Transfilling device

Patent metadata

Field	Value
Publication number	US-10737026-B2
Application number	US-201615772171-A
Country	US
Kind code	B2
Filing date	Nov 8, 2016
Priority date	Nov 11, 2015
Publication date	Aug 11, 2020
Grant date	Aug 11, 2020

Abstract

Disclosed is a transfilling device ( 1 ) for transfilling a liquid drug from a cartridge ( 3 ) to a flexible reservoir ( 4 ). The transfilling device ( 1 ) includes a support unit ( 111 ) and a plunger ( 113 ), the support unit ( 111 ) configured to receive the cartridge ( 3 ), the plunger ( 113 ) being insertable into the cartridge ( 3 ), wherein the plunger ( 113 ) is displaceable relative to the support unit ( 111 ) along an advancement direction ( 2 ) between a plunger retracted position, where the plunger ( 113 ) is in a most distal position relative to the support unit ( 111 ), and a plunger advanced position, where the plunger ( 113 ) is in a most proximal position relative to the support unit ( 111 ), wherein the plunger ( 113 ) is configured to push a piston ( 32 ) of the cartridge ( 3 ) from a piston retracted position to a piston advanced position by displacing the plunger ( 113 ). The transfilling device ( 1 ) further includes a transfer cannula ( 12, 12 ′), wherein the transfer cannula ( 12, 12 ′) is configured to penetrate a flexible reservoir septum ( 41 ) with a cannula outlet end ( 122 ) and to penetrate a cartridge septum ( 31 ) with a cannula inlet end ( 121 ) and thereby to fluidly couple the flexible reservoir ( 4 ) with the cartridge ( 3 ). The transfilling device further includes a reservoir locking unit ( 13 ), wherein the reservoir locking unit ( ) is configured to releasably mechanically couple the support unit ( 111 ) to the flexible reservoir ( 4 ) and wherein the coupling of the reservoir locking unit ( 13 ) is designed such that the coupling is released in the plunger advanced position.

First claim

The invention claimed is:

1. Transfilling device for transfilling a liquid drug from a cartridge to a flexible reservoir, the transfilling device including:
a support unit and a plunger, the support unit configured to receive the cartridge, the plunger being insertable into the cartridge, wherein the plunger is displaceable relative to the support unit along an advancement direction between a plunger retracted position, where the plunger is in a most distal position relative to the support unit, and a plunger advanced position, where the plunger is in a most proximal position relative to the support unit, wherein the plunger is configured to push a piston of the cartridge from a piston retracted position to a piston advanced position by displacing the plunger;
a transfer cannula, wherein the transfer cannula is configured to penetrate a flexible reservoir septum with a cannula outlet end and to penetrate a cartridge septum with a cannula inlet end and thereby to fluidly couple the flexible reservoir with the cartridge;
a reservoir locking unit, wherein the reservoir locking unit has a coupling configured to releasably mechanically couple the support unit to the flexible reservoir when at least in the plunger retracted position and wherein the coupling of the reservoir locking unit is configured to release the support unit from the flexible reservoir in an automatic manner when in the plunger advanced position; and
a sliding unit engaged with the support unit in a sliding manner, wherein the sliding unit has the plunger; and
wherein the sliding unit is configured to engage the coupling of the reservoir locking unit to release the support unit from the flexible reservoir when in the plunger advanced position.

2. Transfilling device according to claim 1 , wherein the support unit is designed to receive a cylindrical cartridge having a filling volume between 1 and 4 ml.

3. Transfilling device according to claim 1 , wherein the plunger includes a motor coupler, configured to couple to a motor.

4. Transfilling device according to claim 1 , wherein the plunger is manually movable.

5. Transfilling device according to claim 1 , wherein the plunger is formed integral with the sliding unit.

6. Reservoir assembly including the flexible reservoir and the transfilling device according to claim 1 .

7. Reservoir assembly according to claim 6 , further including a rigid housing, wherein the flexible reservoir is mounted inside the rigid housing and the rigid housing including at least one port, the rigid housing made of plastic.

8. Reservoir assembly according to claim 7 , wherein the rigid housing includes the counter reservoir-locking unit, the counter reservoir-locking unit configured to engage with the reservoir locking unit.

9. Reservoir assembly according to claim 6 , wherein the reservoir assembly further includes a counter reservoir-locking unit, the counter reservoir-locking unit configured to engage with the reservoir locking unit.

10. Reservoir assembly according to claim 6 , wherein the flexible reservoir has a main extension plane, the main extension plane being substantially parallel to the advancement direction.

11. Reservoir assembly according to claim 6 , further including a dosing unit or an interface for mechanical and fluidic coupling to a dosing unit.

12. Infusion system including a dosing unit and the reservoir assembly according to claim 6 , wherein the reservoir assembly is fluidly coupled to the dosing unit.

13. Transfilling device for transfilling a liquid drug from a cartridge to a flexible reservoir, the transfilling device including:
a support unit and a plunger, the support unit configured to receive the cartridge, the plunger being insertable into the cartridge, wherein the plunger is displaceable relative to the support unit along an advancement direction between a plunger retracted position, where the plunger is in a most distal position relative to the support unit, and a plunger advanced position, where the plunger is in a most proximal position relative to the support unit, wherein the plunger is configured to push a piston of the cartridge from a piston retracted position to a piston advanced position by displacing the plunger;
a transfer cannula, wherein the transfer cannula is configured to penetrate a flexible reservoir septum with a cannula outlet end and to penetrate a cartridge septum with a cannula inlet end and thereby to fluidly couple the flexible reservoir with the cartridge;
a reservoir locking unit, wherein the reservoir locking unit is configured to releasably mechanically couple the support unit to the flexible reservoir and wherein the coupling of the reservoir locking unit is designed such that the coupling is released in the plunger advanced position; and
wherein the plunger and the support unit are configured to unreleas ably lock in the plunger advanced position.

14. Transfilling device according to claim 13 , wherein the plunger includes a motor coupler, configured to couple to a motor.

15. Transfilling device according to claim 13 , wherein the plunger is manually movable.

16. Transfilling device according to claim 13 , further including a sliding unit, wherein the plunger is formed integral with the sliding unit, the sliding unit being configured for sliding engagement with the support unit.

17. Reservoir assembly including the flexible reservoir and the transfilling device according to claim 13 .

18. Reservoir assembly according to claim 17 , further including a rigid housing, wherein the flexible reservoir is mounted inside the rigid housing and the rigid housing including at least one port, the rigid housing made of plastic.

19. Reservoir assembly according to claim 17 , wherein the reservoir assembly further includes a counter reservoir-locking unit, the counter reservoir-locking unit configured to engage with the reservoir locking unit.

20. Reservoir assembly according to claim 17 , further comprising a rigid housing, wherein the rigid housing includes a counter reservoir-locking unit, the counter reservoir-locking unit configured to engage with the reservoir locking unit.

21. Reservoir assembly according to claim 17 , wherein the flexible reservoir has a main extension plane, the main extension plane being substantially parallel to the advancement direction.

22. Reservoir assembly according to claim 17 , further including a dosing unit or an interface for mechanical and fluidic coupling to a dosing unit.

23. Infusion system including a dosing unit and the reservoir assembly according to claim 17 , wherein the reservoir assembly is fluidly coupled to the dosing unit.

24. Method for transfilling a liquid drug from a cartridge to a flexible reservoir the method including:
providing a transfilling device;
releasably coupling a support unit of the transfilling device to the flexible reservoir by a coupling of a reservoir locking unit;
receiving the cartridge in the support unit;
fluidly coupling the cartridge to the flexible reservoir by a transfer cannula, the transfer cannula penetrating a flexible reservoir septum with a cannula outlet end and penetrating a cartridge septum with a cannula inlet end;
displacing a plunger relative to the support unit along an advancement direction from a plunger retracted position, where the plunger is in a most distal position relative to the support unit to a plunger advanced position, where the plunger is in a most proximal position relative to the suppo

Assignees

• Roche Diabetes Care Inc

Inventors

• Teutsch David

Classifications

• A61M2005/2414

  from the side · CPC title

• A61M2005/14268

  with a reusable and a disposable component · CPC title

• B65B3/003

  Filling medical containers such as ampoules, vials, syringes or the like · CPC title

• A61M5/178

  Syringes · CPC title

• A61M2209/045

  for filling, e.g. for filling reservoirs · CPC title