees

• Labcyte Inc

Inventors

• Sackmann Eric
• DATWANI Sammy
• HINKSON Stephen

Classifications

• G01N2291/2695

  Bottles, containers · CPC title

• G01N29/09 Primary

  by measuring mechanical or acoustic impedance · CPC title

• B05B17/06

  using ultrasonic {or other kinds of} vibrations · CPC title

• B01L2400/0439

  ultrasonic vibrations, vibrating piezo elements · CPC title

• B01L2300/0851

  Bottom walls · CPC title