Embolic devices and methods of manufacturing same

Patent metadata

Field	Value
Publication number	US-10743883-B2
Application number	US-201615393037-A
Country	US
Kind code	B2
Filing date	Dec 28, 2016
Priority date	Dec 30, 2015
Publication date	Aug 18, 2020
Grant date	Aug 18, 2020

Abstract

A flat embolic braid having a first side comprising a first side surface, and a second side comprising a second side surface facing in an opposite direction than the first side surface, the braid having an elongated constrained configuration for being deployed through a delivery catheter, and a three-dimensional unconstrained configuration, wherein in the three-dimensional unconstrained configuration, the braid assumes a plurality of successive loops in which the braid is at least partially twisted between successive loops of the plurality, so that the first side surface faces externally of each loop, and the second side surface faces an interior of each loop, respectively, regardless of a change in direction and/or orientation of the braid.

First claim

What is claimed is:

1. An embolic device, comprising:
an elongate flat member having a longitudinal axis, a first side comprising a first side surface, and a second side comprising a second side surface, the first and second sides being reverse to each other with the first side surface and second side surface facing in opposite directions,
the elongate flat member having an elongated constrained configuration for being deployed through a delivery catheter to targeted vascular site, and a three-dimensional unconstrained configuration,
wherein in the three-dimensional unconstrained configuration, the elongate flat member assumes a plurality of successive loops in which the elongate flat member is at least partially twisted about the longitudinal axis of the elongate flat member between each loop of the plurality, so that the first side surface faces externally of each loop, and the second side surface faces an interior of each loop, respectively, regardless of a change in direction and/or orientation of the elongate flat member, and wherein the directly adjacent loops to a first loop of the plurality of loops have respective rotational axes which are angled to the rotational axis of the first loop by 65-95 degrees.

2. The embolic device of claim 1 , wherein the elongate flat member comprises a braid formed out of one or more braid members.

3. The embolic device of claim 2 , wherein the elongate flat member comprises a flattened tubular braid.

4. The embolic device of claim 2 , wherein the elongate flat member comprises a single layer, flat ribbon braid.

5. The embolic device of claim 1 , wherein the three-dimensional unconstrained configuration is imparted on the elongate flat member by thermally treating the elongate flat member while the elongate flat member is wound in alternating directions about respective posts extending outwardly from a mandrel to thereby form the plurality of successive loops.

6. The embolic device of claim 1 , wherein the first loop is formed by winding the elongate flat member in a first direction and the adjacent loops are formed by winding the elongate flat member in an opposite direction to the first direction when viewed down an axis towards the centroid of the three-dimensional unconstrained configuration.

7. The embolic device of claim 1 , the plurality of successive loops comprising at least five successive loops.

8. The embolic device of claim 1 , wherein the elongate flat member in the three-dimensional unconstrained configuration comprises a twist pitch.

9. The embolic device of claim 8 , wherein the twist pitch is about 1.5 times 360°/πD, wherein D is an average curve diameter of adjacent loops.

10. The embolic device of claim 8 , wherein the twist pitch varies from approximately 0.25 to approximately 4 times (360°/πD).

11. The embolic device of claim 8 , wherein the twist pitch varies from approximately 0.75 to approximately 2.5 times (360°/πD).

12. The embolic device of claim 1 , wherein the elongate flat member that is at least partially twisted about the longitudinal axis of the elongate flat member between each loop of the plurality comprises a constant cross-section throughout the twists.

13. The embolic device of claim 1 , wherein the elongate flat member that is at least partially twisted about the longitudinal axis of the elongate flat member between each loop of the plurality comprises a variable cross-section throughout the twists.

14. The embolic device of claim 1 , wherein in the three-dimensional unconstrained configuration, the elongate flat member assumes a substantially spherical shape.

15. An embolic device for occluding an aneurysm, the embolic device comprising:
an elongate flat braid formed out of one or more metallic braid filaments or wires,
the elongate flat braid having a longitudinal axis, a first side comprising a first side surface, and a second side comprising a second side surface, the first and second sides being reverse to each other with the first side surface and second side surface facing in opposite directions,
the elongate flat braid having an elongated constrained configuration for being deployed through a delivery catheter into the aneurysm, and a three-dimensional unconstrained configuration after being deployed out of the delivery catheter within the aneurysm,
wherein in the three-dimensional unconstrained configuration, the elongate flat braid assumes a plurality of successive loops in which the elongate flat braid is at least partially twisted about the longitudinal axis of the elongate flat braid between each loop of the plurality, so that the first side surface faces externally of each loop towards an interior wall of the aneurysm, and the second side surface faces an interior of each loop, respectively, regardless of a change in direction and/or orientation of the elongate flat braid, wherein each loop defines a plane, and wherein the directly adjacent loops to a first loop of the plurality of loops have respective rotational axes which are angled to the rotational axis of the first loop by 65-95 degrees.

16. The embolic device of claim 15 , wherein the elongate flat braid comprises a flattened tubular braid.

17. The embolic device of claim 15 , wherein the elongate flat braid comprises a single layer, flat ribbon braid.

18. The embolic device of claim 15 , wherein the three-dimensional unconstrained configuration is imparted on the elongate flat braid by thermally treating the elongate flat braid while the elongate flat braid is wound in alternating directions about respective posts extending outwardly from a mandrel to thereby form the plurality of successive loops.

19. The embolic device of claim 15 , wherein the first loop is formed by winding the elongate flat member in a first direction and the adjacent loops are formed by winding the elongate flat member in an opposite direction to the first direction when viewed down an axis towards the centroid of the three-dimensional unconstrained configuration.

20. The embolic device of claim 15 , the plurality of successive loops comprising at least five successive loops.

21. An embolic device, comprising:
an elongate flat member having a longitudinal axis, a first side comprising a first side surface, and a second side comprising a second side surface, the first and second sides being reverse to each other with the first side surface and second side surface facing in opposite directions,
the elongate flat member having an elongated constrained configuration for being deployed through a delivery catheter to targeted vascular site, and a three-dimensional unconstrained configuration,
wherein in the three-dimensional unconstrained configuration, the elongate flat member assumes a plurality of successive loops in which the elongate flat member is at least partially twisted about the longitudinal axis of the elongate flat member between each loop of the plurality, so that the first side surface faces externally of each loop, and the second side surface faces an interior of each loop, respectively, regardless of a change in direction and/or orientation of the elongate flat member, and wherein the directly adjacent loops to a first loop of the plurality of loops have respective winding axes which are non-collinear and angled to a winding axis of the first loop and the first loop is formed by winding the elongate flat member in a first direction and the adjacent loops are formed by winding the elongate flat member in an opposite direction to the first direction when viewed down an axi

Assignees

• Stryker Corp
• Stryker European Holdings I Llc

Inventors

• Porter Stephen

Classifications

• B21F45/008

  of medical instruments, e.g. stents or corneal rings · CPC title

• A61F2/86

  Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure · CPC title

• A61B2017/1205

  Introduction devices · CPC title

• A61B2017/00867

  shape memory effect · CPC title

• A61B2017/00862

  elastic or resilient · CPC title