Blood purification apparatus

Patent metadata

Field	Value
Publication number	US-10751459-B2
Application number	US-201715788040-A
Country	US
Kind code	B2
Filing date	Oct 19, 2017
Priority date	Apr 20, 2015
Publication date	Aug 25, 2020
Grant date	Aug 25, 2020

Abstract

A blood purification apparatus employing a single-needle double-pump method and being capable of automatically discharging a priming solution that has undergone substitution from a blood circuit during blood removal. A blood purification apparatus includes a blood circuit to which an only puncture needle is connectable, a dialyzer that purifies blood flowing in the blood circuit, a first blood pump, a second blood pump, and a control device that allows the blood of a patient to be extracorporeally circulated through the blood circuit by causing the first blood pump and the second blood pump to alternately undergo normal rotation. During blood removal, the control device operates to substitute a priming solution in the blood circuit with the blood of the patient and to discharge the priming solution having undergone the substitution from the blood circuit by causing the first blood pump to undergo normal rotation and the second blood pump to undergo reverse rotation.

First claim

The invention claimed is:

1. A blood purification apparatus that performs blood purification treatment while extracorporeally circulating blood of a patient by using an only puncture needle, the apparatus comprising:
a blood circuit including an arterial blood circuit and a venous blood circuit to respective distal ends of which the only puncture needle is connectable, the blood circuit allowing the blood of the patient to be extracorporeally circulated from the distal end of the arterial blood circuit to the distal end of the venous blood circuit;
a blood purification device provided between the arterial blood circuit and the venous blood circuit and that purifies the blood of the patient flowing in the blood circuit;
a first blood pump that is a peristaltic pump provided to the arterial blood circuit and is capable of introducing the blood of the patient into the blood circuit through the puncture needle when activated to undergo normal rotation;
a second blood pump that is a peristaltic pump provided to the venous blood circuit and is capable of returning the blood in the blood circuit to the patient through the puncture needle when activated to undergo normal rotation; and
a control device that allows the blood of the patient to be extracorporeally circulated through the blood circuit by causing the first blood pump and the second blood pump to alternately undergo normal rotation,
wherein, during blood removal, the control device operates to substitute a priming solution in the blood circuit with the blood of the patient and the first blood pump undergoes normal rotation and the second blood pump undergoes reverse rotation to discharge the priming solution having undergone the substitution from the blood circuit.

2. The blood purification apparatus according to claim 1 , wherein, when the blood removal is performed, the control device activates the first blood pump and the second blood pump simultaneously.

3. The blood purification apparatus according to claim 1 , wherein a number of revolutions and a speed of rotation of each of the first blood pump and the second blood pump during the blood removal are set in accordance with a capacity of a portion between a site where the priming solution substituted with the blood is discharged and a site where a corresponding one of the first blood pump and the second blood pump is provided.

4. The blood purification apparatus according to claim 1 , wherein the blood purification device includes blood purification membranes that purify the blood and define blood flow routes in which the blood of the patient flows and dialysate flow routes in which a dialysate flows, and wherein, during the blood removal, the control device causes the priming solution substituted with the blood to be discharged after being filtered from the blood flow routes into the dialysate flow routes.

5. The blood purification apparatus according to claim 4 , further comprising a pressure detection device capable of detecting a pressure generated when the priming solution substituted with the blood is discharged while being filtered from the blood flow routes into the dialysate flow routes, wherein, during the blood removal, the control device controls the first blood pump and the second blood pump on basis of the pressure detected by the pressure detection device.

6. The blood purification apparatus according to claim 1 , wherein the blood circuit includes an overflow line provided between the first blood pump and the second blood pump, and wherein, during the blood removal, the control device allows the priming solution substituted with the blood to be discharged through the overflow line.

7. The blood purification apparatus according to claim 4 , further comprising an ultrafiltration pump for removing water from the blood that is extracorporeally circulated through the blood circuit, wherein, during the blood removal, the control device allows the priming solution substituted with the blood to be discharged by activating the ultrafiltration pump.

8. The blood purification apparatus according to claim 1 , wherein the arterial blood circuit includes an air-bubble detection device.

9. The blood purification apparatus according to claim 8 , wherein the arterial blood circuit includes an air-trap chamber upstream of the air-bubble detection device.

10. The blood purification apparatus according to claim 9 , wherein the blood enters through the only puncture needle into the air-trap chamber of the arterial blood circuit before flowing into a dialyzer when the first blood pump rotates under normal rotation and the second blood pump is off.

11. The blood purification apparatus according to claim 1 , wherein the venous blood circuit includes an air-bubble detection device.

12. The blood purification apparatus according to claim 11 , wherein the venous blood circuit includes an air-trap chamber downstream of the air-bubble detection device.

13. The blood purification apparatus according to claim 12 , wherein the blood passes through the air-trap chamber, then the air-bubble detection device, before passing through the only puncture needle when the second blood pump is operation in the normal rotation and the first blood pump stopped.

14. The blood purification apparatus according to claim 1 , wherein the blood purification apparatus includes an overflow line that extends from a blood circuit to a dialysate flow route.

15. The blood purification apparatus according to claim 14 , wherein the overflow line extends from a dialyzer-inlet-pressure chamber in the blood circuit to a dialysate drain line in the dialysate flow route.

16. The blood purification apparatus according to claim 15 , wherein the overflow line includes an overflow clamp that opens and closes the overflow line.

17. The blood purification apparatus according to claim 1 , wherein the blood circuit includes a wye with flexible tubes and the flexible tubes include a luer taper and screw that are connectable to a distal end of each of the arterial blood circuit and the venous blood circuit.

Assignees

• Nikkiso Co Ltd

Inventors

• Hasegawa Shinya
• Furuhashi Tomohiro
• Takeuchi Satoshi

Classifications

• A61M1/30 Primary

  Single needle dialysis {; Reciprocating systems, alternately withdrawing blood from and returning it to the patient, e.g. single-lumen-needle dialysis or single needle systems for hemofiltration or pheresis} · CPC title

• A61M2205/3341

  stabilising pressure or flow to avoid excessive variation · CPC title

• A61M2205/18

  with alarm · CPC title

• A61M2205/3365

  Rotational speed · CPC title

• A61M1/3638

  with a vapour trap · CPC title