Spectral imaging phantom and method

Patent metadata

Field	Value
Publication number	US-10758202-B2
Application number	US-201615758367-A
Country	US
Kind code	B2
Filing date	Sep 22, 2016
Priority date	Sep 23, 2015
Publication date	Sep 1, 2020
Grant date	Sep 1, 2020

Abstract

The present invention is directed towards spectral imaging, wherein a dedicated spectral imaging phantom is scanned with a spectral x-ray device to obtain spectral imaging data of the spectral imaging phantom. Said imaging data of the spectral imaging phantom is used as input for obtaining improved further imaging data of a subject of which a spectral scan is performed subsequent to or simultaneous with the spectral scan of the spectral imaging phantom. Improved further imaging data may be obtained by using the spectral phantom imaging data as input for imaging data correction, for providing a recommendation and/or for further data processing.

First claim

The invention claimed is:

1. A spectral imaging phantom for a spectral x-ray imaging device, the spectral imaging phantom comprising a phantom body that comprises:
a bulk of low attenuation material;
a first insert positioned in the bulk, the first insert comprising a material comprising or corresponding to a material with a first Compton scatter and a first photo-electric absorption with respect to a scan energy of the spectral x-ray imaging device; and
a second insert positioned in the bulk, the second insert comprising a material comprising or corresponding to a material with a second Compton scatter and a second photo-electric absorption with respect to the scan energy,
wherein the first insert and the second insert have substantially the same attenuation profile with respect to the scan energy, and
wherein a ratio of the first photo-electric absorption and the first Compton scatter is selected to be different from a ratio of the second photo-electric absorption and the second Compton scatter.

2. The spectral imaging phantom according to claim 1 , comprising at least one further insert comprising a material comprising or corresponding to a contrast agent at a first concentration, a further contrast agent at a first and/or a further concentration and/or a further material with a further Compton scatter and a further photo-electric absorption, comprising combinations thereof.

3. The spectral imaging phantom according to claim 2 , wherein the at least one further insert comprise iodine or gadolinium contrast agents in one or more different concentrations and/or Teflon, PMMA, Polycarbonate, Polyethylene, Sodium Hydrogen Phosphate or Potassium Hydrogen Phosphate.

4. The spectral imaging phantom according to claim 2 , wherein the first insert is chosen such that it mimics attenuation characteristics of a part of a subject to be imaged; and for the spectral imaging phantom, wherein the at least one further insert is chosen such that it mimics attenuation characteristics of a part of the subject to be imaged.

5. The spectral imaging phantom according to claim 1 , wherein the first insert comprises a material comprising or corresponding to iodine or gadolinium contrast agents in one or more different concentrations or Teflon, PMMA, Polycarbonate, Polyethylene, Sodium Hydrogen Phosphate or Potassium Hydrogen Phosphate.

6. The spectral imaging phantom according to claim 1 , wherein the phantom body has flat shape or an arched shape, such that it can be placed under, on or over a subject to be scanned.

7. The spectral imaging phantom according to claim 1 , wherein the phantom body has an elongated shape.

8. The spectral imaging phantom according to claim 1 , wherein the phantom body and inserts are solid.

9. The spectral imaging phantom according to claim 1 , wherein the inserts are permanently fixed in the phantom body.

10. A spectral imaging system comprising:
a spectral x-ray imaging device; and
a spectral imaging phantom,
wherein the spectral imaging phantom comprising a phantom body that comprises:
a bulk of low attenuation material; a first insert positioned in the bulk, the first insert comprising a material comprising or corresponding to a material with a first Compton scatter and a first photo-electric absorption with respect to a scan energy of the spectral x-ray imaging device; and
a second insert positioned in the bulk, the second insert comprising a material comprising or corresponding to a material with a second Compton scatter and a second photo-electric absorption with respect to the scan energy, wherein the first insert and the second insert have substantially the same attenuation profile with respect to the scan energy, and wherein a ratio of the first photo-electric absorption and the first Compton scatter is selected to be different from a ratio of the second photo-electric absorption and the second Compton scatter.

11. The spectral imaging system according to claim 10 , wherein the spectral imaging phantom is embedded in a subject support of the spectral x-ray imaging device.

12. The spectral imaging system according to claim 10 , wherein the x-ray imaging device is a spectral computed tomography imaging device.

13. A spectral imaging method comprising:
inserting a spectral imaging phantom in an examination region of a spectral x-ray imaging device;
performing a spectral x-ray scan comprising at last a scan of the spectral imaging phantom, thereby obtaining spectral imaging data of at least the spectral computed tomography phantom;
using the obtained imaging data of the spectral computed tomography phantom as input for obtaining improved further imaging data of a subject of which a spectral computed tomography scan is performed subsequent to or simultaneous with the spectral computed tomography scan of the spectral imaging phantom;
wherein the spectral imaging phantom comprising a phantom body that comprises: a bulk of low attenuation material; a first insert positioned in the bulk, the first insert comprising a material comprising or corresponding to a material with a first Compton scatter and a first photo-electric absorption with respect to a scan energy of the spectral x-ray imaging device; and a second insert positioned in the bulk, the second insert comprising a material comprising or corresponding to a material with a second Compton scatter and a second photo-electric absorption with respect to the scan energy, wherein the first insert and the second insert have substantially the same attenuation profile with respect to the scan energy, and wherein a ratio of the first photo-electric absorption and the first Compton scatter is selected to be different from a ratio of the second photo-electric absorption and the second Compton scatter.

14. The spectral imaging method according to claim 13 , wherein the spectral imaging phantom is used as input for obtaining improved image data by using it as input for imaging data correction, for providing a recommendation and/or for further data processing.

15. The spectral imaging method according to claim 14 , wherein the spectral scan of the subject is performed simultaneously with the spectral scan of the spectral phantom.

16. The spectral imaging method according to claim 13 , wherein the subject is a patient and further imaging data is obtained of at least an area of interest in or on the patient.

17. The spectral imaging method according to claim 13 , further comprising:
quantifying a crosstalk in material decomposition of the imaging data by application of a heuristic linear model to the image data, a set of free parameters of the heuristic linear model being optimized for a cost function;
correcting the obtained image data for the quantified crosstalk with the optimized free parameters; and, optionally,
determining at least one system parameter and use said at least one system parameter in the correction of the quantified crosstalk.

18. The spectral imaging method according to claim 13 , further comprising:
comparing the obtained imaging data of the spectral phantom with reference imaging data, said reference data comprising theoretical data, data measured with other sources, previously measured data of a subject to be imaged, and/or data of the spectral phantom obtained during a previous scan of the spectral phantom, preferably a previous scan shortly after a latest calibration procedure; and
providing a recommendation for a special action, for instance a recommendation for performing a new calibration when a difference between the obtained imaging data and the imaging data obtained

Assignees

• Koninklijke Philips Nv

Inventors

• Daerr Heiner
• Koehler Thomas

Classifications

• A61B6/032 Primary

  Transmission computed tomography [CT] · CPC title

• G09B23/286

  for scanning or photography techniques, e.g. X-rays, ultrasonics · CPC title

• G09B23/30

  Anatomical models {(G09B23/281 - G09B23/288 take precedence)} · CPC title

• A61B6/583 Primary

  using calibration phantoms · CPC title