Multichannel biphasic signal generator circuit

Patent metadata

Field	Value
Publication number	US-10729906-B2
Application number	US-201615383563-A
Country	US
Kind code	B2
Filing date	Dec 19, 2016
Priority date	Jun 18, 2014
Publication date	Aug 4, 2020
Grant date	Aug 4, 2020

Abstract

A circuit includes first and second current control sub-circuits connected in series between a DC supply voltage node and a reference voltage node and third and fourth current control sub-circuits connected in series between the DC supply voltage node and the reference voltage node. The circuit also includes a DC/DC converter with a first input terminal coupled to the first load node between the first and second current control sub-circuits, a second input terminal coupled to a second load node between the third and fourth current control sub-circuits, a first output terminal, and a second output terminal. The circuit further includes output electrodes, a routing sub-circuit for selectively coupling the output electrodes to the output terminals, and a controller configured for operating the routing sub-circuit and the current control sub-circuits to cause the DC/DC converter to supply biphasic pulses for at least one of the pairs of output electrodes.

First claim

What is claimed is:

1. A method for generating biphasic electrical stimulation pulses comprising:
providing an H-bridge circuit comprising first and second current control sub-circuits connected in series between a DC supply voltage node and a reference voltage node, third and fourth current control sub-circuits connected in series between the DC supply voltage node and the reference voltage node, and a transformer with a first input terminal coupled to a first load node between the first and the second current control sub-circuits and a second input terminal coupled to a second load node between the third and the fourth current control sub-circuits, wherein the first and the third current control sub-circuits comprise high-side current control circuits and wherein the second and the fourth current control sub-circuits comprise low-side current control circuits;
operating the first, the second, the third, the fourth current control sub-circuits to generate a biphasic pulse, the operating comprising:
closing the first and the fourth current control sub-circuits and opening the second and the third current control sub-circuits circuit to cause a current from the DC power supply voltage to be directed through the transformer in a first direction to generate a first portion of a biphasic pulse with a first polarity, and
closing the second and the third current control sub-circuits and opening the first and the fourth current control sub-circuits circuit to cause a current from the DC power supply voltage to be directed through the transformer in a second direction to generate a second portion of a biphasic pulse with a second polarity; and

selectively coupling output terminals of the transformer to one of a plurality of pairs of electrodes to deliver the first and the second portions of the biphasic pulse to the one of the plurality of electrode pairs.

2. The method of claim 1 , wherein the transformer comprises a non-center-tapped pulse transformer, wherein the first and the second input terminals are coupled to a primary winding of the transformer, wherein output terminals are coupled to a secondary winding of the transformer.

3. The method of claim 1 , wherein the first and the third current control sub-circuits are switching-type sub-circuits, and wherein the second and the fourth current control sub-circuits are variable current control sub-circuits, and wherein the operating comprises limiting an amount of current through the input terminals of the transformer.

4. The method of claim 3 , wherein the switching-type sub-circuits comprise MOSFETs, and wherein the variable current control sub-circuits comprise bipolar junction transistors.

5. The method of claim 4 , wherein the variable current control sub-circuits comprises sense resistors configured to sense the current through a primary winding of the transformer, and wherein the operating further comprising regulating the second and the fourth current control sub-circuits to control the voltage across each respective sense resistor.

6. The method of claim 3 , wherein at least one of the first and the third current control sub-circuits are configured to allow multiple amounts of current and at least one of the second and the fourth current control sub-circuits are configured to allow multiple amounts of current, and wherein the operating further comprises selecting the amount of current to control an amplitude for the first and the second portions of the biphasic pulse.

7. The method of claim 1 , wherein the at least one pair of stimulation electrodes comprises multiple pairs of electrodes, and wherein the output terminals of the transformer are sequentially coupled to each pair of electrodes so that the output terminals of the transformer are coupled to a single one of the pair of electrodes at a time.

8. The method of claim 7 , wherein the operating selectively closing the second and the fourth current control sub-circuits such that at least one of an amplitude and a width of the biphasic pulse is different for at least two of the multiple pairs of electrodes.

9. The method of claim 7 , wherein the selectively coupling comprises switching between the multiple pairs of electrodes at a predetermined switching period, and wherein the biphasic pulse for each of the multiple pairs of electrodes is generated at a time corresponding to an integer multiple of predetermined switching period.

10. The method of claim 9 , wherein the predetermined switching period comprises a product of the total number of the multiple electrode pairs and the maximum biphasic stimulation pulse.

Assignees

• Univ Vanderbilt

Inventors

• Goldfarb Michael
• Ha Kevin
• Truex Don

Classifications

• A61N1/025 Primary

  Digital circuitry features of electrotherapy devices, e.g. memory, clocks, processors · CPC title

• A61N1/32

  alternating or intermittent currents {(applying electric fields by inductive or capacitive coupling A61N1/40; microwave apparatus A61N5/02)} · CPC title

• A61N1/36003

  of motor muscles, e.g. for walking assistance · CPC title

• A61N1/36125 Primary

  Details of circuitry or electric components · CPC title