Ruthenium-diamine complexes and method for producing optically active compounds
US-9468919-B2 · Oct 18, 2016 · US
Compounds for treatment of angiogenesis-mediated diseases
US10738024B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10738024-B2 |
| Application number | US-201414888117-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 6, 2014 |
| Priority date | May 6, 2013 |
| Publication date | Aug 11, 2020 |
| Grant date | Aug 11, 2020 |
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- Title
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Abstract
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Synthetic cremastranone and cremastranone analogs are disclosed. Additionally, methods for synthesizing cremastranone and cremastranone analogs are disclosed. Methods of treating ocular neovascularization disorders and treating angiogenesis-mediated disease are also disclosed.
First claim
Opening claim text (preview).
What is claimed is: 1. A synthetic compound comprising formula (I) wherein R 1 is selected from the group consisting of hydroxyl and alkoxy, R 2 is selected from the group consisting of hydroxyl, alkoxy, substituted alkoxy, alkyl carbonyloxy, substituted alkyl carbonyloxy, alkyl carbonyl, substituted alkyl carbonyl, aryl carbonyloxy, substituted aryl carbonyloxy, halogen, amino, nitro, hydrocarbyl and substituted hydrocarbyl; R 3 is selected from the group consisting of hydroxyl and alkoxy; R 4 is independently selected from the group consisting of hydroxyl, alkoxy, substituted alkoxy, alkyl carbonyloxy, substituted alkyl carbonyloxy, alkyl carbonyl, substituted alkyl carbonyl, aryl carbonyloxy, substituted aryl carbonyloxy, halogen, amino, nitro, hydrocarbyl and substituted hydrocarbyl; R 5 is independently selected from the group consisting of hydrogen, alkoxy, substituted alkoxy, alkyl carbonyloxy, substituted alkyl carbonyloxy, alkyl carbonyl, aryl carbonyloxy, substituted aryl carbonyloxy, halogen, amino, nitro, hydrocrabyl and substituted hydrocarbyl; X is selected from the group consisting of CH, nitrogen, and Y, and Z are independently selected from the group consisting of CH 2 , nitrogen, and oxygen, wherein when R 1 is hydroxyl and R 2 is an alkoxy, R 3 is not hydroxy. 2. The synthetic compound selected from the group consisting of .
Assignees
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Classifications
a keto group being part of a condensed ring system with two or three rings, at least one ring being a six-membered aromatic ring · CPC title
condensed with one six-membered ring · CPC title
Ortho-condensed systems · CPC title
Oxygen atoms · CPC title
containing ether groups, [IMAGE cpc-sch-C07C-0958.gif] groups,[IMAGE cpc-sch-C07C-0959.gif] groups, or[IMAGE cpc-sch-C07C-0960.gif] groups · CPC title
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- What does patent US10738024B2 cover?
- Synthetic cremastranone and cremastranone analogs are disclosed. Additionally, methods for synthesizing cremastranone and cremastranone analogs are disclosed. Methods of treating ocular neovascularization disorders and treating angiogenesis-mediated disease are also disclosed.
- Who is the assignee on this patent?
- Univ Indiana Res & Tech Corp, Gachon Univ Of Industry-Academic Cooperation Foundation
- What technology area does this patent fall under?
- Primary CPC classification C07D311/22. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Aug 11 2020 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).