Vaccine compositions of herpesvirus envelope protein combinations to induce immune response
US-2019367561-A1 · Dec 5, 2019 · US
ORF7 deficient varicella virus, vaccine comprising the virus and use thereof
US10752885B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10752885-B2 |
| Application number | US-201815865540-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jan 9, 2018 |
| Priority date | Jul 28, 2009 |
| Publication date | Aug 25, 2020 |
| Grant date | Aug 25, 2020 |
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Abstract
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Provided are an ORF7 deficient varicella virus, an vaccine comprising the virus and use thereof, as well as a method for the production the virus.
First claim
Opening claim text (preview).
What is claimed is: 1. A vaccine against varicella and/or herpes zoster, comprising a varicella virus, and an excipient or carrier acceptable in vaccines, wherein the ORF7 of said varicella virus is replaced by SEQ ID NO:13 so that the resulting virus is unable to infect human skin or sensory ganglion. 2. The vaccine according to claim 1 , wherein the varicella virus is the varicella virus deposited in China General Microbiological Culture Collection Center, Institute of Microbiology Chinese Academy of Sciences, NO. 1 West Beichen Road, Chaoyang District, Beijing 100101, China on Jul. 28, 2009 with deposit number CGMCC No. 3207. 3. A method of inducing an immune response against varicella and/or herpes zoster, comprising administering a prophylactic effective amount of the vaccine according to claim 1 . 4. An immunogenic composition comprising a prophylactic effective amount of the vaccine according to claim 1 .
Assignees
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Classifications
- A61K39/25Primary
Varicella-zoster virus · CPC title
New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes · CPC title
from viruses · CPC title
Viral vectors · CPC title
- C12N7/00Primary
Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof (preparing medicinal viral antigen or antibody compositions, e.g. virus vaccines, A61K39/00) · CPC title
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Frequently asked questions
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- What does patent US10752885B2 cover?
- Provided are an ORF7 deficient varicella virus, an vaccine comprising the virus and use thereof, as well as a method for the production the virus.
- Who is the assignee on this patent?
- Beijing Wantai Biological Pharmacy Entpr Co Ltd, Univ Rutgers, Univ Xiamen
- What technology area does this patent fall under?
- Primary CPC classification A61K39/25. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Aug 25 2020 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).