Method for extracting 1,5-pentanediamine from solution system containing 1,5-pentanediamine salt

Patent metadata

Field	Value
Publication number	US-10759737-B2
Application number	US-201616075929-A
Country	US
Kind code	B2
Filing date	Sep 7, 2016
Priority date	Feb 6, 2016
Publication date	Sep 1, 2020
Grant date	Sep 1, 2020

Abstract

Provided is a method for extracting a 1,5-pentanediamine from a solution system containing a 1,5-pentanediamine salt. The method comprises adding to the solution system an insoluble basic substance to form a solution system containing free 1,5-pentanediamine. The provided method has high applicability, is easy to use, and is environmentally-friendly, significantly lowering raw material costs and operating costs for the entire manufacturing process. The method achieves a high recovery rate for pentanediamine, and is more suitable for industrial-scale production.

First claim

What is claimed is:

1. A method for extracting 1, 5-pentanediamine from a solution system containing a 1,5-pentanediamine salt, comprising:
(i) adding to the solution system a basic substance to form a resulting solution system containing free 1,5-pentanediamine, the 1,5-pentanediamine salt being selected from a group consisting of sulfate, carbonate, phosphate, hydrochloride, and dicarboxylate of 1,5-pentanediamine, and the basic substance being selected from a group consisting of solid magnesium hydroxide, calcium oxide, and magnesium oxide; and
(ii) directly subjecting the resulting solution system containing free 1,5-pentanediamine to distillation/evaporation to obtain a solution of 1,5-pentanediamine, without separating solid substances from the resulting solution system or adding organic solvent prior to distillation/evaporation.

2. The method according to claim 1 , wherein the molar amount of sulfate, carbonate, and phosphate of 1,5-pentanediamine in the solution system is not less than 70% of the total molar amount of the 1,5-pentanediamine salt in the solution system.

3. The method according to claim 1 , wherein the solution system containing the 1,5-pentanediamine salt is an aqueous solution containing the 1,5-pentanediamine salt, an enzyme converting solution of 1,5-pentanediamine or a fermentation broth of 1,5-pentanediamine.

4. The method according to claim 2 , wherein the solution system containing the 1,5-pentanediamine salt is an aqueous solution containing the 1,5-pentanediamine salt, an enzyme converting solution of 1,5-pentanediamine or a fermentation broth of 1,5-pentanediamine.

5. The method according to claim 1 , wherein the basic substance is added at a temperature from 60° C. to 95° C.

6. The method according to claim 2 , wherein the basic substance is added at a temperature from 60° C. to 95° C.

7. The method according to claim 1 , further comprising concentrating the resulting solution system containing free 1,5-pentanediamine prior to distillation/evaporation.

8. The method according to claim 1 , wherein the step of distillation/evaporation is performed at a temperature from 40 to 250° C.

9. The method according to claim 1 , wherein the step of distillation/evaporation is performed at a pressure not higher than −0.05 Mpa, the pressure value being a gauge pressure value.

10. The method according to claim 1 , further comprising subjecting the solution system to a pretreatment process prior to adding the basic substance, wherein the pretreatment process is selected from the group consisting of a sterilization process, a decolorization process, a concentration process, and a combination thereof.

11. The method according to claim 1 , wherein the molar amount of sulfate, carbonate, and phosphate of 1, 5-pentanediamine in the solution system is not less than 75% of the total molar amount of the 1,5-pentanediamine salt in the solution system.

12. The method according to claim 1 , wherein the molar amount of sulfate, carbonate, and phosphate of 1, 5-pentanediamine in the solution system is not less than 80% of the total molar amount of the 1,5-pentanediamine salt in the solution system.

13. The method according to claim 1 , wherein the molar amount of sulfate, carbonate, and phosphate of 1, 5-pentanediamine in the solution system is not less than 85% of the total molar amount of the 1,5-pentanediamine salt in the solution system.

Assignees

• Cathay Biotech Inc
• Cibt America Inc

Inventors

• Liu Xiucai
• Qin Bingbing
• Yang Chen

Classifications

• C12P13/001 Primary

  Amines; Imines · CPC title

• C12P13/00

  Preparation of nitrogen-containing organic compounds · CPC title

• C07C211/09

  Diamines · CPC title

• C07C209/84 Primary

  Purification · CPC title

• C07C209/86 Primary

  Separation · CPC title